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TZID:America/Los_Angeles
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240206T110000
DTEND;TZID=America/Los_Angeles:20240206T120000
DTSTAMP:20260421T123838
CREATED:20231009T213853Z
LAST-MODIFIED:20231205T181600Z
UID:10000431-1707217200-1707220800@brain.uci.edu
SUMMARY:Elizabeth A. Buffalo\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Elizabeth A. Buffalo\, professor and chair of physiology and biophysics at the University of Washington. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nNeural Dynamics of Memory Formation in the Primate Hippocampus  \n \nDescription:  \nOur understanding of the hippocampus has been framed by two landmark discoveries: the discovery by Scoville and Millner that hippocampal damage causes profound and persistent amnesia and the discovery by O’Keefe and Dostrovsky of hippocampal place cells in rodents. However\, it has been unclear to what extent spatial representations are present in the primate brain and how to reconcile these representations with the known mnemonic function of this region. I will discuss a series of experiments that have examined neural activity in the hippocampus in monkeys performing behavioral tasks including foraging and spatial memory tasks in a virtual environment. These data demonstrate that behavioral task structure has a significant influence on hippocampal activity\, with neurons responding to all salient events within the task. Taken together\, these data are consistent with the idea that activity in the hippocampus tracks ongoing experience in support of memory formation.
URL:https://brain.uci.edu/event/elizabeth-buffalo-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/beth-buffalo-250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240215T110000
DTEND;TZID=America/Los_Angeles:20240215T120000
DTSTAMP:20260421T123838
CREATED:20240202T182333Z
LAST-MODIFIED:20240202T182333Z
UID:10000477-1707994800-1707998400@brain.uci.edu
SUMMARY:Garret Anderson\, PhD
DESCRIPTION:The department of Anatomy & Neurobiology will host guest speaker Garret Anderson from UC Riverside\, who will give a talk on ““Latrophilin cell-type specific expression and implications for neural circuit development”
URL:https://brain.uci.edu/event/garret-anderson-phd/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/02/Capture.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240305T110000
DTEND;TZID=America/Los_Angeles:20240305T120000
DTSTAMP:20260421T123838
CREATED:20231009T215006Z
LAST-MODIFIED:20240229T212335Z
UID:10000432-1709636400-1709640000@brain.uci.edu
SUMMARY:J. David Jentsch\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. J. David Jentsch\, Distinguished Professor and Chair of psychology at Binghamton University. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nDiversity to the rescue: Identifying novel molecular regulators of addiction liability
URL:https://brain.uci.edu/event/j-david-jentsch-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/jjentsch-2.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240312T110000
DTEND;TZID=America/Los_Angeles:20240312T120000
DTSTAMP:20260421T123838
CREATED:20231009T215405Z
LAST-MODIFIED:20240130T163208Z
UID:10000433-1710241200-1710244800@brain.uci.edu
SUMMARY:Christian Bravo Rivera\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Christian Bravo Rivera\, assistant professor of psychiatry\, anatomy\, and neurobiology. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nNeural circuits mediating reward approach and punishment avoidance conflict  \nReward is often present in risky environments\, requiring individuals to weigh the benefits of rewards against the associated risks. There are individuals that are unable to choose an appropriate response during risky reward opportunities and thus exhibit extreme avoidance or risky behaviors that can severely impair quality of life or endanger people. It is therefore necessary to characterize how neurons mediate reward approach and threat avoidance conflict. Here\, we adapted the platform-mediated avoidance conflict task (Bravo-Rivera et al 2014; Bravo-Rivera et al 2021)\, such that water-deprived mice could nose-poke for a light-signaled water reward and avoid a tone-signaled foot-shock by stepping onto a safety platform away from the reward port. Optogenetic activation of GABAergic neurons in the ventral pallidum invigorated reward approach at the expense of receiving shocks. Photometry recordings of glutamatergic neurons in the ventral pallidum and in the lateral habenula during conflict revealed that these structures promote avoidance and become inhibited during conflicted reward approach. These results suggest that a pallidal-habenula circuit mediates motivational conflict. We also compared behavioral conflict in male and female mice. Interestingly\, females stepped on the platform earlier than males after tone onset and took longer to leave the platform after tone offset. Males received more shocks than females and received more water reward than females by the end conflict training. Moreover\, females exhibited more tone-induced freezing and exhibited more frequent darting than males. These results suggest that females exhibit more avoidance behavior and less reward approach than males in the face of approach/avoidance conflict.
URL:https://brain.uci.edu/event/christian-bravo-rivera-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/christian-bravo-rivera250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240314T110000
DTEND;TZID=America/Los_Angeles:20240314T120000
DTSTAMP:20260421T123838
CREATED:20240208T235302Z
LAST-MODIFIED:20240209T161652Z
UID:10000494-1710414000-1710417600@brain.uci.edu
SUMMARY:Krishna Jayant\, PhD
DESCRIPTION:The department of Anatomy & Neurobiology will host guest speaker Dr. Krishna Jayant\, an assistant professor from Purdue University. \nA translaminar space-time code supports touch-evoked traveling waves \nTraveling waves in mammalian cortex mediate vital aspects of animal cognition\, such as stimuli perception and working memory. Theoretical results suggest that these waves preserve timing and are critical for plasticity across long-range neural circuits. Therefore\, revealing the circuit mechanisms underlying sensory-evoked traveling waves is critical to understanding the neural basis of sensory perception. In this talk\, I will describe our recent efforts in using 2D nanotextured transparent ECoG style electrodes to map circuits orchestrating wave dynamics. Specifically\, by simultaneously mapping local-field-potentials and cellular ensemble dynamics (via 2P calcium imaging)\, we will describe the circuit features tied to traveling waves under active and passive whisker touch. We will show that in awake mice\, both passive and active whisker touch elicited traveling waves within and across barrels\, with both an early and late component lasting hundreds of milliseconds.  Strikingly\, wave dynamics reflected the value of the tactile stimulus\, and was found to be shaped by reinforcement learning. We will also describe how the late wave component is i) strongly modulated by motor feedback\, ii) complements a sparse ensemble pattern across layer 2/3 which we resolved via a balanced-state network model with distributed top-down feedback\, and iii) aligns with regenerative Layer 5 apical dendritic Ca2+ spikes. Our results establish a model in which translaminar spacetime patterns\, organized by motor cortical feedback\, sculpt touch-evoked traveling waves.
URL:https://brain.uci.edu/event/krishna-jayant-phd/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/02/Untitled-design-48.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240315T120000
DTEND;TZID=America/Los_Angeles:20240315T131500
DTSTAMP:20260421T123838
CREATED:20240131T220057Z
LAST-MODIFIED:20240131T220057Z
UID:10000472-1710504000-1710508500@brain.uci.edu
SUMMARY:Presidential Leadership and Disability
DESCRIPTION:The age of presidential candidates has become a salient concern\, but age is not the only physical factor that should concern citizens. Presidents can also suffer various forms of illness\, both physical and psychological. This talk highlights the nature of these concerns and how we might work to mitigate their impact on political outcomes. \nFree registration is open now: https://uci.zoom.us/webinar/register/WN_m5HtweYgSh6t9sGnAa_hOQ#/registration \nFor more details\, please visit: https://sites.uci.edu/centerforneuropolitics/
URL:https://brain.uci.edu/event/presidential-leadership-and-disability/
LOCATION:Zoom Webinar
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Neuropolitics-Social-Ad_FridayMarch5th2024_-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240409T100000
DTEND;TZID=America/Los_Angeles:20240409T110000
DTSTAMP:20260421T123838
CREATED:20240125T235047Z
LAST-MODIFIED:20240327T223638Z
UID:10000469-1712656800-1712660400@brain.uci.edu
SUMMARY:Xiaoyin Chen\, Ph.D.
DESCRIPTION:Understanding cortical organization using in situ sequencing \nThe UCI Center for Neural Circuit Mapping will host Xiaoyin Chen\, PhD\, assistant investigator of the Barcoded Connectomics Program at the  Allen Institute.
URL:https://brain.uci.edu/event/xiaoyin-chen-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-15.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240409T110000
DTEND;TZID=America/Los_Angeles:20240409T120000
DTSTAMP:20260421T123838
CREATED:20231009T215849Z
LAST-MODIFIED:20240213T192635Z
UID:10000434-1712660400-1712664000@brain.uci.edu
SUMMARY:Nanthia Suthana\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Nanthia Suthana\, associate professor-in-residence at the University of California\, Los Angeles. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nUnraveling Memories on the Go: Insights from Mobile Intracranial EEG Recordings in Humans \n \nDescription: \nRecent technology enables the study of deep brain activity during memory phenomena in ambulatory humans navigating through real or virtual environments. Through these methods\, we have shown dynamic modulation of hippocampal\, entorhinal\, and amygdala activity by factors like movement speed\, eye movements\, emotional valence and memory success. This presentation will provide an overview of these findings and explore potential clinical applications\, particularly in treating neuropsychiatric disorders such as post-traumatic stress disorder.
URL:https://brain.uci.edu/event/nanthia-suthana-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/nanthia-suthana-profile.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240411T110000
DTEND;TZID=America/Los_Angeles:20240411T123000
DTSTAMP:20260421T123838
CREATED:20240206T192557Z
LAST-MODIFIED:20240327T222339Z
UID:10000492-1712833200-1712838600@brain.uci.edu
SUMMARY:Joshua Johansen\, PhD
DESCRIPTION:The department of Anatomy & Neurobiology will host guest speaker Dr. Joshua Johansen from the RIKEN Center for Brain Science \nConstructing Emotional Representations in the Brain \nDescription: \nInnately aversive experiences profoundly alter brain processing to produce emotional states which coordinate physiological and behavioral responses and instruct memory formation. However\, more complex emotions occur through an evaluation of the environment in the context of past experiences and the current physiological condition of the organism. My lab studies the neural circuits and cell coding mechanisms which translate aversive experiences into simple and complex emotional states in the brain to regulate memory formation and guide behavior. I will describe our recent work identifying a brainstem neural circuit which conveys both external-sensory and internal-motor features of innately aversive experiences to create a sensorimotor state in the amygdala for producing aversive memory formation. Contrasting with this bottom-up circuit\, we’ve also found that the medial prefrontal cortex encodes more complex emotional states by building an internal associative model to perform emotional inference through top-down projections to the amygdala. These studies support a new hierarchical circuit model of emotion in which sensory\, bodily and cognitive factors shape neural processing across distributed neural circuits to adaptively and flexibly control defensive responding and memory formation.
URL:https://brain.uci.edu/event/anatomy-neurobiology-seminar-dr-joshua-johansen/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/02/j.johansen.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240416T110000
DTEND;TZID=America/Los_Angeles:20240416T120000
DTSTAMP:20260421T123838
CREATED:20240327T215151Z
LAST-MODIFIED:20240327T221827Z
UID:10000513-1713265200-1713268800@brain.uci.edu
SUMMARY:Semir Zeki\, FMedSci\, FRS
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for an online event featuring Dr. Semir Zeki\, professor of neuroaesthetics at University College London. This event will be held virtually via Zoom. \nThe science of beauty \n \nThe experience of beauty is something that we all seek and are prepared to expend considerable energy and much money in trying to acquire. But what does it entail neurobiologically? If it is a subjective experience\, can it ever be measured? Are there\, or can there be\, any set of characteristics that render objects beautiful\, irrespective of culture and upbringing?I will address these questions from a neurobiological perspective. I will show that there cannot be a single characteristic or a single set of characteristics that can render any and every object beautiful because of the way in which our brains are organized to perceive the world. I will also show that there are\, in the perception of different attributes such as visual motion\, faces and bodies\, criteria which are not culture or education bound which can be said to enhance their beauty and to be critical to the experience of beauty when viewing them. Finally\, I will show that all works that are experienced as beautiful\, regardless of source (i.e. whether visual or musical or highly cognitive – as with mathematical beauty)\, have\, as a correlate\, activity in a specific part of the reward system of the emotional brain\, although the neural route used to reach that part of the brain varies\, depending on what is perceived. The intensity of activity there bears a quantitative relationship to the declared intensity of the experience of beauty\, thus enabling us to detect and quantify the neural correlates of a subjective experience.
URL:https://brain.uci.edu/event/semir-zeki-fmedsci-frs/
LOCATION:Zoom\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/03/Semir-Zeki.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240423T110000
DTEND;TZID=America/Los_Angeles:20240423T120000
DTSTAMP:20260421T123838
CREATED:20231009T220619Z
LAST-MODIFIED:20240313T230915Z
UID:10000436-1713870000-1713873600@brain.uci.edu
SUMMARY:Laura Colgin\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Laura Colgin\, professor of neuroscience at the University of Texas at Austin. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nHippocampal place cell responses to spatial and non-spatial information \n \nDescription: \nThe hippocampus is a key brain network for episodic memory. Place cells are neurons in the hippocampus that fire in specific spatial locations known as place fields. This spatially selective firing is thought to code the “where” component of episodic memory. Yet\, episodic memories contain nonspatial information also. This talk will present results showing how different populations of hippocampal place cells respond to nonspatial aspects of an experience\, such as social stimuli or motivational context. The results may help explain how the hippocampus integrates different aspects of an experience into a coherent episodic memory.
URL:https://brain.uci.edu/event/laura-colgin-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/Laura-Colgin.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240430T100000
DTEND;TZID=America/Los_Angeles:20240430T110000
DTSTAMP:20260421T123838
CREATED:20240201T201916Z
LAST-MODIFIED:20240327T225747Z
UID:10000475-1714471200-1714474800@brain.uci.edu
SUMMARY:Tian Lu\, Ph.D.
DESCRIPTION:Spatially resolved single-cell epigenomics and functional genomics \nThe Center for Neural Circuit Mapping (CNCM) will host Dr. Tian Lu\, a postdoctoral fellow in chemistry and chemical biology at Harvard University.
URL:https://brain.uci.edu/event/tian-lu/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/02/Untitled-design-19.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240430T110000
DTEND;TZID=America/Los_Angeles:20240430T120000
DTSTAMP:20260421T123838
CREATED:20231009T221147Z
LAST-MODIFIED:20240325T155921Z
UID:10000437-1714474800-1714478400@brain.uci.edu
SUMMARY:Chioma Okeoma\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a virtual event featuring Dr. Chioma Okeoma\, associate professor of pathology\, microbiology\, and immunology at the New York Medical College. This event will be held virtually via Zoom. \nExtracellular condensates – do we have to worry about them?
URL:https://brain.uci.edu/event/chioma-okeoma-ph-d/
LOCATION:Virtual via Zoom\, CA
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/Okeoma_Headshot-250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240503T120000
DTEND;TZID=America/Los_Angeles:20240503T131500
DTSTAMP:20260421T123838
CREATED:20240416T160932Z
LAST-MODIFIED:20240416T171250Z
UID:10000525-1714737600-1714742100@brain.uci.edu
SUMMARY:Darren Schreiber\, PhD
DESCRIPTION:Join the UCI Center for Neuropolitics for their lecture with Darren Schreiber\, PhD\, JD\, Senior Lecturer in Politics at the University of Exeterin. \nGuess Who’s Coming to Dinner in 2024? How Partisan Identity Politics is Taking Over America \nThe past twenty years have demonstrated the role of biology in our political predispositions\, with evidence from twin studies\, genetics\, and brain imaging. Recent trends have highlighted political polarization on an emotional\, identity-driven level where the other side is seens as a hated enemy. The consequences have ranged from increasing dissatisfaction with democracy to a rise in violent extremism.
URL:https://brain.uci.edu/event/darren-schreiber-phd/
LOCATION:Zoom Webinar
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/04/Untitled-design-21.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240507T110000
DTEND;TZID=America/Los_Angeles:20240507T120000
DTSTAMP:20260421T123838
CREATED:20231009T221552Z
LAST-MODIFIED:20240206T183816Z
UID:10000438-1715079600-1715083200@brain.uci.edu
SUMMARY:Daeyeol Lee\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Daeyeol Lee\, Bloomberg Distinguished Professor of neuroscience\, psychological and brain sciences at Johns Hopkins University. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nPlaying Games in the Brain \n \nDescription: \nSocial animals face the challenging task of predicting the actions of others. Game theory formalizes the decision making in social settings\, and reinforcement learning theories can be applied to understand the cognitive processes involved in iterative social interactions. In this talk\, I will review the neural correlates of such iterative learning in primate prefrontal cortex during simple competitive games\, such as the rock-paper-scissors\, as well as a more cognitively complex board game\, such as the 4-in-a-row. The results from these experiments demonstrate the advantage of formal games in deciphering the neurocomputational mechanisms of decision making and planning.
URL:https://brain.uci.edu/event/daeyeol-lee-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/daeyeol.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240509T110000
DTEND;TZID=America/Los_Angeles:20240509T140000
DTSTAMP:20260421T123838
CREATED:20240430T193453Z
LAST-MODIFIED:20240430T221544Z
UID:10000532-1715252400-1715263200@brain.uci.edu
SUMMARY:2024 CNLM Award Ceremony
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for the 2024 CNLM Awards Ceremony. \nThe CNLM offers awards to exceptional postdoctoral researchers\, graduate trainees\, undergraduates students\, faculty\, and alumni.  Student and trainee awardees will be invited to present their work in brief Elevator Pitch format to the UCI academic community and the public at our annual CNLM Awards Ceremony. \n \nFor more information\, please visit: https://cnlm.uci.edu/awards/
URL:https://brain.uci.edu/event/2024-cnlm-award-ceremony/
LOCATION:Irvine Improv\, 527 Spectrum Center Dr\, 527 Spectrum Center Dr\, 92618\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/04/For-more-information-please-visit-httpscnlm.uci_.eduawards.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240516T110000
DTEND;TZID=America/Los_Angeles:20240516T120000
DTSTAMP:20260421T123838
CREATED:20240409T211009Z
LAST-MODIFIED:20240409T213139Z
UID:10000518-1715857200-1715860800@brain.uci.edu
SUMMARY:Samantha Butler\, PhD
DESCRIPTION:“Revisiting the role(s) of netrin1 in the establishment of spinal cord circuitry.” \nThe department of Developmental and Cell Biology is hosting Dr Samantha Butler in their weekly seminar series. Dr Butler is the Eleanor I. Leslie Chair in Pioneering Brain Research; a professor in the UCLA Department of Neurobiology as well as the vice chair for Equity\, Diversity\, and Inclusion; a member of the UCLA Eli and Edythe Broad Center of Regenerative Medicine & Stem Cell Research\, the Intellectual & Developmental Disabilities Research Center\, and the David Geffen School of Medicine at UCLA.
URL:https://brain.uci.edu/event/samantha-butler-phd/
LOCATION:4201 Natural Sciences II\, Irvine\, CA 92697\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/04/Untitled-design.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240521T110000
DTEND;TZID=America/Los_Angeles:20240521T120000
DTSTAMP:20260421T123838
CREATED:20231009T211617Z
LAST-MODIFIED:20240123T184610Z
UID:10000430-1716289200-1716292800@brain.uci.edu
SUMMARY:Brad Postle\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nControlling the Contents of Visual Working Memory \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Brad Postle\, professor of psychology at the University of Wisconsin-Madison. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nTwo hallmarks of working memory are flexibility — ability to mentally juggle multiple pieces of information\, prioritizing what’s relevant for the task immediately at hand while also keeping potentially important but currently unprioritized information in an accessible state — and updateability — allowing for the rapid replacement of the no-longer-needed with the newly relevant. This talk will explore these two aspects of the control of working memory at the levels of algorithmic operation and neural implementation. Specifically\, although parsimony holds that “deprioritization” and “removal” might be accomplished via the same mechanism\, I will draw on neuroimaging (EEG and fMRI)\, computational (RNN\, RL)\, and behavioral data to argue for two distinct\, novel\, processes for controlling the contents of WM: the transformation of representational geometries as a function of priority; and the top-down hijacking of mechanisms of adaptation to accomplish active removal. This work may generalize to broader questions\, such as of how we control the moment-to-moment contents of conscious awareness\, and how we diagnose and treat disorders of thought.
URL:https://brain.uci.edu/event/brad-postle-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/Postle_forPsychWeb250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240522T090000
DTEND;TZID=America/Los_Angeles:20240522T150000
DTSTAMP:20260421T123838
CREATED:20240401T041115Z
LAST-MODIFIED:20240401T041115Z
UID:10000514-1716368400-1716390000@brain.uci.edu
SUMMARY:EpiCenter Symposium
DESCRIPTION:The 2024 EpiCenter Symposium will celebrate the 20th year of the NIH T32 program in epilepsy research. Talks will feature speakers working to solve important problems related to epilepsy in the laboratory\, the clinic and the community.
URL:https://brain.uci.edu/event/epicenter-symposium/
LOCATION:Sue Gross Auditorium\, 854 Health Sciences Rd\, Irvine\, 92617\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/03/epicenter.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240604T100000
DTEND;TZID=America/Los_Angeles:20240604T110000
DTSTAMP:20260421T123838
CREATED:20240531T163110Z
LAST-MODIFIED:20240531T163530Z
UID:10000538-1717495200-1717498800@brain.uci.edu
SUMMARY:Bomin Sun\, M.D.\, Ph.D.
DESCRIPTION:Combined BNST and NAc stimulation for medical refractory depression: RCT and mechanism \nThe Center for Neural Circuit Mapping is hosting a seminar by Dr. Bomin Sun\, professor of neurosurgery at the Shanghai Jiao Tong University Rui Jin Hospital.
URL:https://brain.uci.edu/event/bomin-sun-md-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/05/Bomin-Sun_250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240613T100000
DTEND;TZID=America/Los_Angeles:20240613T110000
DTSTAMP:20260421T123838
CREATED:20240531T164220Z
LAST-MODIFIED:20240531T164220Z
UID:10000539-1718272800-1718276400@brain.uci.edu
SUMMARY:Johnathan Tang\, Ph.D.
DESCRIPTION:Integrative approaches to tackling experience-dependent outcomes \nThe Center for Neural Circuit Mapping is hosting a seminar by Dr. Johnathan Tang\, assistant professor of pediatrics at the University of Washington.
URL:https://brain.uci.edu/event/johnathan-tang-ph-d/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/05/Johnathan_Tang_250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240618T160000
DTEND;TZID=America/Los_Angeles:20240618T170000
DTSTAMP:20260421T123838
CREATED:20231009T221940Z
LAST-MODIFIED:20240531T165028Z
UID:10000439-1718726400-1718730000@brain.uci.edu
SUMMARY:Catherine Hartley\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory and Conte Center@UCI for a hybrid event featuring Dr. Catherine Hartley\, associate professor of psychology at New York University. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nInteractive development of reinforcement learning and episodic memory \n \nHighlighting the fundamentally interactive nature of learning and memory\, recent studies in adults have demonstrated that the same quantitative learning signals that inform value computation during reinforcement learning also modulate how information is prioritized and represented in episodic memory. While both reinforcement learning and episodic memory processes exhibit qualitative shifts from childhood to adulthood\, how the interactions between these neurocognitive systems might change over development remains virtually unexplored. In this talk\, I will present studies that leverage computational modeling to characterize age-related shifts in how reinforcement learning computations influence the content and granularity of memory\, and how memory\, in turn\, informs value-based choices. I will discuss how these processes may support adaptive behavior at different developmental stages.
URL:https://brain.uci.edu/event/catherine-hartley-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/catherine_hartley_250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240709T100000
DTEND;TZID=America/Los_Angeles:20240709T110000
DTSTAMP:20260421T123838
CREATED:20240531T164916Z
LAST-MODIFIED:20240625T143634Z
UID:10000540-1720519200-1720522800@brain.uci.edu
SUMMARY:Dorote Lucci\, Ph.D.
DESCRIPTION:The Center for Neural Circuit Mapping will host guest speaker Dr. Dorote Lucci\, Chair of the Global Conference on Advancing Mental Health. \nExploring the Intersection of AI\, Neuroscience\, and Transformative Learning: A Whole-Person Perspective from Transpersonal Psychology
URL:https://brain.uci.edu/event/dorote-lucci-ph-d/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/05/lucci.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241004T080000
DTEND;TZID=America/Los_Angeles:20241004T180000
DTSTAMP:20260421T123838
CREATED:20240827T171255Z
LAST-MODIFIED:20241001T173341Z
UID:10000574-1728028800-1728064800@brain.uci.edu
SUMMARY:2024 Second Annual Symposium for the Center for Neurotherapeutics
DESCRIPTION:The purpose of the Symposium will be to familiarize attendees with the UCI Center for\nNeurotherapeutics and introduce attendees to the exciting translational\nneuroscience research happening right on our campus and in labs across the country. We\nhope that attendees will: \n\nLearn about the vision that drives us at the UCI Center for Neurotherapeutics and our\nongoing effort to advance drug development on campus.\nBecome acquainted with cutting-edge approaches being applied to develop innovative\nmodels and novel therapeutic solutions for neurological diseases. Lecture topics will\ninclude drug discovery and high-throughput screening methods to identify rational\ndrug targets. Experts from diverse disciplines will explain how they are tackling the\nchallenge of delivering small molecules and biological agents across the blood-brain\nbarrier.\nAppreciate the many opportunities for cross-disciplinary interaction and collaboration\nin this field. Our number one core value at the UCI Center for Neurotherapeutics is to\npromote collaboration across campus\, especially between faculty in the physical\nsciences and the biological sciences. We believe that only by combining such multi-\ndisciplinary expertise and diverse perspectives will it be possible to unlock new\navenues of discovery and accelerate progress toward developing meaningful solutions\nfor therapy development.\n\nOur exceptional line-up of guest speakers and UCI faculty speakers include: \n\nAnabella Villalobos (Biogen); Neurological/Rare Disease Therapies\nDonna Huryn (University of Pennsylvania); Academic Drug Discovery Challenges\nEthan Lippmann (Vanderbilt); siRNA Brain Delivery via Albumin\nSu Guo (UC San Francisco); GPCR Targeting in Parkinson’s\nHang Lu (Georgia Tech); Microtechnology &amp; AI in Drug Screening\n Errol Arkilic (UC Irvine); Beall Applied Innovation\nLeslie Thompson (UC Irvine); Huntington’s Disease Treatment Advances\nJennifer Prescher (UC Irvine); Nature-Inspired Imaging Tools\nChristopher Hughes (UC Irvine); Blood-Brain Barrier Neurovascular Model\nMelanie Cocco (UC Irvine); Voxelotor for Red Blood Cell Modulation\n\nWhether you are a student\, postdoctoral trainee\, faculty member\, or staff member\, we\nencourage you to join us\, so please mark your calendars! \nRegistration is free! \nPlease register by Friday\, September 27\, 2024.
URL:https://brain.uci.edu/event/2024-second-annual-symposium-for-the-center-for-neurotherapeutics/
LOCATION:Samueli Integrative Health Institute Sue Gross Auditorium\, 856 Health Sciences Quad\, Irvine\, 92697\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/08/Picture1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241011T130000
DTEND;TZID=America/Los_Angeles:20241011T170000
DTSTAMP:20260421T123838
CREATED:20240925T222627Z
LAST-MODIFIED:20240925T223103Z
UID:10000592-1728651600-1728666000@brain.uci.edu
SUMMARY:Masakazu Agetsuma\, Ph.D.
DESCRIPTION:The Center for Neural Circuit Mapping will host guest speaker Dr. Masakazu Agetsuma\, Associate Professor of Neuroscience at the National Institute for Physiological Sciences\, Japan \n “Activity-dependent organization of prefrontal hub-networks for associative learning and signal transformation” \nAssociative learning is crucial for adapting to environmental changes. Interactions among neuronal populations involving the dorso-medial prefrontal cortex (dmPFC) in rodents are proposed to regulate associative memory. Although neural network remodeling is generally believed to underlie learning and memory\, how this process occurs to store and process associative memory remains one of the most critical open questions in the field. To tackle this question\, we developed a pipeline for longitudinal two-photon imaging and mathematical dissection of neural population activities in mouse dmPFC during fear-conditioning procedures\, enabling us to detect learning-dependent changes in the dmPFC information coding and network topology. After confirming that the dmPFC contributes to the expression of the conditioned responses (CR) by chemogenetic silencing\, we recorded neural population activities and analyzed them by regularized regression methods and graphical modeling. We found that fear conditioning drove dmPFC reorganization to generate a neuronal ensemble encoding CR\, which was characterized by enhanced internal coactivity and functional connectivity. Importantly\, neurons strongly responding to unconditioned stimuli during fear conditioning subsequently became hubs of this novel network and revealed enhanced association with conditioned stimuli (CS) specifically in the CR ensemble\, which may work as an information-processing neural network implementing CS-triggered CR. Altogether\, we demonstrate learning-dependent dynamic modulation of population coding structured on the activity-dependent formation of the hub network within the dmPFC. features reflecting the biomechanical constraints and evolutionary origins of these motor control systems.”
URL:https://brain.uci.edu/event/masakazu-agetsuma-phd/
LOCATION:Plumwood House Room 166\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697-3800\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-9.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241016T193000
DTEND;TZID=America/Los_Angeles:20241016T203000
DTSTAMP:20260421T123838
CREATED:20240724T191849Z
LAST-MODIFIED:20240927T164530Z
UID:10000556-1729107000-1729110600@brain.uci.edu
SUMMARY:Lisa Feldman Barrett\, Ph.D.
DESCRIPTION:The McGaugh-Gerard Lecture on Learning and Memory will host guest speaker Dr. Lisa Feldman Barrett\, University Distinguished Professor of Psychology at Northeastern University. \nThree Lessons About the Brain \n  \nEver wonder how your brain really works? Join us for the 3rd Annual McGaugh-Gerard Lecture on Learning and Memory by Dr. Lisa Feldman Barrett\, an author and expert in psychology and neuroscience\, as she breaks down three key ideas about the brain’s inner workings. In this talk\, you’ll learn: \n\nHow your brain’s most important job is keeping your body running smoothly.\nHow your brain is constantly predicting what will happen next rather than reacting to the world.\nHow feeling and thinking and even seeing follow from your brain’s plan for action; your brain prepares your behavior first and creates your lived experience in the process.\n\nDr. Barrett will show how these brain functions affect how you feel\, how you think\, and what you do.
URL:https://brain.uci.edu/event/lisa-feldman-barrett-ph-d/
LOCATION:Irvine Barclay Theater\, 4242 Campus Drive\, Irvine\, CA\, 92612\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/07/feldman-300.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241029T100000
DTEND;TZID=America/Los_Angeles:20241029T110000
DTSTAMP:20260421T123838
CREATED:20241007T214557Z
LAST-MODIFIED:20241007T214557Z
UID:10000600-1730196000-1730199600@brain.uci.edu
SUMMARY:Yang Yang\, PhD
DESCRIPTION:UCI Epilepsy Research Center will host guest speaker Dr. Yang Yang\, Jack and Barbara McCoy Associate Professor from Purdue University\, for their EpiCenter Seminar. \n“SCN2A related autism and epilepsy: from mouse and hiPSC models to genetic medicine”
URL:https://brain.uci.edu/event/yang-yang-phd/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/10/thumbnail_Yang-profile-photo-F-e1728337550531.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241105T110000
DTEND;TZID=America/Los_Angeles:20241105T120000
DTSTAMP:20260421T123838
CREATED:20240924T165621Z
LAST-MODIFIED:20241009T174633Z
UID:10000583-1730804400-1730808000@brain.uci.edu
SUMMARY:Jeffrey Krichmar\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Jeffrey Krichmar\, Professor of Cognitive Sciences at the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nBiologically inspired robot navigation \nWe take inspiration from recent neurophysiological findings to create a flexible navigation system for mobile robots.  In the first part of my talk\, I will present a neuromorphic path planning algorithm inspired by place cell behavior and experience-dependent plasticity. Our navigation system utilizes a spiking neural network wavefront planner and E-prop learning to concurrently map and plan paths in large\, complex environments. We incorporate a novel method for mapping which\, when combined with the spiking wavefront planner\, allows for adaptive planning by selectively considering combining costs. The learning is continuous and does not require retraining due to changes in the environment. The system is tested on a mobile robot platform in an outdoor environment with obstacles and varying terrain.  On real and simulated paths\, our system outperforms state-of-the-art robot path planners. The spiking wavefront planner is compatible with neuromorphic hardware and could be used for applications requiring low size weight and power. In the second part of my talk\, I will discuss how we seamlessly move between global perspectives and first-person perspectives and why this is important for navigation\, memory formation\, and other cognitive tasks. To understand how a neural system might carry out these computations\, we used variational autoencoders (VAEs) to reconstruct first-person perspectives from global map perspectives\, and vice versa. Many latent variables in our model had similar responses to those seen in neuron recordings\, including place cells\, head direction tuning\, and encoding distance to objects. These results could advance our understanding of how brain regions support viewpoint linkages and transformations. Currently\, we are combining these two modeling approaches into a unified biologically inspired navigation system that can handle dynamic environments.
URL:https://brain.uci.edu/event/jeffrey-krichmar-ph-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241112T110000
DTEND;TZID=America/Los_Angeles:20241112T120000
DTSTAMP:20260421T123838
CREATED:20240924T171223Z
LAST-MODIFIED:20241009T174711Z
UID:10000584-1731409200-1731412800@brain.uci.edu
SUMMARY:J. Zoe Klemfuss\, Ph.D.
DESCRIPTION:  \n \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. J. Zoe Klemfuss\, Associate Professor of Psychological Sciences at the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nChildren’s memory reports in legal contexts \nMillions of US children are centrally involved in legal investigations each year. They may be questioned as suspected victims or witnesses or in other impactful legal proceedings like custody determinations. As one chilling example\, over 3 million children are the subjects of child protective services disposition due to suspected maltreatment annually. In some of the most heinous crimes against children such as child sexual abuse\, children’s statements may be the only available evidence. These crimes rarely have other witnesses and because disclosure is routinely delayed\, physical evidence is rare as well. My colleagues and I have been examining ways we can help children to give accurate and detailed memory reports of their legally-relevant experiences. In this talk\, I will focus on how we’ve been considering child\, interviewer\, and contextual factors as we examine 1) children’s reports of event time and sequence and 2) interviewer-child rapport and support\, and their implications for children’s legal statements.
URL:https://brain.uci.edu/event/j-zoe-klemfuss-ph-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-1.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241119T110000
DTEND;TZID=America/Los_Angeles:20241119T120000
DTSTAMP:20260421T123838
CREATED:20240925T223533Z
LAST-MODIFIED:20240925T223718Z
UID:10000593-1732014000-1732017600@brain.uci.edu
SUMMARY:Katalin Gothard\, MD\, Ph.D.
DESCRIPTION:The James L. McGaugh Distinguished Seminar will host guest speaker Dr. Katalin Gothard\, Professor of Physiology\, Neurology\, and Neuroscience\, from The University of Arizona \n“A context-dependent switch from sensing to feeling in the primate amygdala” \nTactile signals elicited in the periphery by social and affective touch acquire emotional significance in the brain. As the amygdala processes the valence of all sensory stimuli\, we predicted that the positive valence of grooming would strongly activate the monkey amygdala. To test this hypothesis\, we compared neural activity in the amygdala and the primary somatosensory cortex in response to social grooming and gentle airflow delivered to the same areas of the skin. Neurons in the somatosensory cortex responded to both types of tactile stimuli. In the amygdala\, however\, neurons did not respond to individual grooming sweeps even though grooming elicited autonomic states indicative of positive affect. Instead of responses to individual touch stimuli\, a large proportion of neurons showed enhanced or suppressed baseline firing rates that persisted throughout a grooming bout. These changes were attributed to social context because the presence of the groomer alone could account for increases or decreases in baseline firing rates. It appears\, therefore\, that during grooming\, the amygdala stops responding to external inputs on a short time scale but remains responsive to social context\, and the associated affective states\, on longer time scales. \n 
URL:https://brain.uci.edu/event/katalin-gothard-md-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-10.png
END:VEVENT
END:VCALENDAR