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DTSTART;TZID=America/Los_Angeles:20210408T110000
DTEND;TZID=America/Los_Angeles:20210408T120000
DTSTAMP:20260420T115309
CREATED:20210402T171834Z
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UID:10000225-1617879600-1617883200@brain.uci.edu
SUMMARY:Development and Cell Biology Spring Seminar Series with Dr. Javier Apfeld
DESCRIPTION:C. elegans Processes Sensory Information to Choose Between Freeloading and Self-defense Strategies \nJoin the UCI Department of Developmental and Cell Biology in a virtual seminar with Dr. Javier Apfield\, Assistant Professor of the College of Science of Northeastern University. \nAbstract:\nHydrogen peroxide is the preeminent chemical weapon that organisms use for combat. Individual cells rely on conserved defenses to prevent and repair peroxide-induced damage\, but whether similar defenses might be coordinated across cells in animals remains poorly understood. In this seminar\, I will discuss our recent findings showing that in the nematode Caenorhabditis elegans a neuronal circuit processes information perceived by two sensory neurons to control the induction of hydrogen-peroxide defenses in target tissues. We found that catalases produced by Escherichia coli\, the nematode’s food source\, can deplete hydrogen peroxide from the local environment and thereby protect the nematodes. In the presence of E. coli\, the nematode’s neurons signal via TGFβ-insulin/IGF1 relay to target tissues that they need not induce catalases and other hydrogen-peroxide defenses. This adaptive strategy is the first example of a multicellular organism modulating its defenses when it expects to freeload from the protection provided by molecularly orthologous defenses from another species. \n  \nPlease join via Zoom: https://uci.zoom.us/j/91254995926?pwd=N3hnanM2a1AwMUlDOUxpSkxTeTRtQT09 \nMeeting ID: 912 5499 5926 \nPasscode: 634218 \n 
URL:https://brain.uci.edu/event/development-and-cell-biology-spring-seminar-series-with-dr-javier-apfeld/
LOCATION:Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Students, Faculty, Staff Only
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210408T130000
DTEND;TZID=America/Los_Angeles:20210408T140000
DTSTAMP:20260420T115309
CREATED:20210406T233951Z
LAST-MODIFIED:20210406T233951Z
UID:10000226-1617886800-1617890400@brain.uci.edu
SUMMARY:Elizabeth Head\, MA\, PhD
DESCRIPTION:Alzheimer Disease in Down Syndrome: Cerebrovascular and Neuroinflammation Contributions \nPlease join the UCI Department of Microbiology and Molecular Genetics in a virtual seminar with Dr. Elizabeth Head\, from the UCI School of Medicine. \n  \nFree to attend. Registration required.\nClick here for more information. 
URL:https://brain.uci.edu/event/elizabeth-head-ma-phd/
LOCATION:Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Students, Faculty, Staff Only
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210415T110000
DTEND;TZID=America/Los_Angeles:20210415T120000
DTSTAMP:20260420T115309
CREATED:20210311T200144Z
LAST-MODIFIED:20210311T200144Z
UID:10000219-1618484400-1618488000@brain.uci.edu
SUMMARY:ICAN Seminar -Dr. Arif Hamid
DESCRIPTION:Dopamine waves as a mechanism for spatiotemporal credit assignment. \nJoin the UC Irvine Center for Addiction Neuroscience in a virtual ICAN Seminar featuring Arif Hamid\, PhD\, from Brown University. \nAbstract\nSignificant evidence supports the view that dopamine shapes reward-learning by encoding prediction errors. However\, it is unknown whether dopamine decision-signals are tailored to the functional specialization of target regions. In this talk\, I will report on a novel set of wave-like spatiotemporal activation patterns in dopamine axons (and release) across the dorsal striatum that switch between different activational motifs. At reward delivery\, waves are altered by task demands\, propagating from dorsomedial to dorsolateral striatum during instrumental contingencies\, and in the opponent direction when rewards are independent of animal behavior. I will demonstrate that our results are consistent with a computational architecture in which striatal dopamine signals are sculpted by inference about agency\, and provide evidence for a spatiotemporally “vectorized” role of dopamine in credit assignment directed toward specialized “expert” striatal subregions.
URL:https://brain.uci.edu/event/ican-seminar-dr-arif-hamid/
LOCATION:Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Students, Faculty, Staff Only
ATTACH;FMTTYPE=:
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210420T110000
DTEND;TZID=America/Los_Angeles:20210420T120000
DTSTAMP:20260420T115309
CREATED:20210408T230342Z
LAST-MODIFIED:20210408T230342Z
UID:10000229-1618916400-1618920000@brain.uci.edu
SUMMARY:CNCM Seminar with Orkide Koyuncu\, PhD
DESCRIPTION:Alpha-Herpesvirus Neuroinvasion: Deciphering the Long Path Toward Latency \nPlease join the UCI Center for Neural Circuit Mapping in a virtual seminar with Dr. Orkide Koyuncu\, Assistant Professor in the Department of Microbiology and Molecular Genetics of the UCI School of Medicine. \nFree to attend. Registration required.  \nFor more information\, please visit:  www.cncm.som.uci.edu/seminars
URL:https://brain.uci.edu/event/cncm-seminar-with-orkide-koyuncu-phd/
LOCATION:Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Students, Faculty, Staff Only
ATTACH;FMTTYPE=:
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210420T160000
DTEND;TZID=America/Los_Angeles:20210420T170000
DTSTAMP:20260420T115309
CREATED:20200731T220115Z
LAST-MODIFIED:20200731T220115Z
UID:10000160-1618934400-1618938000@brain.uci.edu
SUMMARY:Steven Petrou\, Ph.D.
DESCRIPTION:Dr. Steven Petrou\, professor and director of the Florey Institute of Neuroscience and Mental Health\, is one of the speakers in the 2020/21 EpiCenter Seminar Series. \nDr. Petrou is a leader in the field of ion channel neuropathies\, with a particular focus on rare epileptic encephalopathies. These are a range of genetic epilepsies affecting infants and young children with devasting impacts for them and their families.
URL:https://brain.uci.edu/event/steven-petrou-ph-d/
LOCATION:Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students, Faculty, Staff Only
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210427T110000
DTEND;TZID=America/Los_Angeles:20210427T120000
DTSTAMP:20260420T115309
CREATED:20201023T163621Z
LAST-MODIFIED:20201023T163621Z
UID:10000191-1619521200-1619524800@brain.uci.edu
SUMMARY:CNLM Virtual Colloquium  with Corey Harwell\, Ph.D.
DESCRIPTION:Development and diversity of neural cell types in the septum \nThe CNLM will be hosting Dr. Corey Harwell\, from the Department of Neurobiology of Harvard Medical School\, in a virtual colloquium where he will present his latest research. \nAbstract: The septum is ventral forebrain structure responsible for the regulation of emotional states including anxiety\, fear and depression. The septum contains an extremely diverse array of short- and long-range projecting GABAergic neurons distributed across its two histological subdivisions\, the medial and lateral septal nuclei. Both of these regions are heavily interconnected with other brain areas. It is currently unclear how septal neuronal diversity and circuit wiring are specified during development. Using molecular genetics and single-cell/nuclei RNA-seq we have begun to unravel the developmental logic for producing diverse neural cell types in the septum. Our future work is focused on understanding the specific contribution of developmentally specified neural cell types to the regulation of internal states carried out by the septum. 
URL:https://brain.uci.edu/event/cnlm-virtual-colloquium-with-corey-harwell-ph-d/
LOCATION:Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=:
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210427T120000
DTEND;TZID=America/Los_Angeles:20210427T130000
DTSTAMP:20260420T115309
CREATED:20210419T214722Z
LAST-MODIFIED:20210419T214722Z
UID:10000235-1619524800-1619528400@brain.uci.edu
SUMMARY:Conte Center Seminar Series with Catherine J. Peña\, PhD
DESCRIPTION:Transcriptomic and epigenomic consequences of early life stress \nThe Conte Center @ UCI will be hosting Catherine J. Peña\, PhD\, Assistant Professor\, from Princeton Neuroscience Institute. \nTo attend\, please visit: https://zoom.us/j/95134666233?pwd=QitYQnZXVXVJY09WZlhzdzJBSGU3QT09
URL:https://brain.uci.edu/event/conte-center-seminar-series-with-catherine-j-pena-phd/
LOCATION:Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Students, Faculty, Staff Only
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