BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Brain - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Brain X-ORIGINAL-URL:https://brain.uci.edu X-WR-CALDESC:Events for Brain REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/Los_Angeles BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20210314T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20211107T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20220313T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20221106T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20230312T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20231105T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20240310T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20241103T090000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220505T090000 DTEND;TZID=America/Los_Angeles:20220506T150000 DTSTAMP:20260421T192340 CREATED:20210824T213007Z LAST-MODIFIED:20220314T172921Z UID:10000262-1651741200-1651849200@brain.uci.edu SUMMARY:2022 CNLM Spring Conference DESCRIPTION:Since 1982\, the CNLM has hosted an annual scientific conference in the spring to discuss recent advances in the field and launch new collaborations and synergies. The conferences include several themed symposia\, short presentations by trainees\, panel discussions\, and keynote lectures. It is a crucial scientific development opportunity for students and postdocs as well as a faculty. Attendance is by invitation only (except for the triennial international conference – see 2018 below)\, and the program is developed by a committee of CNLM faculty fellows\, including external fellows. The conferences are highly renowned for their intellectual atmosphere\, use of the 50/50 discussion rule\, and the special edited volumes that result from them. Typical attendance at the annual conference is between 100-120 attendees. Attendance at the 2018 meeting exceeded 1\,000 scientists.  \nTo learn more about past conferences\, visit: https://cnlm.uci.edu/scientific-activities/spring-meeting/ URL:https://brain.uci.edu/event/2022-cnlm-spring-conference/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/SpringConferenceGraphics_FinalRevised-01.png ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220525T150000 DTEND;TZID=America/Los_Angeles:20220525T170000 DTSTAMP:20260421T192340 CREATED:20220207T185913Z LAST-MODIFIED:20220216T000055Z UID:10000296-1653490800-1653498000@brain.uci.edu SUMMARY:2022 CNLM Awards Ceremony DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for the 2021 CNLM Awards Ceremony The CNLM offers awards to exceptional postdoctoral researchers\, graduate trainees\, undergraduates students\, and faculty.  Awardees will be presented with a plaque and $1\,000 stipend and will be invited to present their work in brief Elevator Pitch format to the UCI academic community and the public at our annual CNLM Awards Ceremony. \n  \nApplications for the 2021 CNLM Awards are due in February. Stay tuned! \nFor more information\, please visit: https://cnlm.uci.edu/awards/ \n  URL:https://brain.uci.edu/event/2022-cnlm-awards-ceremony/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:All,Community,Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/cnlm-awards-slide-2022-01.png ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220607T110000 DTEND;TZID=America/Los_Angeles:20220607T120000 DTSTAMP:20260421T192340 CREATED:20220517T152320Z LAST-MODIFIED:20220517T152320Z UID:10000324-1654599600-1654603200@brain.uci.edu SUMMARY:James L. McGaugh Distinguished Lecture: Kay Tye\, PhD DESCRIPTION:Neural Representations of Social Homeostasis \nJoin the UCI Department of Neurobiology and Behavior for a virtual seminar featuring\, Dr. Kay Tye of the Salk Institute. \nAbstract: \nHow does our brain rapidly determine if something is good or bad? How do we know our place within a social group? How do we know how to behave appropriately in dynamic environments with ever-changing conditions?\nThe Tye Lab is interested in understanding how neural circuits important for driving positive and negative motivational valence (seeking pleasure or avoiding punishment) are anatomically\, genetically and functionally arranged.  We study the neural mechanisms that underlie a wide range of behaviors ranging from learned to innate\, including social\, feeding\, reward-seeking and anxiety-related behaviors. We have also become interested in “social homeostasis” — how our brains establish a preferred set-point for social contact\, and how this maintains stability within a social group.  How are these circuits interconnected with one another\, and how are competing mechanisms orchestrated on a neural population level? We employ optogenetic\, electrophysiological\, electrochemical\, pharmacological and imaging approaches to probe these circuits during behavior. URL:https://brain.uci.edu/event/james-l-mcgaugh-distinguished-lecture-kay-tye-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-2.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220609T160000 DTEND;TZID=America/Los_Angeles:20220609T180000 DTSTAMP:20260421T192340 CREATED:20220524T152420Z LAST-MODIFIED:20220524T153522Z UID:10000326-1654790400-1654797600@brain.uci.edu SUMMARY:Society of Behavioral Medicine Information Event: Margaret Schneider\, PhD DESCRIPTION:An introduction to the Society of Behavioral Medicine: Professional development & networking opportunities for students & early-career scientists \nThe Society of Behavioral Medicine has the resources and tools you need to advance your career. SBM offers networking\, mentoring\, continuing education\, webinars\, presentation opportunities\, publication opportunities\, a Student Special Interest Group\, and much more. Join us for an information session organized by SBM leadership at UC Irvine featuring Dr. Margaret Schneider\, President of the Society of Behavioral Medicine. Come to learn and network with SBM members and fellow UCI scientists from all career stages. URL:https://brain.uci.edu/event/society-of-behavioral-medicine-information-event-margaret-schneider-phd/ LOCATION:Thorp Conference Center\, Gross Hall\, 4th Floor\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-5.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220614T120000 DTEND;TZID=America/Los_Angeles:20220614T130000 DTSTAMP:20260421T192340 CREATED:20220602T201944Z LAST-MODIFIED:20220602T201944Z UID:10000331-1655208000-1655211600@brain.uci.edu SUMMARY:Albert La Spada\, PhD DESCRIPTION:Deconstructing Neurodegenerative Proteinopathies: From Pathology of Neuron Demise to Therapeutic Interventon \nJoin the Department of Neurobiology and Behavior in a hybrid seminar featuring Dr. Albert La Spada. \n \nAbstract:Both rare inherited neurodegenerative disorders and common sporadic neurodegenerative diseases are caused by misfolded proteins that accumulate in neurons and glia of affected patients.  The CAG – polyglutamine (PolyQ) repeat diseases are one category of inherited neurodegenerative disorders that are caused by the expansion of a CAG triplet repeat\, resulting in a protein with an abnormally extended polyglutamine (polyQ) tract.  The repeat expansions in these diseases occur in the coding region\, and lead to the production of aggregate-prone proteins.  Of the nine CAG-PolyQ diseases\, I have been studying the disease pathogenesis of three such disorders: X-linked spinal & bulbar muscular atrophy (SBMA/Kennedy’s disease)\, Huntington’s disease\, and spinocerebellar ataxia type 7.  To determine the cellular and molecular basis of these diseases\, I have relied upon mouse models and human stem cell models\, and through these efforts\, I have uncovered a central role for transcription dysregulation\, altered proteostasis\, and bioenergetic abnormalities in the pathogenesis of these disorders.  Unbiased transcriptome analysis and directed studies of cell-type contribution have yielded crucial insights into the nature of these diseases\, and have revealed targets and pathways likely amenable to therapeutic manipulation. \nHybrid Event\nThe seminar will be live-streamed via zoom and in person.\nPlease RSVP to let us know how you will attend and receive zoom link. \nIn-Person Meeting: Interdisciplinary Science and Engineering Building (ISEB) auditorium URL:https://brain.uci.edu/event/albert-la-spada-phd/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/06/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220909T080000 DTEND;TZID=America/Los_Angeles:20220909T153000 DTSTAMP:20260421T192340 CREATED:20220829T183218Z LAST-MODIFIED:20220829T184251Z UID:10000335-1662710400-1662737400@brain.uci.edu SUMMARY:33rd Annual Southern California Alzheimer’s Disease Research Conference DESCRIPTION:Dementia across the lifespan…\nJoin UCI MIND\, Alzheimer’s Orange County\, and Alzheimer’s Association for the 33rd Annual Southern California Alzheimer’s Disease Research Conference. This hybrid conference will cover a wide range of topics across the lifespan\, such as Down syndrome\, frontotemporal dementia\, early-onset Alzheimer’s\, the oldest-old\, and even more.To view the agenda\, see our exhibitors\, read about our esteemed speakers\, and more\, visit conference.mind.uci.edu. \nThis is a hybrid event\, taking place in person at the Irvine Marriott Hotel and virtually via Zoom.  \n  \n  URL:https://brain.uci.edu/event/33rd-annual-southern-california-alzheimers-disease-research-conference/ LOCATION:Irvine Marriott Hotel\, 18000 Von Karman Ave\, Irvine\, CA\, 92612 CATEGORIES:All,Community,Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/2022-Alzheimers-Conference.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220913T160000 DTEND;TZID=America/Los_Angeles:20220913T170000 DTSTAMP:20260421T192340 CREATED:20220829T181639Z LAST-MODIFIED:20220829T181834Z UID:10000334-1663084800-1663088400@brain.uci.edu SUMMARY:Susan B. Perlman\, PhD DESCRIPTION:Neuroscientific Evaluation of Risk in Early Childhood Psychopathology: Integrating Proximal and Distal Factors. \n\n\n\nJoin the Conte Center at UCI for a seminar featuring Dr. Susan B. Perlman\, Associate Professor of Psychiatry at the Washington University of St. Louis. \nTo learn more\, please visit: https://contecenter.uci.edu/seminar-series/ URL:https://brain.uci.edu/event/susan-b-perlman-phd/ LOCATION:Virtual/Hybrid Event (In person at Gross Hall 4th Floor Conference Room)\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/image-1-e1661797027822.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220920T100000 DTEND;TZID=America/Los_Angeles:20220920T110000 DTSTAMP:20260421T192340 CREATED:20220829T180611Z LAST-MODIFIED:20220829T180611Z UID:10000333-1663668000-1663671600@brain.uci.edu SUMMARY:Li Zhang\, Ph.D DESCRIPTION:CNCM Seminar  \nJoin the UCI Center for Neural Circuit Mapping in a seminar featuring Dr. Li Zhang\, Professor of Physiology & Neuroscience and Director of the Center for Neural Circuits and Sensory Processing Disorders of the Keck School of Medicine of USC. URL:https://brain.uci.edu/event/li-zhang-ph-d/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220920T100000 DTEND;TZID=America/Los_Angeles:20220920T110000 DTSTAMP:20260421T192340 CREATED:20220829T183851Z LAST-MODIFIED:20220829T184131Z UID:10000336-1663668000-1663671600@brain.uci.edu SUMMARY:Maurizio Taglialatela\, MD\, PhD DESCRIPTION:EpiCenter Seminar Series  \nJoin the UCI Epilepsy Research Center featuring Maurizio Taglialatela\, MD\, PhD\, Professor of Pharmacology\, University of Naples Federico II\, in a virtual seminar. URL:https://brain.uci.edu/event/maurizio-taglialatela-md-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/Maurizio-Taglialatela.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220928T100000 DTEND;TZID=America/Los_Angeles:20220928T110000 DTSTAMP:20260421T192340 CREATED:20220913T183033Z LAST-MODIFIED:20220913T183033Z UID:10000338-1664359200-1664362800@brain.uci.edu SUMMARY:CNCM Seminar: Peyman Golshani\, MD\, PhD DESCRIPTION:New open-source tools for imaging neuronal activity in freely behaving animals \nJoin the UCI Center for Neural Circuit Mapping in a hybrid conference featuring Dr. Peyman Golshani\, Professor of Neurology at the David Geffen School of Medicine\, UCLA. \nAbstract: \nDr. Golshani obtained his MD/PhD from UC Irvine and UC Davis where he trained under the mentorship of Dr. Edward G. Jones on the development of corticothalamic synapse. He then completed his Neurology residency at UCLA and obtained postdoctoral training with Dr. Felix Schweizer and Dr. Guoping Fan where he studied the role of DNA methylation in development of cortical circuits. He then became faculty and in collaboration with Dr. Portera-Cailliau and Dr. Stelios Smirnakis studied the developmental desynchronization of internally generated activity in the cerebral cortex. His independent laboratory now investigates how cortical microcircuits in the awake behaving animal encode sensory input and how disorders such as autism and developmental epilepsies disrupt functional cortical connectivity. \nHybrid Seminar \nIn-Person: Interdisciplinary Science & Engineering Building ISEB 2020 \nVirtual: via Zoom URL:https://brain.uci.edu/event/cncm-seminar-peyman-golshani-md-phd/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/Peyman-Golshani-400x400-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221004T100000 DTEND;TZID=America/Los_Angeles:20221004T110000 DTSTAMP:20260421T192340 CREATED:20220929T153733Z LAST-MODIFIED:20220929T154020Z UID:10000350-1664877600-1664881200@brain.uci.edu SUMMARY:Rongxin Fang\, PhD DESCRIPTION:Analysis of Cortical Evolution with Specially Resolved Transcriptome Imaging \nJoin the UCI Center for Neural Circuit Mapping in a virtual seminar featuring Dr. Rongxin Fang. Dr. Fang is currently a Howard Hughes Medical Institute fellow of the Dameon Runyon Cancer Research Foundation at Harvard University. He received his Ph.D in Bioinformatics at the University of California\, San Diego. URL:https://brain.uci.edu/event/rongxin-fang-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-5.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221004T110000 DTEND;TZID=America/Los_Angeles:20221004T120000 DTSTAMP:20260421T192340 CREATED:20220913T175619Z LAST-MODIFIED:20220913T175640Z UID:10000337-1664881200-1664884800@brain.uci.edu SUMMARY:Neurobiology and Behavior Seminar with Dr. Alan Urban DESCRIPTION:How can functional ultrasound imaging (fUSI) impact your research\, and what’s next? \nJoin the UCI Department of Neurobiology and Behavior in a hybrid seminar featuring Dr. Alan Urban\, Assistant Professor of the Department of Neurosciences of KU Leuven Research. \nAbstract: \nFunctional ultrasound imaging (fUSI) is based on Doppler ultrasound to track changes in cerebral blood volume as an indirect readout of evoked neuronal activity. It is similar to fMRI but with better spatiotemporal resolution and fewer technical constraints. Indeed\, fUSI can be performed in head-fixed or freely behaving rodents and allows volumetric images of the entire mouse brain. Proof of concept studies has been conducted in many species\, including primates and humans. fUSI has reached maturity\, and open access hardware and software solutions developed at NERF contribute to a faster and broader adoption by the neuroscience community. This seminar aims to introduce the physical basis of fUSI and present state-of-the-art in the field while providing detailed examples of the most impactful fUSI research. I will also discuss the latest capabilities of fUSI and suggest routes for improving the fUSI technology in the next few years. \nHybrid Event\nThe seminar will be live-streamed via zoom and in person.\nPlease RSVP to let us know how you will attend and receive zoom link. \nIn-Person Meeting: Dale Melbourne Herklotz Conference Room\, the Center for the Neurobiology of Learning and Memory 300 Qureshey Research Lab URL:https://brain.uci.edu/event/neurobiology-and-behavior-seminar-with-dr-alan-urban/ LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/Alan-Urban.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221007T100000 DTEND;TZID=America/Los_Angeles:20221007T110000 DTSTAMP:20260421T192340 CREATED:20220929T160851Z LAST-MODIFIED:20220929T161201Z UID:10000353-1665136800-1665140400@brain.uci.edu SUMMARY:Serena M. Dudek\, PhD DESCRIPTION:Join the Department of Anatomy and Neurobiology in a virtual seminar featuring Dr. Serena M. Dudek \, Deputy Chief and Neurobiology Laboratory and Principal Investigator of the National Institute of Environmental Health Sciences. URL:https://brain.uci.edu/event/serena-m-dudek-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-8-e1664467912680.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221007T120000 DTEND;TZID=America/Los_Angeles:20221007T130000 DTSTAMP:20260421T192340 CREATED:20221004T205910Z LAST-MODIFIED:20221004T210115Z UID:10000355-1665144000-1665147600@brain.uci.edu SUMMARY:BME Seminar Series: How does neuronal activity protect the cortex from stroke? DESCRIPTION:Abstract: Stroke is the fifth leading cause for death in the U.S. and No. 1 cause for long term disability. Traditionally\, stroke has been studied in animal models using cellular and molecular techniques\, but little attention has been paid to neuronal activity. In this talk\, I will describe surprising findings in a rat model of ischemic stroke relating sensory stimulation-evoked neuronal activity and stroke. Depending on delivery timing\, sensory stimulation-evoked neuronal activity can protect the cortex from impending damage or exacerbate the damage. I will further elucidate the neuronal and vascular mechanisms underlying the protection and exacerbation processes and describe our accumulating evidence that neuronal activity and cortical structure-function relationship are pivotal players in understanding ischemic stroke outcome. \nBiography: Ron D. Frostig is a professor of neurobiology and behavior and biomedical engineering at UCI. He received his bachelor’s degree in biology and his master’s degree in neurobiology from the Hebrew University\, Israel. He received his doctorate in neuroscience at UCLA\, and was a postdoctoral research scholar in neurobiology at the Rockefeller University. His lab’s major research interests include basic and pre-clinical studies of neocortical structure and function with an emphasis on plasticity. URL:https://brain.uci.edu/event/bme-seminar-series-how-does-neuronal-activity-protect-the-cortex-from-stroke/ LOCATION:McDonnell Douglas Engineering Auditorium\, 314 Los Trancos Drive\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/FrostigLab-Logo-v7.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221011T100000 DTEND;TZID=America/Los_Angeles:20221011T110000 DTSTAMP:20260421T192340 CREATED:20220929T154800Z LAST-MODIFIED:20220929T154800Z UID:10000351-1665482400-1665486000@brain.uci.edu SUMMARY:Sean Foxley\, PhD DESCRIPTION:Join the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Sean Foxley of the University of Chicago. URL:https://brain.uci.edu/event/sean-foxley-phd/ LOCATION:CA CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-6.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221019T120000 DTEND;TZID=America/Los_Angeles:20221019T160000 DTSTAMP:20260421T192340 CREATED:20221005T155834Z LAST-MODIFIED:20221005T155935Z UID:10000356-1666180800-1666195200@brain.uci.edu SUMMARY:UC Irvine Neuropolitics Symposium DESCRIPTION:Cognitive Decline and Political Leadership \nJoin the UCI Center for Neuropolitics in a virtual symposium to discuss cognitive decline among politicians. \nCognitive deterioration of politicians (including diminished memory\, impaired decision-\nmaking\, mood alterations\, and dementia) is a critical emerging issue. This Symposium\nwill address the current state and future directions of assessment of cognitive function\nand decline among politicians. As professions such as law and medicine are addressing\ncognitive effects of age\, their insights may inform development of the proper strategy\nwithin politics. \n  \nClick here to view the symposium agenda URL:https://brain.uci.edu/event/uc-irvine-neuropolitics-symposium/ LOCATION:Virtual Event CATEGORIES:Community,Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221025T100000 DTEND;TZID=America/Los_Angeles:20221025T110000 DTSTAMP:20260421T192340 CREATED:20220929T155114Z LAST-MODIFIED:20221018T171916Z UID:10000352-1666692000-1666695600@brain.uci.edu SUMMARY:Li Zhang\, Ph.D. DESCRIPTION:“Neural circuits for valence coding\, emotional states\, and motivated behaviors” \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Li Zhang of USC Medical School. \nAbstract: \nThe topic is about our recent studies on neural circuits in the medial preoptic area (MPOA) of the hypothalamus. MPOA plays a critical role in parental and prosocial behaviors via subpopulations of its GABAergic neurons. We now show that MPOA can be more generally viewed to serve as a critical hub to mediate both negative and positive emotional states and related behaviors through its glutamatergic and GABAergic neurons\, respectively\, with the former encoding extremely negative valence and mediating anxiety-like behaviors\, and the latter\, oppositely\, encoding positive valence and producing rewarding effects.  I will discuss the circuitry underlying how MPOA coordinately and antagonistically mediates behaviors related to different emotional states. URL:https://brain.uci.edu/event/li-zhang-ph-d-2/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-7.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221025T120000 DTEND;TZID=America/Los_Angeles:20221025T130000 DTSTAMP:20260421T192340 CREATED:20220929T163455Z LAST-MODIFIED:20221014T155243Z UID:10000354-1666699200-1666702800@brain.uci.edu SUMMARY:NextGen Epilepsy Seminar: Jessie Buth and Christos Lisgaras DESCRIPTION:Join the UCI Epilepsy Research Center in a virtual seminar of their NextGen Epilepsy Seminar Series featuring Jessie Buth\, PhD Student of the Novitch Lab at UCLA and Christos Lisgaras\, PhD\, Postdoctoral Fellow of the Scharfman Lab at the Nathan S. Kline Institute for Psychiatric Research. \nThe seminar will be hosted by Robert Hunt\, PhD and will feature Jessie Buth presenting Investigating the Role of KDM6B in Human Brain Development and Autism Spectrum Disorder Using Stem Cell Models and Christos Lisgaras presenting Deciphering the Role of Hippocampal Area CA2 in Temporal Lobe Epilepsy Using Closed-Loop Optogenetics.  URL:https://brain.uci.edu/event/nextgen-epilepsy-seminar-jessie-buth-and-christos-lisgaras/ LOCATION:CA CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/jessieButh-Christos-Lisgaras-01.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221025T130000 DTEND;TZID=America/Los_Angeles:20221025T140000 DTSTAMP:20260421T192340 CREATED:20220929T151034Z LAST-MODIFIED:20220929T151034Z UID:10000349-1666702800-1666706400@brain.uci.edu SUMMARY:Rajendra Morey\, MD\, MS DESCRIPTION:Leveraging Team Science at a Global Scale to Investigate the Neurobiology of PTSD \nJoin the Conte Center @ UCI for a virtual seminar featuring Dr. Rajendra Morey\, Professor of Psychiatry and Behavioral Sciences at Duke University. URL:https://brain.uci.edu/event/rajendra-morey-md-ms/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/Rajendra-Morey-Headshot.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221028T110000 DTEND;TZID=America/Los_Angeles:20221028T120000 DTSTAMP:20260421T192340 CREATED:20221027T192301Z LAST-MODIFIED:20221027T192301Z UID:10000368-1666954800-1666958400@brain.uci.edu SUMMARY:Patrick J. Lao\, PhD DESCRIPTION:Please join the UCI Center for Aging Research in Down Syndrome (CFAR-DS) Oct. 28 at 11 am PT  for their Seminar Series presentationtitled Alzheimer’s disease and vascular neuroimaging in adults with Down syndrome\, presented by Patrick J. Lao\, PhD. \nPatrick J. Lao\, PhD is an Assistant Professor of Neurology Sciences at the Taub Institute\, Sergeivsky Center\, and Department of Neurology at Columbia University. He earned his Ph.D. at the University of Wisconsin-Madison in Medical Physics and completed his postdoctoral training at Columbia University in vascular MRI and applied cross-cultural neuropsychology. His research uses multimodal neuroimaging and plasma-based biomarkers to study Alzheimer’s disease. Areas of interest include applying these methods to adults with Down syndrome and in community-based settings. \nThis event will take place via Zoom: \n\n\n\n\n\n\n\n\n\n\nhttps://ucihealth.zoom.us/j/92151970794?pwd=NkMxbWh2aklXWFU4K1hsRUZqOEpKZz09 \nMeeting ID: 921 5197 0794\nPasscode: 954508 URL:https://brain.uci.edu/event/patrick-j-lao-phd/ LOCATION:Virtual Event CATEGORIES:Community,Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/Patrick-Lau-Headshot.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221104T140000 DTEND;TZID=America/Los_Angeles:20221104T150000 DTSTAMP:20260421T192340 CREATED:20221027T154020Z LAST-MODIFIED:20221027T154020Z UID:10000361-1667570400-1667574000@brain.uci.edu SUMMARY:Takaki Komiyama\, PhD DESCRIPTION:Motor cortex circuits for learned movements \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Takaki Komiyama\, Professor and Vice Chair of the Department of Neurobiology at UC San Diego. \nThis hybrid seminar will be taking place in the Interdisciplinary Science and Engineering Building (ISEB)2020 & Telecast via Zoom. \n \nAbstract: \nMotor cortex circuits are highly plastic\, enabling adaptive control and learning of body movements. I will discuss two projects. In the first project\, we studied the spatial and functional specificity of synaptogenesis that occurs during motor learning. This was done by longitudinal functional imaging of dendritic spines followed by correlated electron microscopy. In the second project\, we are investigating the roles of motor cortex ensemble activity in the control of learned movements. This is done by population calcium imaging combined with holographic two-photon optogenetic stimulation of neural ensembles. URL:https://brain.uci.edu/event/takaki-komiyama-phd/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-1.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221108T100000 DTEND;TZID=America/Los_Angeles:20221108T110000 DTSTAMP:20260421T192340 CREATED:20221027T162454Z LAST-MODIFIED:20221027T162454Z UID:10000362-1667901600-1667905200@brain.uci.edu SUMMARY:Trygve Bakken\, Ph.D. DESCRIPTION:Cellular diversity and evolutionary specializations in human neocortex \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Trygve Bakken\, Assistant Investigator at the Allen Institute for Brain Science in a hybrid seminar. URL:https://brain.uci.edu/event/trygve-bakken-ph-d/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-3.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221108T110000 DTEND;TZID=America/Los_Angeles:20221108T120000 DTSTAMP:20260421T192340 CREATED:20220922T151235Z LAST-MODIFIED:20221005T181006Z UID:10000340-1667905200-1667908800@brain.uci.edu SUMMARY:Alyson Zalta\, Ph.D DESCRIPTION:Exploring morning light therapy as a novel treatment for traumatic stress \nCNLM Colloquium UCI Spotlight Series \nJoin the CNLM in a hybrid colloquium featuring Dr. Alyson Zalta\, Associate Professor of Psychological Science at UC Irvine. \nDescription: \nTrauma contributes to a wide variety of mental health problems including posttraumatic stress disorder (PTSD)\, depression\, anxiety\, substance use\, and suicidality. Although front-line psychotherapies and pharmacotherapies exist for traumatic stress\, evidence suggests that many individuals fail to receive treatment\, remain symptomatic despite treatment\, or drop out of treatment before its conclusion. Uptake of these treatments is poor for several reasons including stigma\, avoidance\, unpleasant side effects\, and poor accessibility. New treatments are needed for traumatic stress that can overcome these critical barriers to care while targeting the underlying biological mechanisms of the pathology. Morning light treatment has good potential as a novel non-invasive\, low risk\, scalable treatment for traumatic stress. Evidence suggests that morning light may improve traumatic stress by reducing reactivity in the amygdala\, a brain region implicated in the pathophysiology of PTSD and anatomically linked to circadian photoreceptors in the eye. This seminar will describe the results of a randomized pilot trial that provides initial proof-of-concept that light treatment can improve traumatic stress and preliminary results from an ongoing randomized clinical trial aimed at evaluating the brain mechanisms underlying morning light therapy for traumatic stress. \n  \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. URL:https://brain.uci.edu/event/alyson-zalta-ph-d/ LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image.jpeg ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221109T160000 DTEND;TZID=America/Los_Angeles:20221109T170000 DTSTAMP:20260421T192340 CREATED:20221027T165046Z LAST-MODIFIED:20221027T165046Z UID:10000365-1668009600-1668013200@brain.uci.edu SUMMARY:Jennifer Gelinas\, MD\, PhD DESCRIPTION:EpiCenter Seminar Series\nJoin the UCI Epilepsy Research Center for a hybrid seminar featuring Dr. Jennifer Gelinas\, Assistant Professor of Neurology from Columbia University. URL:https://brain.uci.edu/event/jennifer-gelinas-md-phd/ LOCATION:CA CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-5.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221117T100000 DTEND;TZID=America/Los_Angeles:20221117T110000 DTSTAMP:20260421T192340 CREATED:20221027T164057Z LAST-MODIFIED:20221027T164113Z UID:10000364-1668679200-1668682800@brain.uci.edu SUMMARY:Yongsoo Kim\, PhD DESCRIPTION:Neuronal and non-neuronal cell type mapping in the mouse brain \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Yongsoo Kim\, Associate Professor from the Department of Neural and Behavioral Sciences\, College of Medicine from Penn State. URL:https://brain.uci.edu/event/dr-yongsoo-kim/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-2.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221117T160000 DTEND;TZID=America/Los_Angeles:20221117T170000 DTSTAMP:20260421T192340 CREATED:20221027T165601Z LAST-MODIFIED:20221027T165601Z UID:10000366-1668700800-1668704400@brain.uci.edu SUMMARY:Daniel Vogt\, PhD DESCRIPTION:Join the UCI Epilepsy Research Center in a hybrid seminar featuring Dr. Daniel Vogt\, Assistant Professor of Pediatrics and Human Development at Michigan State University. URL:https://brain.uci.edu/event/daniel-vogt-phd/ LOCATION:CA CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-6.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221205T100000 DTEND;TZID=America/Los_Angeles:20221205T110000 DTSTAMP:20260421T192340 CREATED:20221128T232720Z LAST-MODIFIED:20221201T175724Z UID:10000375-1670234400-1670238000@brain.uci.edu SUMMARY:Georg F. Striedter\, Ph.D. DESCRIPTION:Evolutionary Conservation versus Change in Brains and Other Biological Systems \n\n\n\nComparative neuroanatomists in recent years have made great progress in delineating the conserved “Bauplan” of vertebrate brains. However\, brains also evolved some major “new” brain regions that do not fit neatly into the conserved Bauplan view. In particular\, it appears that ray-finned fishes and amniotes have independently evolved a dorsal pallium\, which comprises the neocortex in mammals. Even for homologous brain areas\, changes in connectivity have been common – and often convergent between distantly related species\, such as primates and birds. To expand our understanding of brain evolution\, consider an analogy to evolving molecular systems. In this analogy\, highly conserved genes (including “human disease genes”) correspond to conserved brain regions\, whereas genetic losses and gains correspond to the loss and gain of major brain regions. Moreover\, molecular pathways and interactomes are analogous to neuroanatomical circuits; they\, too\, exhibit significant variation\, nicely captured by the phrase “genetic rewiring.” Because of this molecular variation\, the systems-level function(s) of individual genes and proteins can vary significantly over evolutionary time. This “causal drift” makes it difficult to extrapolate from “simple systems” to more complex networks\, and from model species to humans. Analogs of causal drift in molecular networks have been suggested also for neuronal networks (e.g. neocorticalization)\, but they have not been studied thoroughly. Filling that knowledge gap would be worthwhile. URL:https://brain.uci.edu/event/evolutionary-conservation-versus-change-in-brains-and-other-biological-systems-featuring-georg-f-striedter-ph-d/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB)\, 4020 (Telecast via Zoom)\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/11/Georg-F.-Striedter-PhD-Headshot.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221207T153000 DTEND;TZID=America/Los_Angeles:20221207T193000 DTSTAMP:20260421T192340 CREATED:20221201T212943Z LAST-MODIFIED:20221201T224709Z UID:10000376-1670427000-1670441400@brain.uci.edu SUMMARY:The Cardiac Interatrial Septum & Stroke Risk Symposium DESCRIPTION:Please join the UCI School of Medicine on December 7\, 2022 3:30 – 7:30 p.m. for the Cardiac Interatrial Septum & Stroke Risk Symposium \nThis event will be held via zoom URL:https://brain.uci.edu/event/the-cardiac-interatrial-septum-stroke-risk-symposium/ LOCATION:Zoom\, Irvine\, CA\, 92697\, United States CATEGORIES:Community,Faculty,Scientific,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/12/unnamed.jpg ORGANIZER;CN="UCI School of Medicine%2C Department of Anatomy &%3B Neurobiology":MAILTO:jdiazalo@uci.edu, lgng@hs.uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20230105T110000 DTEND;TZID=America/Los_Angeles:20230105T120000 DTSTAMP:20260421T192340 CREATED:20230102T202546Z LAST-MODIFIED:20230102T202654Z UID:10000379-1672916400-1672920000@brain.uci.edu SUMMARY:C. Dirk Keene\, M.D.\, Ph.D. DESCRIPTION:Co-sponsored by UCI MIND and UCI Center for Neural Circuit Mapping. \nDr. Keene is the Nancy and Buster Alvord Endowed Chair in Neuropathology\, Professor of Pathology\, Adjunct Associate Professor of Ophthalmology and Neurological Surgery\, Director of the Neuropathology Division\, and Leader of the Neuropathology and Targeted Molecular Testing Core at the University of Washington. Dr. Keene is Board Certified in Anatomic Pathology and Neuropathology and regularly attends on each of the clinical neuropathology subspecialties (neurosurgical\, neuromuscular\, ophthalmic\, and autopsy) for UW Medicine. URL:https://brain.uci.edu/event/c-dirk-keene-m-d-ph-d/ LOCATION:Natural Sciences 1114\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/01/keene.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20230117T110000 DTEND;TZID=America/Los_Angeles:20230117T120000 DTSTAMP:20260421T192340 CREATED:20220921T150554Z LAST-MODIFIED:20221206T194546Z UID:10000339-1673953200-1673956800@brain.uci.edu SUMMARY:Elizabeth Head\, Ph.D. DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nWhat we can learn about Alzheimer disease from people with Down syndrome \nJoin the CNLM in a hybrid colloquium featuring Dr. Elizabeth Head\, professor of pathology at UC Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription:  Virtually all people with Down syndrome develop Alzheimer disease neuropathology by the time they are 40 years of age.  Interestingly\, the first signs of cognitive decline may not occur until after 50 years of age\, and some people reach their 60’s without clinical decline.  By examining the brains of people with Down syndrome across the lifespan we can understand the order of events in the development of Alzheimer disease\, including when and where cerebrovascular changes and neuroinflammation occur.  Learning about the sequence of events of Alzheimer disease pathogenesis in Down syndrome will allow us to design prevention and treatment interventions.  Information learned from people with Down syndrome may in turn\, help us promote successful aging in this vulnerable group and may be translated to all people at risk of Alzheimer disease. URL:https://brain.uci.edu/event/elizabeth-head-ph-d/ LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/liz-head-web-3x2-1-e1663772850539.jpg ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT END:VCALENDAR