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DTSTART;TZID=America/Los_Angeles:20230124T110000
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DTSTAMP:20260418T211633
CREATED:20221014T203259Z
LAST-MODIFIED:20221222T160759Z
UID:10000359-1674558000-1674561600@brain.uci.edu
SUMMARY:Lisa Flanagan\, Ph.D.
DESCRIPTION:CNLM Colloquium UCI Spotlight Series \nRegulation of early neural development by glycosylation \nJoin the CNLM in a hybrid colloquium featuring Dr. Lisa Flanagan\, Associate Professor of Neurology at UC Irvine. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nDeciphering how neural stem cells function in early development to generate the cerebral cortex will help us better understand normal and disrupted brain formation and organization. We used neural stem cells\, genetic mouse models\, and innovative engineering approaches to uncover a novel role for glycosylation in directing early neural development. N-linked glycosylation of the neural stem cell plasma membrane controls neuronal and astrocytic differentiation\, likely through regulation of cell surface protein binding to extracellular ligands. Increased formation of cell surface highly-branched N-glycans promotes astrocyte generation whereas loss of these glycans disrupts neuron differentiation in vitro and in vivo. Glycosylation plays a critical and previously unrecognized role in cell differentiation and early brain development and may help to explain cellular responses to extracellular cues.
URL:https://brain.uci.edu/event/lisa-flanagan-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image-2.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
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DTSTART;TZID=America/Los_Angeles:20230125T150000
DTEND;TZID=America/Los_Angeles:20230125T160000
DTSTAMP:20260418T211633
CREATED:20230120T170322Z
LAST-MODIFIED:20230120T170322Z
UID:10000386-1674658800-1674662400@brain.uci.edu
SUMMARY:Conor Liston\, Ph.D.\, M.D.
DESCRIPTION:Conor Liston\, Ph.D.\, M.D.\nAssociate Professor\nFeil Family Brain and Mind Research Institute/Psychiatry\, Weill\nCornell Medicine \nWednesday\, Jan. 25\, 2023\n3:00 – 4:00 pm PST\nHerklotz Conference Center* \nProbing and rescuing dysfunctional brain circuits in depression
URL:https://brain.uci.edu/event/conor-liston-ph-d-m-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/01/Conor-Liston-Headshot.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
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