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DTSTART;TZID=America/Los_Angeles:20221007T100000
DTEND;TZID=America/Los_Angeles:20221007T110000
DTSTAMP:20260421T111837
CREATED:20220929T160851Z
LAST-MODIFIED:20220929T161201Z
UID:10000353-1665136800-1665140400@brain.uci.edu
SUMMARY:Serena M. Dudek\, PhD
DESCRIPTION:Join the Department of Anatomy and Neurobiology in a virtual seminar featuring Dr. Serena M. Dudek \, Deputy Chief and Neurobiology Laboratory and Principal Investigator of the National Institute of Environmental Health Sciences.
URL:https://brain.uci.edu/event/serena-m-dudek-phd/
LOCATION:Virtual Event
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-8-e1664467912680.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221007T120000
DTEND;TZID=America/Los_Angeles:20221007T130000
DTSTAMP:20260421T111837
CREATED:20221004T205910Z
LAST-MODIFIED:20221004T210115Z
UID:10000355-1665144000-1665147600@brain.uci.edu
SUMMARY:BME Seminar Series: How does neuronal activity protect the cortex from stroke?
DESCRIPTION:Abstract: Stroke is the fifth leading cause for death in the U.S. and No. 1 cause for long term disability. Traditionally\, stroke has been studied in animal models using cellular and molecular techniques\, but little attention has been paid to neuronal activity. In this talk\, I will describe surprising findings in a rat model of ischemic stroke relating sensory stimulation-evoked neuronal activity and stroke. Depending on delivery timing\, sensory stimulation-evoked neuronal activity can protect the cortex from impending damage or exacerbate the damage. I will further elucidate the neuronal and vascular mechanisms underlying the protection and exacerbation processes and describe our accumulating evidence that neuronal activity and cortical structure-function relationship are pivotal players in understanding ischemic stroke outcome. \nBiography: Ron D. Frostig is a professor of neurobiology and behavior and biomedical engineering at UCI. He received his bachelor’s degree in biology and his master’s degree in neurobiology from the Hebrew University\, Israel. He received his doctorate in neuroscience at UCLA\, and was a postdoctoral research scholar in neurobiology at the Rockefeller University. His lab’s major research interests include basic and pre-clinical studies of neocortical structure and function with an emphasis on plasticity.
URL:https://brain.uci.edu/event/bme-seminar-series-how-does-neuronal-activity-protect-the-cortex-from-stroke/
LOCATION:McDonnell Douglas Engineering Auditorium\, 314 Los Trancos Drive\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/FrostigLab-Logo-v7.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221011T100000
DTEND;TZID=America/Los_Angeles:20221011T110000
DTSTAMP:20260421T111837
CREATED:20220929T154800Z
LAST-MODIFIED:20220929T154800Z
UID:10000351-1665482400-1665486000@brain.uci.edu
SUMMARY:Sean Foxley\, PhD
DESCRIPTION:Join the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Sean Foxley of the University of Chicago.
URL:https://brain.uci.edu/event/sean-foxley-phd/
LOCATION:CA
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-6.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221019T120000
DTEND;TZID=America/Los_Angeles:20221019T160000
DTSTAMP:20260421T111837
CREATED:20221005T155834Z
LAST-MODIFIED:20221005T155935Z
UID:10000356-1666180800-1666195200@brain.uci.edu
SUMMARY:UC Irvine Neuropolitics Symposium
DESCRIPTION:Cognitive Decline and Political Leadership \nJoin the UCI Center for Neuropolitics in a virtual symposium to discuss cognitive decline among politicians. \nCognitive deterioration of politicians (including diminished memory\, impaired decision-\nmaking\, mood alterations\, and dementia) is a critical emerging issue. This Symposium\nwill address the current state and future directions of assessment of cognitive function\nand decline among politicians. As professions such as law and medicine are addressing\ncognitive effects of age\, their insights may inform development of the proper strategy\nwithin politics. \n  \nClick here to view the symposium agenda
URL:https://brain.uci.edu/event/uc-irvine-neuropolitics-symposium/
LOCATION:Virtual Event
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221025T100000
DTEND;TZID=America/Los_Angeles:20221025T110000
DTSTAMP:20260421T111838
CREATED:20220929T155114Z
LAST-MODIFIED:20221018T171916Z
UID:10000352-1666692000-1666695600@brain.uci.edu
SUMMARY:Li Zhang\, Ph.D.
DESCRIPTION:“Neural circuits for valence coding\, emotional states\, and motivated behaviors” \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Li Zhang of USC Medical School. \nAbstract: \nThe topic is about our recent studies on neural circuits in the medial preoptic area (MPOA) of the hypothalamus. MPOA plays a critical role in parental and prosocial behaviors via subpopulations of its GABAergic neurons. We now show that MPOA can be more generally viewed to serve as a critical hub to mediate both negative and positive emotional states and related behaviors through its glutamatergic and GABAergic neurons\, respectively\, with the former encoding extremely negative valence and mediating anxiety-like behaviors\, and the latter\, oppositely\, encoding positive valence and producing rewarding effects.  I will discuss the circuitry underlying how MPOA coordinately and antagonistically mediates behaviors related to different emotional states.
URL:https://brain.uci.edu/event/li-zhang-ph-d-2/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-7.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221025T120000
DTEND;TZID=America/Los_Angeles:20221025T130000
DTSTAMP:20260421T111838
CREATED:20220929T163455Z
LAST-MODIFIED:20221014T155243Z
UID:10000354-1666699200-1666702800@brain.uci.edu
SUMMARY:NextGen Epilepsy Seminar: Jessie Buth and Christos Lisgaras
DESCRIPTION:Join the UCI Epilepsy Research Center in a virtual seminar of their NextGen Epilepsy Seminar Series featuring Jessie Buth\, PhD Student of the Novitch Lab at UCLA and Christos Lisgaras\, PhD\, Postdoctoral Fellow of the Scharfman Lab at the Nathan S. Kline Institute for Psychiatric Research. \nThe seminar will be hosted by Robert Hunt\, PhD and will feature Jessie Buth presenting Investigating the Role of KDM6B in Human Brain Development and Autism Spectrum Disorder Using Stem Cell Models and Christos Lisgaras presenting Deciphering the Role of Hippocampal Area CA2 in Temporal Lobe Epilepsy Using Closed-Loop Optogenetics. 
URL:https://brain.uci.edu/event/nextgen-epilepsy-seminar-jessie-buth-and-christos-lisgaras/
LOCATION:CA
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/jessieButh-Christos-Lisgaras-01.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221025T130000
DTEND;TZID=America/Los_Angeles:20221025T140000
DTSTAMP:20260421T111838
CREATED:20220929T151034Z
LAST-MODIFIED:20220929T151034Z
UID:10000349-1666702800-1666706400@brain.uci.edu
SUMMARY:Rajendra Morey\, MD\, MS
DESCRIPTION:Leveraging Team Science at a Global Scale to Investigate the Neurobiology of PTSD \nJoin the Conte Center @ UCI for a virtual seminar featuring Dr. Rajendra Morey\, Professor of Psychiatry and Behavioral Sciences at Duke University.
URL:https://brain.uci.edu/event/rajendra-morey-md-ms/
LOCATION:Virtual Event
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/Rajendra-Morey-Headshot.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221028T110000
DTEND;TZID=America/Los_Angeles:20221028T120000
DTSTAMP:20260421T111838
CREATED:20221027T192301Z
LAST-MODIFIED:20221027T192301Z
UID:10000368-1666954800-1666958400@brain.uci.edu
SUMMARY:Patrick J. Lao\, PhD
DESCRIPTION:Please join the UCI Center for Aging Research in Down Syndrome (CFAR-DS) Oct. 28 at 11 am PT  for their Seminar Series presentationtitled Alzheimer’s disease and vascular neuroimaging in adults with Down syndrome\, presented by Patrick J. Lao\, PhD. \nPatrick J. Lao\, PhD is an Assistant Professor of Neurology Sciences at the Taub Institute\, Sergeivsky Center\, and Department of Neurology at Columbia University. He earned his Ph.D. at the University of Wisconsin-Madison in Medical Physics and completed his postdoctoral training at Columbia University in vascular MRI and applied cross-cultural neuropsychology. His research uses multimodal neuroimaging and plasma-based biomarkers to study Alzheimer’s disease. Areas of interest include applying these methods to adults with Down syndrome and in community-based settings. \nThis event will take place via Zoom: \n\n\n\n\n\n\n\n\n\n\nhttps://ucihealth.zoom.us/j/92151970794?pwd=NkMxbWh2aklXWFU4K1hsRUZqOEpKZz09 \nMeeting ID: 921 5197 0794\nPasscode: 954508
URL:https://brain.uci.edu/event/patrick-j-lao-phd/
LOCATION:Virtual Event
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/Patrick-Lau-Headshot.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221104T140000
DTEND;TZID=America/Los_Angeles:20221104T150000
DTSTAMP:20260421T111838
CREATED:20221027T154020Z
LAST-MODIFIED:20221027T154020Z
UID:10000361-1667570400-1667574000@brain.uci.edu
SUMMARY:Takaki Komiyama\, PhD
DESCRIPTION:Motor cortex circuits for learned movements \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Takaki Komiyama\, Professor and Vice Chair of the Department of Neurobiology at UC San Diego. \nThis hybrid seminar will be taking place in the Interdisciplinary Science and Engineering Building (ISEB)2020 & Telecast via Zoom. \n \nAbstract: \nMotor cortex circuits are highly plastic\, enabling adaptive control and learning of body movements. I will discuss two projects. In the first project\, we studied the spatial and functional specificity of synaptogenesis that occurs during motor learning. This was done by longitudinal functional imaging of dendritic spines followed by correlated electron microscopy. In the second project\, we are investigating the roles of motor cortex ensemble activity in the control of learned movements. This is done by population calcium imaging combined with holographic two-photon optogenetic stimulation of neural ensembles.
URL:https://brain.uci.edu/event/takaki-komiyama-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221108T100000
DTEND;TZID=America/Los_Angeles:20221108T110000
DTSTAMP:20260421T111838
CREATED:20221027T162454Z
LAST-MODIFIED:20221027T162454Z
UID:10000362-1667901600-1667905200@brain.uci.edu
SUMMARY:Trygve Bakken\, Ph.D.
DESCRIPTION:Cellular diversity and evolutionary specializations in human neocortex \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Trygve Bakken\, Assistant Investigator at the Allen Institute for Brain Science in a hybrid seminar.
URL:https://brain.uci.edu/event/trygve-bakken-ph-d/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-3.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221108T110000
DTEND;TZID=America/Los_Angeles:20221108T120000
DTSTAMP:20260421T111838
CREATED:20220922T151235Z
LAST-MODIFIED:20221005T181006Z
UID:10000340-1667905200-1667908800@brain.uci.edu
SUMMARY:Alyson Zalta\, Ph.D
DESCRIPTION:Exploring morning light therapy as a novel treatment for traumatic stress \nCNLM Colloquium UCI Spotlight Series \nJoin the CNLM in a hybrid colloquium featuring Dr. Alyson Zalta\, Associate Professor of Psychological Science at UC Irvine. \nDescription: \nTrauma contributes to a wide variety of mental health problems including posttraumatic stress disorder (PTSD)\, depression\, anxiety\, substance use\, and suicidality. Although front-line psychotherapies and pharmacotherapies exist for traumatic stress\, evidence suggests that many individuals fail to receive treatment\, remain symptomatic despite treatment\, or drop out of treatment before its conclusion. Uptake of these treatments is poor for several reasons including stigma\, avoidance\, unpleasant side effects\, and poor accessibility. New treatments are needed for traumatic stress that can overcome these critical barriers to care while targeting the underlying biological mechanisms of the pathology. Morning light treatment has good potential as a novel non-invasive\, low risk\, scalable treatment for traumatic stress. Evidence suggests that morning light may improve traumatic stress by reducing reactivity in the amygdala\, a brain region implicated in the pathophysiology of PTSD and anatomically linked to circadian photoreceptors in the eye. This seminar will describe the results of a randomized pilot trial that provides initial proof-of-concept that light treatment can improve traumatic stress and preliminary results from an ongoing randomized clinical trial aimed at evaluating the brain mechanisms underlying morning light therapy for traumatic stress. \n  \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/alyson-zalta-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221109T160000
DTEND;TZID=America/Los_Angeles:20221109T170000
DTSTAMP:20260421T111838
CREATED:20221027T165046Z
LAST-MODIFIED:20221027T165046Z
UID:10000365-1668009600-1668013200@brain.uci.edu
SUMMARY:Jennifer Gelinas\, MD\, PhD
DESCRIPTION:EpiCenter Seminar Series\nJoin the UCI Epilepsy Research Center for a hybrid seminar featuring Dr. Jennifer Gelinas\, Assistant Professor of Neurology from Columbia University.
URL:https://brain.uci.edu/event/jennifer-gelinas-md-phd/
LOCATION:CA
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-5.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221117T100000
DTEND;TZID=America/Los_Angeles:20221117T110000
DTSTAMP:20260421T111838
CREATED:20221027T164057Z
LAST-MODIFIED:20221027T164113Z
UID:10000364-1668679200-1668682800@brain.uci.edu
SUMMARY:Yongsoo Kim\, PhD
DESCRIPTION:Neuronal and non-neuronal cell type mapping in the mouse brain \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Yongsoo Kim\, Associate Professor from the Department of Neural and Behavioral Sciences\, College of Medicine from Penn State.
URL:https://brain.uci.edu/event/dr-yongsoo-kim/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-2.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221117T160000
DTEND;TZID=America/Los_Angeles:20221117T170000
DTSTAMP:20260421T111838
CREATED:20221027T165601Z
LAST-MODIFIED:20221027T165601Z
UID:10000366-1668700800-1668704400@brain.uci.edu
SUMMARY:Daniel Vogt\, PhD
DESCRIPTION:Join the UCI Epilepsy Research Center in a hybrid seminar featuring Dr. Daniel Vogt\, Assistant Professor of Pediatrics and Human Development at Michigan State University.
URL:https://brain.uci.edu/event/daniel-vogt-phd/
LOCATION:CA
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-6.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221205T100000
DTEND;TZID=America/Los_Angeles:20221205T110000
DTSTAMP:20260421T111838
CREATED:20221128T232720Z
LAST-MODIFIED:20221201T175724Z
UID:10000375-1670234400-1670238000@brain.uci.edu
SUMMARY:Georg F. Striedter\, Ph.D.
DESCRIPTION:Evolutionary Conservation versus Change in Brains and Other Biological Systems \n\n\n\nComparative neuroanatomists in recent years have made great progress in delineating the conserved “Bauplan” of vertebrate brains. However\, brains also evolved some major “new” brain regions that do not fit neatly into the conserved Bauplan view. In particular\, it appears that ray-finned fishes and amniotes have independently evolved a dorsal pallium\, which comprises the neocortex in mammals. Even for homologous brain areas\, changes in connectivity have been common – and often convergent between distantly related species\, such as primates and birds. To expand our understanding of brain evolution\, consider an analogy to evolving molecular systems. In this analogy\, highly conserved genes (including “human disease genes”) correspond to conserved brain regions\, whereas genetic losses and gains correspond to the loss and gain of major brain regions. Moreover\, molecular pathways and interactomes are analogous to neuroanatomical circuits; they\, too\, exhibit significant variation\, nicely captured by the phrase “genetic rewiring.” Because of this molecular variation\, the systems-level function(s) of individual genes and proteins can vary significantly over evolutionary time. This “causal drift” makes it difficult to extrapolate from “simple systems” to more complex networks\, and from model species to humans. Analogs of causal drift in molecular networks have been suggested also for neuronal networks (e.g. neocorticalization)\, but they have not been studied thoroughly. Filling that knowledge gap would be worthwhile.
URL:https://brain.uci.edu/event/evolutionary-conservation-versus-change-in-brains-and-other-biological-systems-featuring-georg-f-striedter-ph-d/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB)\, 4020 (Telecast via Zoom)\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/11/Georg-F.-Striedter-PhD-Headshot.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221207T153000
DTEND;TZID=America/Los_Angeles:20221207T193000
DTSTAMP:20260421T111838
CREATED:20221201T212943Z
LAST-MODIFIED:20221201T224709Z
UID:10000376-1670427000-1670441400@brain.uci.edu
SUMMARY:The Cardiac Interatrial Septum & Stroke Risk Symposium
DESCRIPTION:Please join the UCI School of Medicine on December 7\, 2022 3:30 – 7:30 p.m. for the Cardiac Interatrial Septum & Stroke Risk Symposium \nThis event will be held via zoom
URL:https://brain.uci.edu/event/the-cardiac-interatrial-septum-stroke-risk-symposium/
LOCATION:Zoom\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/12/unnamed.jpg
ORGANIZER;CN="UCI School of Medicine%2C Department of Anatomy &amp%3B Neurobiology":MAILTO:jdiazalo@uci.edu, lgng@hs.uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230105T110000
DTEND;TZID=America/Los_Angeles:20230105T120000
DTSTAMP:20260421T111838
CREATED:20230102T202546Z
LAST-MODIFIED:20230102T202654Z
UID:10000379-1672916400-1672920000@brain.uci.edu
SUMMARY:C. Dirk Keene\, M.D.\, Ph.D.
DESCRIPTION:Co-sponsored by UCI MIND and UCI Center for Neural Circuit Mapping. \nDr. Keene is the Nancy and Buster Alvord Endowed Chair in Neuropathology\, Professor of Pathology\, Adjunct Associate Professor of Ophthalmology and Neurological Surgery\, Director of the Neuropathology Division\, and Leader of the Neuropathology and Targeted Molecular Testing Core at the University of Washington. Dr. Keene is Board Certified in Anatomic Pathology and Neuropathology and regularly attends on each of the clinical neuropathology subspecialties (neurosurgical\, neuromuscular\, ophthalmic\, and autopsy) for UW Medicine.
URL:https://brain.uci.edu/event/c-dirk-keene-m-d-ph-d/
LOCATION:Natural Sciences 1114\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/01/keene.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230117T110000
DTEND;TZID=America/Los_Angeles:20230117T120000
DTSTAMP:20260421T111838
CREATED:20220921T150554Z
LAST-MODIFIED:20221206T194546Z
UID:10000339-1673953200-1673956800@brain.uci.edu
SUMMARY:Elizabeth Head\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nWhat we can learn about Alzheimer disease from people with Down syndrome \nJoin the CNLM in a hybrid colloquium featuring Dr. Elizabeth Head\, professor of pathology at UC Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription:  Virtually all people with Down syndrome develop Alzheimer disease neuropathology by the time they are 40 years of age.  Interestingly\, the first signs of cognitive decline may not occur until after 50 years of age\, and some people reach their 60’s without clinical decline.  By examining the brains of people with Down syndrome across the lifespan we can understand the order of events in the development of Alzheimer disease\, including when and where cerebrovascular changes and neuroinflammation occur.  Learning about the sequence of events of Alzheimer disease pathogenesis in Down syndrome will allow us to design prevention and treatment interventions.  Information learned from people with Down syndrome may in turn\, help us promote successful aging in this vulnerable group and may be translated to all people at risk of Alzheimer disease.
URL:https://brain.uci.edu/event/elizabeth-head-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/liz-head-web-3x2-1-e1663772850539.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230117T160000
DTEND;TZID=America/Los_Angeles:20230117T170000
DTSTAMP:20260421T111838
CREATED:20230105T171315Z
LAST-MODIFIED:20230105T171315Z
UID:10000382-1673971200-1673974800@brain.uci.edu
SUMMARY:Anastasios Tzingounis\, Ph.D.
DESCRIPTION:Join the UCI Epilepsy Research Center in a hybrid seminar featuring Professor Anastasios Tzingounis from the Department of Physiology & Neurobiology at the University of Connecticut. \nOf Mice and KCNQ Channels: Lessons Learned from Animal Models
URL:https://brain.uci.edu/event/anastasios-tzingounis-ph-d/
LOCATION:SSIHI Palmer Family Research and Conference Room\, Rm 2608\, 856 Health Sciences Rd. Rm 2608\, Irvine\, CA\, 92617\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/01/Tzingounis1crop3-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230120T120000
DTEND;TZID=America/Los_Angeles:20230120T133000
DTSTAMP:20260421T111838
CREATED:20221201T224341Z
LAST-MODIFIED:20221201T224749Z
UID:10000377-1674216000-1674221400@brain.uci.edu
SUMMARY:Liberals\, Conservatives\, and the Political Brain: fMRI Studies of Political Ideology
DESCRIPTION:Please join the UCI Center for Neuropolitics Friday\, January 20\, 2023 from 12:00 to 1:30 p.m. for their lecture series\, Liberals\, Conservatives\, and the Political Brain: fMRI Studies of Political Ideology
URL:https://brain.uci.edu/event/liberals-conservatives-and-the-political-brain-fmri-studies-of-political-ideology/
LOCATION:Zoom\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/12/unnamed-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230124T110000
DTEND;TZID=America/Los_Angeles:20230124T120000
DTSTAMP:20260421T111838
CREATED:20221014T203259Z
LAST-MODIFIED:20221222T160759Z
UID:10000359-1674558000-1674561600@brain.uci.edu
SUMMARY:Lisa Flanagan\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nRegulation of early neural development by glycosylation \nJoin the CNLM in a hybrid colloquium featuring Dr. Lisa Flanagan\, Associate Professor of Neurology at UC Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nDeciphering how neural stem cells function in early development to generate the cerebral cortex will help us better understand normal and disrupted brain formation and organization. We used neural stem cells\, genetic mouse models\, and innovative engineering approaches to uncover a novel role for glycosylation in directing early neural development. N-linked glycosylation of the neural stem cell plasma membrane controls neuronal and astrocytic differentiation\, likely through regulation of cell surface protein binding to extracellular ligands. Increased formation of cell surface highly-branched N-glycans promotes astrocyte generation whereas loss of these glycans disrupts neuron differentiation in vitro and in vivo. Glycosylation plays a critical and previously unrecognized role in cell differentiation and early brain development and may help to explain cellular responses to extracellular cues.
URL:https://brain.uci.edu/event/lisa-flanagan-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-2.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230125T150000
DTEND;TZID=America/Los_Angeles:20230125T160000
DTSTAMP:20260421T111838
CREATED:20230120T170322Z
LAST-MODIFIED:20230120T170322Z
UID:10000386-1674658800-1674662400@brain.uci.edu
SUMMARY:Conor Liston\, Ph.D.\, M.D.
DESCRIPTION:Conor Liston\, Ph.D.\, M.D.\nAssociate Professor\nFeil Family Brain and Mind Research Institute/Psychiatry\, Weill\nCornell Medicine \nWednesday\, Jan. 25\, 2023\n3:00 – 4:00 pm PST\nHerklotz Conference Center* \nProbing and rescuing dysfunctional brain circuits in depression
URL:https://brain.uci.edu/event/conor-liston-ph-d-m-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/01/Conor-Liston-Headshot.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230131T110000
DTEND;TZID=America/Los_Angeles:20230131T120000
DTSTAMP:20260421T111838
CREATED:20220922T151720Z
LAST-MODIFIED:20221222T024742Z
UID:10000342-1675162800-1675166400@brain.uci.edu
SUMMARY:Javier Diaz Alonso\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nChasing the AMPAR slot(s). Multiple mechanisms modulate synaptic strength. \nJoin the CNLM in a hybrid colloquium featuring Dr. Javier Diaz Alonso\, Assistant Professor of Anatomy and Neurobiology at UC Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nLong-term potentiation (LTP) of excitatory synapses is essential for multiple forms of learning and memory formation. Pioneering work from CNLM members and others led to a model for NMDAR-dependent LTP where synaptic strengthening depends on the recruitment of AMPA receptors to the postsynapse. Despite decades of research\, the molecular mechanisms underlying the activity-dependent insertion of AMPA receptors at synapses\, and specifically which regions in the receptor complex are required for trafficking and docking\, are not fully understood. In the past few years\, we have assessed the role played by different protein domains of the AMPAR complex in these processes\, focusing on: i) the sequence diverse intracellular AMPAR C-tails\, ii) the extracellular ATDs\, which protrude into the synaptic cleft and iii) the AMPAR auxiliary proteins TARPs\, which interact with synaptic scaffolds. Our recent and ongoing work is revealing an important role for all of these 3 elements\, yet our data suggests that they play different roles in different synapses and control different AMPAR-dependent processes. I will discuss our unpublished work\, in collaboration with other CNLM labs\, dissecting novel molecular mechanisms modulating the activity-dependent synaptic accumulation and subsynaptic positioning of AMPARs to support novelty processing\, learning and memory formation.
URL:https://brain.uci.edu/event/javier-diaz-alonso-ph-d-2/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/Dr.-Diaz-Alonso-3x2-1-300x200-1.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230207T110000
DTEND;TZID=America/Los_Angeles:20230207T120000
DTSTAMP:20260421T111838
CREATED:20220922T151937Z
LAST-MODIFIED:20230115T095102Z
UID:10000343-1675767600-1675771200@brain.uci.edu
SUMMARY:Aaron Bornstein\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nJoin the CNLM in a hybrid colloquium featuring Dr. Aaron Bornstein\, Assistant Professor of Cognitive Sciences at UC Irvine. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. Description: Reconciling adaptive and maladaptive responses to uncertainty: Data and theory.
URL:https://brain.uci.edu/event/aaron-bornstein-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/06/aaron-bornstein-01-400x267-1.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230214T110000
DTEND;TZID=America/Los_Angeles:20230214T120000
DTSTAMP:20260421T111838
CREATED:20220922T151507Z
LAST-MODIFIED:20221129T194501Z
UID:10000341-1676372400-1676376000@brain.uci.edu
SUMMARY:Kei Igarashi\, Ph.D.
DESCRIPTION:Circuit mechanisms of associative memory in health and Alzheimer’s disease \nCNLM Colloquium UCI Spotlight Series \nJoin the CNLM in a hybrid colloquium featuring Dr. Kei Igarashi\, Associate Professor of Anatomy and Neurobiology at UC Irvine. \nDescription:\n\nMounting evidence shows that dopamine in the striatum is critically involved in reward-based reinforcement learning. However\, it remains unclear how dopamine reward signals influence the entorhinal-hippocampal circuit\, another brain network critical for learning and memory. Using in vivo optogenetic and electrophysiological approaches\, we recently found that dopamine signals from the ventral tegmental area control encoding of cue-reward association rules in the lateral entorhinal cortex (LEC) (Lee et al.\, Nature\, 2021). Our results suggest that LEC represent a cognitive map of abstract task rules\, and LEC dopamine facilitates the incorporation of new memories into this map. I would like to discuss how we can unify the roles of two central\, but previously independent\, players in learning – dopamine and the entorhinal-hippocampal circuit – in future studies. In the second part of the talk\, I will share our results on how neuronal activities in the entorhinal-hippocampal memory circuit are lost in a mouse model of Alzheimer’s disease (Jun et al.\, Neuron\, 2020)\, and discuss how the systems neuroscience approach can contribute to the understanding of Alzheimer’s disease pathogenesis. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/kei-igarashi-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-1.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230228T110000
DTEND;TZID=America/Los_Angeles:20230228T120000
DTSTAMP:20260421T111838
CREATED:20220922T152849Z
LAST-MODIFIED:20230130T200149Z
UID:10000347-1677582000-1677585600@brain.uci.edu
SUMMARY:Georg Striedter\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nWhich model system is “best”?  An argument from toxicology. \nJoin the CNLM in a hybrid colloquium featuring Dr. Georg Striedter\, Professor of Neurobiology and Behavior at UC Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nAs researchers seek to find treatments for various disorders\, they tend to use diverse model systems\, but which models are “best” for a given aim? Dr. Striedter has recently published a book on this topic and\, in this talk\, will discuss the challenges of model system selection from a perspective rarely mentioned at the CNLM\, namely that of toxicology. As toxicologists examine whether a particular compound is toxic to humans\, should they study cultured cells\, mice\, guinea pigs\, monkeys\, or (of course) multiple models? As the number of studied models goes up\, what happens to the risk of obtaining false positives? Which research strategy is most cost effective? These questions have clear analogs when it comes to selecting models for research on human diseases\, neurological or otherwise. Dr. Striedter will discuss these analogies briefly\, using Alzheimer’s disease as a CNLM-relevant example. He intends to leave plenty of room for discussion.
URL:https://brain.uci.edu/event/georg-striedter-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-4.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230321T110000
DTEND;TZID=America/Los_Angeles:20230321T120000
DTSTAMP:20260421T111838
CREATED:20221006T220515Z
LAST-MODIFIED:20230214T170733Z
UID:10000357-1679396400-1679400000@brain.uci.edu
SUMMARY:Pierre Baldi\, Ph.D. - NEW DATE
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nJoin the CNLM in a hybrid colloquium featuring Dr. Pierre Baldi\, Distinguished Professor in the Department of Computer Science and Director of the Institute for Genomics and Bioinformatics at UC Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \n\n\n\nThe quest for how the brain learns \n\n\n\n\n\n\nWe will first showcase two cutting-edge applications of modern Artificial Intelligence (AI) in biomedical imaging and in reasoning. These applications\, as well as most modern AI applications (e.g.\, ChatGPT\, AlphaFold\, AlphaGO\, Google Translate\, Self-Driving Cars) are based on deep learning\, a modern rebranding of neural networks\, or connectionist methods\, dating back to the 1980s\, or even the 1950s.  We will then briefly review the neuroscience-inspired\, tortuous\, historical path that has led to deep learning\, and the key discoveries made along the way\, highlighting the synergies and discrepancies between neuroscience and deep learning. One key conclusion is that approximate gradient descent is essential for learning. However\,  the standard gradient descent algorithm of deep learning called backpropagation  is not biologically-plausible for multiple reasons. We will examine these reasons one-by-one and identify biologically-plausible solutions for each one of them. In particular\, we will introduce and demonstrate a general class of neural architectures and learning algorithms capable of learning from data in a largely unsupervised and asynchronous manner\, without the need for symmetric connectivity.
URL:https://brain.uci.edu/event/pierre-baldi-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/pierre-baldi-01-400x267-1.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230328T110000
DTEND;TZID=America/Los_Angeles:20230328T120000
DTSTAMP:20260421T111838
CREATED:20220922T152646Z
LAST-MODIFIED:20230314T182415Z
UID:10000346-1680001200-1680004800@brain.uci.edu
SUMMARY:Kevin T. Beier\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nJoin the CNLM in a hybrid colloquium featuring Dr. Kevin T. Beier\, Assistant Professor of Physiology and Biophysics at UC Irvine. \nMolecular mechanisms of memory stability and the molecular and circuit determinants of cocaine addiction \n  \nDescription: \nI will speak on two separate projects in our lab. First\, we have uncovered the molecular mechanism by which administration of the Zeta Inhibitory Peptide (ZIP) causes memory loss. While it was previously believed that ZIP administration perturbs memory stability through disruption of constitutive kinase activity\, recent studies have cast doubt on this hypothesis. However\, ZIP’s effects on memory stability are robust\, raising the question of what the actual mechanism is by which ZIP exerts its function. We have identified the basic molecular and pathways engaged by ZIP\, and use this information to identify an inhibitor that\, together with ZIP\, enables bidirectional modulation of synaptic plasticity. Second\, we are exploring the biological factors that influence the behavioral response to the administration of drugs of abuse. Some individuals that take drugs of abuse are susceptible to developing dependence\, while others are resilient. The fundamental source of this variation is not understood. We will discuss our work implicating circuit- and molecular-level changes in the globus pallidus that facilitate individual differences in response to cocaine administration\, and share the identification of a novel small molecule compound\, isolated from rosemary\, that blunts drug reward and volitional intake. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/kevin-t-beier-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-3.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230404T110000
DTEND;TZID=America/Los_Angeles:20230404T120000
DTSTAMP:20260421T111838
CREATED:20220926T155054Z
LAST-MODIFIED:20230320T182242Z
UID:10000348-1680606000-1680609600@brain.uci.edu
SUMMARY:Megan Peters\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nJoin the CNLM in a hybrid colloquium featuring Dr. Megan Peters\, Assistant Professor of Cognitive Science at UC Irvine. \nNeurocomputational approaches to the study of perceptual awareness \nDescription: When our brains process sensory information\, they transform it into a coherent\, conscious experience that we use to drive adaptive decisions and learning. In this talk I will describe several ongoing lines of research in my group that focus on understanding the neural and computational substrates of our subjective sense of the world around us. Specifically\, separating the study of phenomenology from the study of signal processing capacity is challenging\, so our group has been focusing on how the study of metacognitive evaluation (confidence judgements in our perceptual decisions) may shine light on these processes. Using a combination of behavior/psychophysics\, computational modeling\, noninvasive neuroimaging\, and machine learning in humans\, we seek to understand how the brain is capable of efficiently using sensory information and how this ability relates to our qualitative\, phenomenal experiences. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/megan-peters-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/Megan-Peters.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230426T080000
DTEND;TZID=America/Los_Angeles:20230430T170000
DTSTAMP:20260421T111838
CREATED:20230329T164104Z
LAST-MODIFIED:20230329T164104Z
UID:10000398-1682496000-1682874000@brain.uci.edu
SUMMARY:LEARNMEM2023
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory for the 2023 International Conference on Learning and Memory (LEARNMEM™2023) on April 26-30\, 2023 in Huntington Beach\, CA. The Conference will be held in celebration of the 40th Anniversary of the Center for the Neurobiology of Learning and Memory (CNLM). \nLEARNMEM™2023 will feature keynote talks by distinguished speakers\, scientific symposia\, lightning talks\, open papers\, poster sessions as well as professional development and networking opportunities. \nThe conference will have a substantial impact on the field by accelerating the pace of team science and providing a unique networking opportunity for the next generation of leaders in neuroscience.
URL:https://brain.uci.edu/event/learnmem2023/
LOCATION:Waterfront Beach Resort\, 21100 Pacific Coast Highway\, Huntington Beach\, CA\, 92648\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/03/LearnMem2023RegistrationBanner-01-1536x831-1.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
END:VCALENDAR