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DTSTART;TZID=America/Los_Angeles:20241210T110000
DTEND;TZID=America/Los_Angeles:20241210T120000
DTSTAMP:20260421T185946
CREATED:20240924T171632Z
LAST-MODIFIED:20241011T171544Z
UID:10000585-1733828400-1733832000@brain.uci.edu
SUMMARY:Anna Leshinskaya\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Anna Leshinskaya\, Assistant Professor of Cognitive Sciences at the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nProcesses of learning and integration to build relational memory in the human brain \nThe human brain naturally uses experience to infer how entities\, attributes\, and events relate to each other\, abilities that are essential for both episodic and semantic memory. Yet\, the learning and inference processes that allow the brain to build relational memory\, across multiple neural circuits and time\, remain poorly specified. In this talk\, I will discuss two sets of findings using human fMRI and temporal relation learning. In the first\, I use computational theories of learning as precise but competing hypotheses for how the brain uses noisy experiential data to infer the strength of relations among visual events and to build relational memory. Results reveal a surprising computational continuity between memory formation and the mechanisms of reinforcement learning and classical conditioning. Furthermore\, neural and behavioral data jointly suggest that the brain supports multiple strategies simultaneously\, and raises the further question of how strategies are selected. In the second finding\, I shed light on how the brain integrates diverse experiences to build knowledge of shared relational structure\, in both classically episodic and semantic brain areas across two time-points. I find that entorhinal cortex\, in particular\, plays a key role in rapid relational integration that complements the role of semantic areas in slower integrative processes. I will raise a number of open future questions regarding the neural mechanisms of relational memory.
URL:https://brain.uci.edu/event/anna-leshinskaya-ph-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-2.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241217T100000
DTEND;TZID=America/Los_Angeles:20241217T110000
DTSTAMP:20260421T185946
CREATED:20241030T182232Z
LAST-MODIFIED:20241125T210044Z
UID:10000620-1734429600-1734433200@brain.uci.edu
SUMMARY:Rui Chen\, PhD
DESCRIPTION:The Center for Neural Circuit Mapping will host guest speaker Dr. Rui Chen\, Professor of Ophthalmology at University of California\, Irvine. \nEstablishing a Comprehensive Cell Atlas of the Human Retina \n\nSingle-cell sequencing has dramatically enhanced the scale and resolution of molecular profiling for tissues and organs. We have recently generated an integrated dual-modal reference atlas of the retina\, the most accessible part of the mammalian central nervous system. We compiled approximately 3.9 million cells from 125 donors\, incorporating data from eight published studies and 2.7 million unpublished data points\, to create a comprehensive Human Retina Cell Atlas (HRCA) identifying over 120 cell types. Our analysis revealed intriguing differences in transcriptomes\, chromatin landscapes\, and gene regulatory networks (GRNs) across various cell types. Additionally\, we modeled changes in gene expression and chromatin accessibility across age\, ancestry\, and tissue regions. This integrated atlas facilitated the fine-mapping of genome-wide association study (GWAS) and expression quantitative trait loci (eQTL) variants. Further improvements to the Version 1 HRCA are planned\, incorporating single-cell spatial transcriptomics and single-cell long-read RNA sequencing\, which will enhance our understanding of retinal function and pathology.
URL:https://brain.uci.edu/event/rui-chen-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) 1200\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/10/Untitled-design-48.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250121T110000
DTEND;TZID=America/Los_Angeles:20250121T120000
DTSTAMP:20260421T185946
CREATED:20240924T172040Z
LAST-MODIFIED:20241115T203301Z
UID:10000586-1737457200-1737460800@brain.uci.edu
SUMMARY:Gyorgy Lur\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Gyorgy Lur\, Associate Professor of Neurobiology and Behavior at the University of California\, Irvine. \nHow stress reorganizes cognitive circuits in the parietal cortex \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/gyorgy-lur-ph-d-2/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-3.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250211T110000
DTEND;TZID=America/Los_Angeles:20250211T120000
DTSTAMP:20260421T185946
CREATED:20240925T230557Z
LAST-MODIFIED:20241202T184542Z
UID:10000594-1739271600-1739275200@brain.uci.edu
SUMMARY:Shahrdad Lotfipour\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Shahrdad Lotfipour\, Associate Professor of Emergency Medicine and Pharmaceutical Sciences at the University of California\, Irvine. \nMolecular neurobiology of adolescent nicotine use \nAdolescence is a critical period for brain development\, particularly in systems underlying reward and addiction. My lab’s research focuses on understanding how genetic and environmental factors interact to influence adolescent nicotine use\, co-morbid substance abuse\, and relapse. Using innovative CRISPR-Cas9-generated rodent models mimicking human genetic variants\, we investigate the molecular\, neurochemical\, and behavioral mechanisms driving nicotine’s effects on reward and relapse. This talk will highlight key findings on the sex- and genotype-dependent influences of the CHRNA6 3′-UTR SNP on dopamine and norepinephrine systems\, behavioral outcomes in nicotine and methamphetamine co-use\, and nicotine-seeking behavior. These insights provide a framework for exploring targeted therapeutic strategies for adolescent substance use. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/shahrdad-lotfipour-ph-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-12.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250218T110000
DTEND;TZID=America/Los_Angeles:20250218T120000
DTSTAMP:20260421T185946
CREATED:20240924T172623Z
LAST-MODIFIED:20240924T172623Z
UID:10000587-1739876400-1739880000@brain.uci.edu
SUMMARY:Lulu Y. Chen\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Lulu Y. Chen\, Associate Professor of Anatomy and Neurobiology at the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/lulu-y-chen-ph-d-2/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-4.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250325T110000
DTEND;TZID=America/Los_Angeles:20250325T120000
DTSTAMP:20260421T185946
CREATED:20240924T173816Z
LAST-MODIFIED:20240924T173957Z
UID:10000588-1742900400-1742904000@brain.uci.edu
SUMMARY:Momoko Watanabe\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Momoko Watanabe\, Assistant Professor of Anatomy and Neurobiology at the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/momoko-watanabe-ph-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-5.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250401T110000
DTEND;TZID=America/Los_Angeles:20250401T120000
DTSTAMP:20260421T185946
CREATED:20240924T174642Z
LAST-MODIFIED:20240924T174922Z
UID:10000589-1743505200-1743508800@brain.uci.edu
SUMMARY:David Reinkensmeyer\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. David Reinkensmeyer\, Professor of Mechanical and Aerospace Engineering at the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/david-reinkensmeyer-ph-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-6.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250422T110000
DTEND;TZID=America/Los_Angeles:20250422T120000
DTSTAMP:20260421T185946
CREATED:20240924T175858Z
LAST-MODIFIED:20240924T175950Z
UID:10000591-1745319600-1745323200@brain.uci.edu
SUMMARY:Katharine Simon\, Ph.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Katharine Simon\, Assistant Professor of Pediatrics at the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/katharine-simon-ph-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-8.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250429T110000
DTEND;TZID=America/Los_Angeles:20250429T120000
DTSTAMP:20260421T185946
CREATED:20240924T175102Z
LAST-MODIFIED:20241002T152017Z
UID:10000590-1745924400-1745928000@brain.uci.edu
SUMMARY:Lauren N. Ross\, Ph.D.\, M.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Lauren N. Ross\, Associate Professor and Logic and Philosophy of Science\nat the University of California\, Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom.
URL:https://brain.uci.edu/event/lauren-n-ross-ph-d-m-d/
LOCATION:Hybrid Event (This event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room)\, 300 Qureshey Research Lab Irvine\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/09/Jeffrey-Krichmar-Ph.D.-7.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250527T100000
DTEND;TZID=America/Los_Angeles:20250527T110000
DTSTAMP:20260421T185946
CREATED:20241030T182458Z
LAST-MODIFIED:20241030T182458Z
UID:10000621-1748340000-1748343600@brain.uci.edu
SUMMARY:Ting Wang\, PhD
DESCRIPTION:The Center for Neural Circuit Mapping will host guest speaker Dr. Ting Wang\, Distinguished Professor of Medicine and Head of Department of Genetics at Washington University School of Medicine. \nTransposable elements and cancer epigenome evolution
URL:https://brain.uci.edu/event/ting-wang-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) 1200\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/10/Untitled-design-47.png
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