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DTSTART;TZID=America/Los_Angeles:20220111T130000
DTEND;TZID=America/Los_Angeles:20220111T140000
DTSTAMP:20260421T133738
CREATED:20211207T184944Z
LAST-MODIFIED:20211207T190340Z
UID:10000289-1641906000-1641909600@brain.uci.edu
SUMMARY:Conte Center Seminar Series - Thomas Kash PhD
DESCRIPTION:Join us Tuesday\, January 11th\, 2022 for a Conte Center@UCI Seminar: “Probing the Role of Serotonin in Alcohol Use Disorders”\, Guest Speaker: Thomas L. Kash PhD from the Department of Pharmacology at the University of North Carolina Chapel Hill.
URL:https://brain.uci.edu/event/conte-center-seminar-series-thomas-kash-phd/
LOCATION:Virtual Event
CATEGORIES:Faculty,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/12/kash_Headshot.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220113T100000
DTEND;TZID=America/Los_Angeles:20220113T110000
DTSTAMP:20260421T133738
CREATED:20211130T202411Z
LAST-MODIFIED:20211130T202411Z
UID:10000287-1642068000-1642071600@brain.uci.edu
SUMMARY:Pascal Kaeser\, MD
DESCRIPTION:Mechanisms for Fast Dopamine Signaling \nPlease join the UCI School of Medicine Department of Anatomy and Neurobiology for a virtual seminar featuring\, Pascal Kaeser\, MD\, Associate Professor of Neurobiology of Harvard Medical School.
URL:https://brain.uci.edu/event/pascal-kaeser-md/
LOCATION:Virtual Event
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/image-2.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20220125T110000
DTEND;TZID=UTC:20220125T120000
DTSTAMP:20260421T133738
CREATED:20210810T002846Z
LAST-MODIFIED:20211018T213414Z
UID:10000257-1643108400-1643112000@brain.uci.edu
SUMMARY:CNLM Colloquium with Melissa Sharpe\, Ph.D.
DESCRIPTION:The CNLM will be hosting\, Dr. Melissa Sharpe\, Assistant Professor of Behavioral Neuroscience at the University of California\, Los Angeles in a colloquium where she will be presenting her latest research. \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n\n\n\n\n\nThe finding that dopamine neurons support intracranial self-stimulation (ICSS) has been taken to suggest that phasic firing of dopamine neurons is reinforcing. This is one of the last findings preventing a move away from the value hypothesis of dopamine. Yet there are almost no studies investigating the cognitive basis of ICSS. We tested how dopamine stimulation is represented in the brain during ICSS. We found that physiological frequencies did not support robust ICSS or promote behavior that would indicate the stimulation was represented as a meaningful reward in a specific or general sense. However\, supraphysiological frequencies supported robust ICSS and this was associated with a representation of the stimulation as a specific sensory event that was capable of acting as a goal to motivate behavior. This demonstrates that dopamine neurons only support ICSS at supraphysiological frequencies\, and in a manner that does not reflect our subjective experience with endogenous firing of dopamine neurons during learning. These data provide important considerations for the interpretation of ICSS when used to interrogate the physiological function of dopamine and other neuronal populations.
URL:https://brain.uci.edu/event/cnlm-colloquium-with-melissa-sharpe-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-3.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220125T110000
DTEND;TZID=America/Los_Angeles:20220125T120000
DTSTAMP:20260421T133738
CREATED:20211130T200220Z
LAST-MODIFIED:20211130T200220Z
UID:10000286-1643108400-1643112000@brain.uci.edu
SUMMARY:CNCM Seminar: Dr. Joshua Trachtenberg
DESCRIPTION:Please join the UCI Center for Neural Circuit Mapping in a seminar featuring Dr. Joshua Trachtenberg of UCLA. \nFor more information\, please visit: https://cncm.som.uci.edu/seminars/
URL:https://brain.uci.edu/event/cncm-seminar-dr-joshua-trachtenberg/
LOCATION:Virtual Event
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/image-1.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20220201T110000
DTEND;TZID=UTC:20220201T120000
DTSTAMP:20260421T133738
CREATED:20210810T003024Z
LAST-MODIFIED:20220128T173525Z
UID:10000258-1643713200-1643716800@brain.uci.edu
SUMMARY:CNLM Colloquium with Barry Setlow\, Ph.D.
DESCRIPTION:Sex\, drugs\, and getting old; influences on decision making and executive functions \nThe CNLM will host Dr. Barry Setlow\, professor of psychiatry at the University of Florida College of Medicine\, in a colloquium where he will present his latest research.
URL:https://brain.uci.edu/event/cnlm-colloquium-with-barry-setlow-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-4.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220208T090000
DTEND;TZID=America/Los_Angeles:20220208T123000
DTSTAMP:20260421T133738
CREATED:20220125T220206Z
LAST-MODIFIED:20220128T171840Z
UID:10000292-1644310800-1644323400@brain.uci.edu
SUMMARY:19th Annual EpiCenter Symposium
DESCRIPTION:19th Annual EpiCenter Symposium Brain Development & Epilepsy \nThe 19th Annual EpCenter Symposium includes keynote speaker Bina Santoro\, PhD\, assistant research scientist at the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University.
URL:https://brain.uci.edu/event/19th-annual-epicenter-symposium/
LOCATION:Virtual Event
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/image-2.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220208T110000
DTEND;TZID=America/Los_Angeles:20220208T120000
DTSTAMP:20260421T133738
CREATED:20220128T195043Z
LAST-MODIFIED:20220128T214210Z
UID:10000295-1644318000-1644321600@brain.uci.edu
SUMMARY:Carlos Portera Cailliau\, MD
DESCRIPTION:Cortical interneuron hypofunction in Fragile X Syndrome \nThe Department of Neurobiology and Behavior will host Carlos Portera Cailliau\, from the Department of Neurology & Neurobiology of the University of California\, Los Angeles\, for a James L. McGaugh Distinguished Lecture. \n  \n\nAbstract \n\nCortical circuit dysfunction is a primary pathophysiology in neurodevelopmental disorders (NDDs). Considering how symptoms in NDDs/autism become apparent in toddlers\, circuit changes must emerge very early in cortical development.  Over the last decade\, developmental differences in cortical synaptic dynamics\, neuronal adaptation\, and network synchrony have been reported in the Fmr1 knockout (KO) mouse model of Fragile X Syndrome (FXS)\, a prototypical NDD.  In addition\, the density\, maturity and activity of parvalbumin (PV) cortical interneurons are all reduced in Fmr1 KO mice and in other autism mouse models.  We find that the density of PV neurons in S1 is reduced in both juvenile and adult Fmr1 KO mice\, as well as in post-mortem tissue from human FXS cases.  Furthermore\, the density and the firing of Nkx2.1-expressing interneuron precursors are also reduced in early Fmr1 KO mice. Increasing MGE-derived interneuron activity using excitatory DREADDs significantly increases the density of PV cells at P15. Moreover\, increasing PV cell firing in Fmr1 KO mice with a novel allosteric modulator of Kv3.1 channels improves deficits in the tuning and the adaptation of excitatory neurons in S1 to repetitive whisker stimulation.
URL:https://brain.uci.edu/event/carlos-portera-cailliau-md/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/image-4.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220210T100000
DTEND;TZID=America/Los_Angeles:20220210T110000
DTSTAMP:20260421T133738
CREATED:20220125T221957Z
LAST-MODIFIED:20220128T214002Z
UID:10000293-1644487200-1644490800@brain.uci.edu
SUMMARY:Bruce Herring\, Ph.D.
DESCRIPTION:Cell-specific expression of SAP97 links augmented glutamatergic synapse function to Schizophrenia \nJoin the Department of Anatomy & Neurobiology for a virtual seminar featuring Bruce Herring\, PhD\, assistant professor of neurobiology at the University of Southern California.
URL:https://brain.uci.edu/event/bruce-herring-phd/
LOCATION:Virtual Event
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/image-3.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220215T120000
DTEND;TZID=America/Los_Angeles:20220215T170000
DTSTAMP:20260421T133738
CREATED:20220106T204621Z
LAST-MODIFIED:20220128T172653Z
UID:10000290-1644926400-1644944400@brain.uci.edu
SUMMARY:13th Annual Emerging Scientists Symposium
DESCRIPTION:Join REMIND and UCI MIND for the 13th Annual Emerging Scientists Symposium featuring keynote speaker\, Cynthia Lemere\, PhD\, associate professor at the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital at Harvard Medical School.
URL:https://brain.uci.edu/event/13th-annual-emerging-scientists-symposium/
LOCATION:UCI Student Event Center\, 311 W Peltason Dr # A\, Irvine\, CA 92697\, Doheny Beach Meeting Room\, 311 W Peltason Dr # A\, Irvine\, CA 92697\, Irvine\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/13th-Annual-Emerging-Scientists-Symposium1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220215T130000
DTEND;TZID=America/Los_Angeles:20220215T140000
DTSTAMP:20260421T133738
CREATED:20211207T184929Z
LAST-MODIFIED:20220128T173445Z
UID:10000288-1644930000-1644933600@brain.uci.edu
SUMMARY:William A. Carlezon Jr. Ph.D.
DESCRIPTION:Enduring effects of early developmental immune activation \nThe Conte Center@UCI Seminar Series will feature guest speaker William A. Carlezon Jr. Ph.D.\, professor of psychiatry at Harvard Medical School.
URL:https://brain.uci.edu/event/conte-center-seminar-series-william-a-carlezon-jr-phd/
LOCATION:Virtual Event
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/12/Carlezon_Headshot-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220222T160000
DTEND;TZID=America/Los_Angeles:20220222T170000
DTSTAMP:20260421T133738
CREATED:20220209T223630Z
LAST-MODIFIED:20220209T223906Z
UID:10000298-1645545600-1645549200@brain.uci.edu
SUMMARY:UCI MSTP Distinguished Lecture Series Talk | Speaker: Garret Stuber \, Ph.D. on Tuesday\, February 22nd 2022
DESCRIPTION:Wednesday\, February 22\, 2022 \nNeurocircuits for Motivation and Reward featuring Guest Speaker\, Garret Stuber\, PhD\nProfessor\, Department of Anesthesiology and Pain Medicine\, University of Washington \n4 – 5 p.m. PT \nFree to attend. RSVP encouraged.\nVirtual/Hybrid Event\nTelecast via Zoom\, and in-person in Tamkin F110 \n\nOrganized by: MSTP students Dhruba Banerjee\, and Heechul Jun \nEvent Contacts: Heechul Jun | heechulj@hs.uci.edu
URL:https://brain.uci.edu/event/uci-mstp-distinguished-lecture-series-talk-speaker-garret-stuber-ph-d-on-tuesday-february-22nd-2022/
LOCATION:Virtual/Hybrid Event (Telecast via Zoom\, and in-person in Tamkin F110)\, Tamkin F110 Academy Wy\, Irvine\, CA\, 92617\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/Seminar-Ad-Twitter.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220301T100000
DTEND;TZID=America/Los_Angeles:20220301T110000
DTSTAMP:20260421T133738
CREATED:20220222T165026Z
LAST-MODIFIED:20220222T165026Z
UID:10000301-1646128800-1646132400@brain.uci.edu
SUMMARY:CNCM Seminar: Dr. Edward Zagha
DESCRIPTION:Neural mechanisms of target stimulus selection and distractor stimulus suppression \nJoin the UCI Center for Neural Circuit Mapping in a Hybrid (Virtual and In-Person) Seminar featuring Edward Zagha\, MD\, PhD from UC Riverside. \nThose who wish to attend in person will receive details upon registration. \nAbstract: \n Goal-directed behavior requires the ability to respond to task-relevant target stimuli (selection) while inhibiting responses to extraneous distractor stimuli (suppression). To better understand the neural mechanisms underlying these processes\, we trained mice in an operant whisker detection task in which they learned to respond to brief stimuli in one whisker field (target) and ignore identical stimuli in the opposite whisker field (distractor). We subsequently performed a range of neuronal recording and perturbation experiments in expert mice while they were performing this selective detection task. In this talk\, I will present data from three studies related to the differential neural processing of target and distractor signals. First\, I will demonstrate the robust attenuation of distractor-evoked responses downstream of primary somatosensory cortex (Aruljothi et al.\, 2020). Second\, I will show that frontal cortex and dorsolateral striatum have highly similar task-related neuronal representations\, and yet make drastically different functional contributions to target selection and distractor suppression. Third\, I will provide evidence for a novel mechanism by which top-down signals from frontal cortex to sensory cortex contribute to target-distractor selectivity. Overall\, these studies reveal cortical and subcortical mechanisms by which sensory signals are appropriately routed according to goal direction (Zagha 2020).
URL:https://brain.uci.edu/event/cncm-seminar-dr-edward-zagha/
LOCATION:Virtual Event
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/image-1.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220305T090000
DTEND;TZID=America/Los_Angeles:20220305T160000
DTSTAMP:20260421T133738
CREATED:20220126T234650Z
LAST-MODIFIED:20220126T234650Z
UID:10000294-1646470800-1646496000@brain.uci.edu
SUMMARY:2022 Irvine Brain Bee
DESCRIPTION:Join us for a day of neuroscience fun at UC Irvine! Laboratory tours\, hands-on brain activities\, keynote lecture and an opportunity to meet neuroscientists. The competition is a small portion of the day and we invite all high schoolers to participate regardless of how much you know about the brain!
URL:https://brain.uci.edu/event/2022-irvine-brain-bee/
LOCATION:Qureshey Research Laboratory\, 506 C Student Center\, Irvine\, CA 92697\, Qureshey Research Laboratory\, 506 C Student Center\, Irvine\, CA 92697-3800\, Irvine\, CA\, 92697-3800\, United States
CATEGORIES:Community,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/brainbeelogo_final.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220310T120000
DTEND;TZID=America/Los_Angeles:20220310T130000
DTSTAMP:20260421T133738
CREATED:20220214T180159Z
LAST-MODIFIED:20220224T165437Z
UID:10000299-1646913600-1646917200@brain.uci.edu
SUMMARY:Anatomy & Neurobiology Seminar with Jill K Leutgeb\, PhD
DESCRIPTION:Hippocampal Network Computations for Memories and Decisions \nJoin the Department of Anatomy & Neurobiology for a virtual seminar featuring Jill K Leutgeb\, PhD\, Walter F. Heiligenberg Professor of Neuroethology and Professor of Neurobiology in the Division of Biological Sciences at UC San Diego.
URL:https://brain.uci.edu/event/anatomy-neurobiology-seminar-with-jill-k-leutgeb-phd/
LOCATION:Virtual Event
CATEGORIES:All,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/jleutgeb_3-e1644861807857.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220322T160000
DTEND;TZID=America/Los_Angeles:20220322T170000
DTSTAMP:20260421T133738
CREATED:20220222T165852Z
LAST-MODIFIED:20220316T194804Z
UID:10000302-1647964800-1647968400@brain.uci.edu
SUMMARY:Jun Nagai\, PhD
DESCRIPTION:EpiCenter 2021-2022 Seminar Series \nJoin the UCI Department of Anatomy and Neurobiology in their EpiCenter Seminar Series featuring Jun Nagai\, PhD\, Team Leader of the Glia-Neuron Circuit Dynamics Lab at the RIKEN Center for Brain Science.
URL:https://brain.uci.edu/event/jun-nagai-phd/
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/image-2.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220323T090000
DTEND;TZID=America/Los_Angeles:20220323T150000
DTSTAMP:20260421T133738
CREATED:20220208T183410Z
LAST-MODIFIED:20220222T200859Z
UID:10000297-1648026000-1648047600@brain.uci.edu
SUMMARY:Conte Center@UCI 9th Annual Symposium\, featuring Keynote Speaker\, Dr. Diego Pizzagalli
DESCRIPTION:Join the UCI Conte Center at its 9th Annual Symposium titled\, Origins of Mental Health and Disease: Research and Reality\, happening on March 23\, 2022. The event features keynote speaker\, Diego Pizzagalli\, Ph.D.\, Professor of Psychiatry at Harvard Medical School\, and the Center Director for a Silvio O. Conte Center for Basic Translational Mental Health Research focused on the neurobiology of and novel treatment targets for depression and anxiety disorders. \nView the event flyer here. \n 
URL:https://brain.uci.edu/event/conte-center-9th-annual-symposium/
LOCATION:Beckman Center of the National Academies of Sciences & Engineering\, 100 Academy Wy\, Irvine\, CA\, 92617\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/image.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220405T100000
DTEND;TZID=America/Los_Angeles:20220405T110000
DTSTAMP:20260421T133738
CREATED:20220322T160036Z
LAST-MODIFIED:20220322T162146Z
UID:10000310-1649152800-1649156400@brain.uci.edu
SUMMARY:UCI CNCM Seminar: Jianhua Cang\, PhD
DESCRIPTION:Visual Processing in the Mouse Superior Colliculus \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Jianhua Cang of the University of Virginia. \nAbstract: \n\n\nThe superior colliculus (SC)\, or optic tectum\, is an evolutionarily conserved structure that receives direct retinal input in all vertebrates. It was the most sophisticated visual center until the neocortex evolved in mammals. In mice\, a mammalian species that has become a useful model in vision research\, 85–90% of retinal ganglion cells project to the SC\, making it the most prominent visual structure in this species. In the past several years\, we have performed a series of functional studies of the mouse SC\, especially the aspect of motion processing. In these studies\, we have (1) revealed diverse visual response properties in the mouse SC (Wang\, Sarnaik et al.\, J. Neuroscience\, 2010; Zhao\, Liu and Cang\, Neuron\, 2014; Savier et al.\, 2019; Chen et al.\, 2021); (2) discovered a highly specialized lamina in the most superficial SC for movement direction (Inayat\, Barchini et al.\, J. Neuroscience\, 2015); (3) demonstrated a retinal origin ofSC direction selectivity (Shi\, Barchini et al.\, Nature Neuroscience\, 2017); and (4) studied how SC neurons encode motion contrast (Barchini et al.\, 2018). In this presentation\, I will briefly review these published findings and describe our recent efforts in linking visual response properties to genetically identified cell types in the SC. \nFor those registering for in-person there is a 22 max capacity.\nIn-Person Location:\nInterdisciplinary Science and Engineering Building (ISEB)\nS. Circle View Dr\, Irvine\nConference Room 5020
URL:https://brain.uci.edu/event/uci-cncm-seminar-jianhua-cang-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) 1200\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/03/image.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20220405T110000
DTEND;TZID=UTC:20220405T120000
DTSTAMP:20260421T133738
CREATED:20210810T003204Z
LAST-MODIFIED:20220322T163421Z
UID:10000259-1649156400-1649160000@brain.uci.edu
SUMMARY:CNLM Colloquium with Tirin Moore\, Ph.D.
DESCRIPTION:Shared Neural Circuitry of Visuomotor Integration and Visual Cognition \nThe CNLM will be hosting Dr. Tirin Moore\, Professor of Neurobiology at Stanford University\, in a colloquium where he will present his latest research. \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n 
URL:https://brain.uci.edu/event/cnlm-colloquium-with-tirin-moore-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-5.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220411T110000
DTEND;TZID=America/Los_Angeles:20220411T120000
DTSTAMP:20260421T133738
CREATED:20220407T151154Z
LAST-MODIFIED:20220407T151507Z
UID:10000314-1649674800-1649678400@brain.uci.edu
SUMMARY:Neurobiology and Behavior Seminar: Dr. Eitan Schechtman
DESCRIPTION:Biasing memory processing during sleep to enhance cognition and improve wellbeing \nJoin the UCI Department of Neurobiology and Behavior in a hybrid seminar featuring Dr. Eitan Schechtman of the Cognitive Neuroscience Lab at Northwestern University. \nHybrid Event\nThe seminar will be live-streamed via zoom and in person.\nPlease RSVP to receive zoom link. \nIn-Person Meeting: Dale Melbourne Herklotz Conference Room\,\nthe Center for the Neurobiology of Learning and Memory 300 Qureshey Research Lab \n \nAbstract: Sleep is critical for the stabilization of memories. This process is thought to be supported by the reactivation of memories\, thereby strengthening the neural infrastructure supporting them. Theoretical accounts of this consolidation process focus on the process through which memories are independently strengthened\, but in natural settings\, individual memories never exist in a vacuum. In this talk\, I will present a series of studies exploring the extent of memory reactivation during sleep in humans\, how interactions between memories impact the consolidation process and the role of encoding context in memory processing during sleep. The main technique used to explore memory reactivation in these studies is targeted memory reactivation\, a behavioral manipulation that can selectively bias consolidation during sleep. The results demonstrate that multiple semantically related memories can be simultaneously consolidated during sleep. Additionally\, they show that memory reactivation during sleep may involve contextual reinstatement\, thereby impacting multiple contextually linked memories. These data suggest that reactivation during sleep is not limited to single memory items\, and can occur at the network or brain-state level. Relatedly\, we show that reactivating a suppression state during sleep can be used to selectively weaken memories. Taken together\, these results inform our current understanding regarding memory consolidation processes and open new avenues for translatable research to alleviate memory-related symptoms in patients suffering from psychiatric disorders.
URL:https://brain.uci.edu/event/neurobiology-and-behavior-seminar-dr-eitan-schechtman/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/image.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220412T120000
DTEND;TZID=America/Los_Angeles:20220412T130000
DTSTAMP:20260421T133738
CREATED:20220322T161224Z
LAST-MODIFIED:20220322T161317Z
UID:10000311-1649764800-1649768400@brain.uci.edu
SUMMARY:Wolfgang Löscher\, PhD
DESCRIPTION:EpiCenter 2021-2022 Seminar Series \nJoin the UCI Department of Anatomy and Neurobiology in their EpiCenter Seminar Series featuring Wolfgang Löscher\, PhD\, Professor\, Department of Pharmacology\, Toxicology and Pharmacy\, University of Veterinary Medicine Hannover.
URL:https://brain.uci.edu/event/wolfgang-loscher-phd/
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/03/image-1-e1647965587355.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220419T110000
DTEND;TZID=America/Los_Angeles:20220419T120000
DTSTAMP:20260421T133738
CREATED:20210826T235710Z
LAST-MODIFIED:20220301T003326Z
UID:10000263-1650366000-1650369600@brain.uci.edu
SUMMARY:Lara Rangel\, Ph.D.
DESCRIPTION:The CNLM will be hosting Dr. Lara Rangel\, Associate Professor of Cognitive Science at the University of California\, San Diego\, in a colloquium where she will present her latest research. \nThe flexible coordination of hippocampal spiking activity in rhythms \nDuring successful computation\, brain regions must have an efficient method for filtering information from multiple sources and coordinating communication with other regions. A great system for examining this is the hippocampus\, a brain structure critical for learning and memory that must integrate and associate various streams of information. Research conducted by Dr. Lara Maria Rangel suggests that successful processing of information in the hippocampus during an associative memory task is dependent on coordinated oscillatory activity\, and more specifically the flexible engagement of hippocampal cells in distinct rhythmic circuits. \nAbout Dr. Lara Rangel \nDr. Rangel is a systems neuroscientist\, whose work characterizes the temporal dynamics of cross-regional oscillatory interactions and the flexible participation of neurons in local rhythmic networks during behavior. \n \n  \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n 
URL:https://brain.uci.edu/event/lara-rangel-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-6.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20220503T110000
DTEND;TZID=UTC:20220503T120000
DTSTAMP:20260421T133738
CREATED:20210810T003441Z
LAST-MODIFIED:20220405T154906Z
UID:10000260-1651575600-1651579200@brain.uci.edu
SUMMARY:CNLM Colloquium with Duane Watson\, Ph.D.
DESCRIPTION:Understanding the link between language experience and language processing  \nThe CNLM will be hosting Duane Watson\, Ph.D.\, Professor of Psychology and Human Development at Vanderbilt University\, in a colloquium where he will present his latest research. \nAbstract: A speaker’s  language environment plays an important role in language use.  The language environment is critical for language learning and vocabulary growth in children\, and in predicting the difficulty of processing words and sentences in adults. In this talk I will present a set of studies that will show that the relationship between language exposure and language use is complex.  I will present experimental evidence suggesting that daily internet reading habits are linked to language processing skills.   On the other hand\, I will also present evidence showing that multiple exposures to complex sentences do not necessarily make these sentences easier to understand.  Finally\, I will discuss some of the ways in which the spoken language environment can play a role in language use\, and will present a pilot study showing that social factors\, such as a shared opinion with a conversational partner\, can influence subtle linguistic factors such as speech prosody. \n  \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n 
URL:https://brain.uci.edu/event/cnlm-colloquium-with-duane-watson-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-3.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220505T090000
DTEND;TZID=America/Los_Angeles:20220506T150000
DTSTAMP:20260421T133738
CREATED:20210824T213007Z
LAST-MODIFIED:20220314T172921Z
UID:10000262-1651741200-1651849200@brain.uci.edu
SUMMARY:2022 CNLM Spring Conference
DESCRIPTION:Since 1982\, the CNLM has hosted an annual scientific conference in the spring to discuss recent advances in the field and launch new collaborations and synergies. The conferences include several themed symposia\, short presentations by trainees\, panel discussions\, and keynote lectures. It is a crucial scientific development opportunity for students and postdocs as well as a faculty. Attendance is by invitation only (except for the triennial international conference – see 2018 below)\, and the program is developed by a committee of CNLM faculty fellows\, including external fellows. The conferences are highly renowned for their intellectual atmosphere\, use of the 50/50 discussion rule\, and the special edited volumes that result from them. Typical attendance at the annual conference is between 100-120 attendees. Attendance at the 2018 meeting exceeded 1\,000 scientists.  \nTo learn more about past conferences\, visit: https://cnlm.uci.edu/scientific-activities/spring-meeting/
URL:https://brain.uci.edu/event/2022-cnlm-spring-conference/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/SpringConferenceGraphics_FinalRevised-01.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220510T100000
DTEND;TZID=America/Los_Angeles:20220510T110000
DTSTAMP:20260421T133739
CREATED:20220420T212604Z
LAST-MODIFIED:20220420T212604Z
UID:10000317-1652176800-1652180400@brain.uci.edu
SUMMARY:Jonathan Ting\, PhD
DESCRIPTION:New opportunities for primate cellular neuroscience in the era of single cell genomics \nJoin the UCI Center for Neural Circuit Mapping for a hybrid seminar with Dr. Jonathan Ting from the Allen Institute for Brain Science. \nAbstract: \nHow many cell types exist in the brain and what are their unique functional properties?  Single cell transcriptomics provides a means to define discrete cell classes\, subclasses and types on the basis of gene expression signatures.  This approach has revolutionized neuroscience by providing foundational cell type taxonomies with unprecedented resolution and has led to the identification of previously unknown brain cell types.  In addition\, analytical tools enable precise alignment across diverse cell type taxonomies\, for example\, mapping of cell type homologies across species.  Such approaches will no doubt deepen our understanding of the evolution of brain cell types.  As a direct outcome of this progress\, a new challenge for the neuroscience field is to explore the unique cellular properties of these myriad brain cell types\, and to experimentally address whether transcriptomically distinct cell types serve functionally distinct roles in brain circuits.  Towards this aspirational goal\, how can we leverage the richness of single cell transcriptomics and epigenomics to target and manipulate this overwhelming diversity of brain cell types and across widely utilized mammalian model organisms?  In this talk I will describe the various projects and strategies my colleagues and I have developed at the Allen Institute to address these outstanding challenges\, with particular attention to creating new opportunities for primate cellular neuroscience.  I will focus on our published and unpublished biological discoveries coming from Patch-seq experiments exploring signature electrophysiological and morphological properties of transcripomically-identified primate neocortical cell types\, as well as the early implementation of first-in-class viral genetic tools for targeting brain cell types. \n  \nFor those registering for in-person there is a 22 max capacity. In addition\, to receiving your zoom virtual registration link\, you will receive a separate email reminder that you registered for the in-person.
URL:https://brain.uci.edu/event/jonathan-ting-phd/
LOCATION:Virtual Event
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/image-1.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220510T190000
DTEND;TZID=America/Los_Angeles:20220510T200000
DTSTAMP:20260421T133739
CREATED:20220509T192835Z
LAST-MODIFIED:20220509T192835Z
UID:10000322-1652209200-1652212800@brain.uci.edu
SUMMARY:Craig Walsh\, PhD
DESCRIPTION:The Impact of T Cells in Neurodegenerative Disease and Regenerative Therapies \nThis hybrid lecture will be held both in-person and online. If you would like to attend the lecture in person\, register here for the location details. \nCraig Walsh\, PhD\nDr. Walsh is a Professor of Molecular Biology and Biochemistry\, Co-Director of the Institute for Immunology\, Director of the Multiple Sclerosis Research Center and a Member of the Cancer Research Institute. \nHis research focuses on the role apoptotic signal transduction plays in the development\, activation and homeostasis of the immune system. Current interests include the study of death-receptors and the regulation of T cell activation.
URL:https://brain.uci.edu/event/craig-walsh-phd/
LOCATION:Virtual Event
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220512T100000
DTEND;TZID=America/Los_Angeles:20220512T110000
DTSTAMP:20260421T133739
CREATED:20220420T213355Z
LAST-MODIFIED:20220420T213355Z
UID:10000318-1652349600-1652353200@brain.uci.edu
SUMMARY:Thomas A. Blanpied\, PhD
DESCRIPTION:Dynamic control of synaptic nanostructure and function \nThe 2021 – 2022 Anatomy & Neurobiology Seminar Series presents\, Thomas A. Blanpied\, PhD\, Professor of Physiology from the University of Maryland School of Medicine\, in a virtual seminar where he will present his latest research. \n 
URL:https://brain.uci.edu/event/thomas-a-blanpied-phd/
CATEGORIES:Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/Blanpied_Thomas.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20220517T110000
DTEND;TZID=UTC:20220517T120000
DTSTAMP:20260421T133739
CREATED:20210810T003628Z
LAST-MODIFIED:20210928T155150Z
UID:10000261-1652785200-1652788800@brain.uci.edu
SUMMARY:CNLM Colloquium with Juliet Davidow\, Ph.D.
DESCRIPTION:Adolescent learning and goal-directed behavior \nThe CNLM will be hosting Juliet Davidow\, Ph.D.\,  Assistant Professor of Psychology at Northeastern University\, in a colloquium where she will present her latest research. \nAbstract:  \nAdolescence is a time of dynamic psychological and brain development. Previous research has shown that normative shifts in motivational processes during adolescence can relate to negative outcomes from risky actions\, driven by biased interactions among the brain’s striatocortical circuitry. However\, these brain systems support a range of functions\, including learning and goal-directed action selection. Could motivational and neurodevelopmental change during adolescence confer learning advantages? My work highlights how development of multiple learning and control systems in the brain contribute to different aspects of behavior\, associated with both benefits and costs in performance. Using fMRI and computational modeling approaches\, we revealed that adolescents can engage in better learning strategies compared to adults\, a behavioral profile that is supported by stronger interactions between the striatum and the hippocampus. However\, when contextual demands change\, stronger learning can become disadvantageous\, such as when previous learning interacts with inhibitory control – a set of processes supported by coordination among late-developing lateral and medial prefrontal cortical regions. Taken together\, we illustrate both the advantages and challenges that arise from emerging functional orchestration of the brain during adolescence. This work contributes to the characterization of this time of transition from childhood to adulthood. \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n\n 
URL:https://brain.uci.edu/event/cnlm-colloquium-with-juliet-davidow-ph-d/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-6.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220524T110000
DTEND;TZID=America/Los_Angeles:20220524T120000
DTSTAMP:20260421T133739
CREATED:20220523T191520Z
LAST-MODIFIED:20220523T191713Z
UID:10000325-1653390000-1653393600@brain.uci.edu
SUMMARY:Ted Abel\, PhD
DESCRIPTION:James L. McGaugh Distinguished Lecture \nMolecular Mechanisms of Long-Term Memory Storage \nPlease join the UCI Department of Neurobiology and Behavior in a hybrid event featuring Dr. Ted Abel of the Iowa Neuroscience Institute from the University of Iowa. \n \nAbstract: Research in the Abel lab at the University of Iowa focuses on the molecular mechanisms underlying the persistence of memory.  New experiences are initially encoded as labile short-term memories\, which are converted into stable long-term memory by gene transcription-dependent processes during memory consolidation.  In the hours after learning\, the induction of gene expression follows a specific pattern that involves transient waves of transcriptional activity\, which are needed for memory consolidation. This transcriptional regulation is meditated by epigenomic mechanisms such as histone acetylation. These epigenetic modifications are critical for the long-lasting regulation of gene expression during development and may be a major mechanism of information storage in the brain. Changes in these epigenetic modifications contribute to impairments in synaptic plasticity and cognitive function associated with many neurodevelopmental and neuropsychiatric disorders. Histone acetylation in an important epigenetic mark\, and we have shown that the metabolic enzyme acetyl-CoA synthetase 2 (ACSS2) directly regulates histone acetylation important for long-term spatial memory. ACSS2 is present in the nucleus where it generates acetyl co-A ‘on-site’ at chromatin for histone acetylation and the transcription of key neuronal genes. A critical question has been to identify the genes targeted by these epigenetic regulatory processes. The NR4A “orphan” nuclear receptors are important targets of epigenetic mechanisms mediating memory storage\, and they act as molecular switches for long-term memory storage. In our recent work\, we have shown we have found that NR4A proteins regulate the transcription of genes encoding chaperones that localize to the endoplasmic reticulum (ER). These chaperones function to traffic plasticity-related proteins to the cell surface during long lasting forms of synaptic plasticity and memory. Our understanding of the transcriptional cascades that mediate the consolidation and storage of long- term memory may ultimately lead to the development of new treatments for the debilitating cognitive deficits associated with neuropsychiatric\, neurodevelopmental\, and neurodegenerative disorders.
URL:https://brain.uci.edu/event/ted-abel-phd/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:All,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-3-scaled-e1653333376368.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220525T150000
DTEND;TZID=America/Los_Angeles:20220525T170000
DTSTAMP:20260421T133739
CREATED:20220207T185913Z
LAST-MODIFIED:20220216T000055Z
UID:10000296-1653490800-1653498000@brain.uci.edu
SUMMARY:2022 CNLM Awards Ceremony
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for the 2021 CNLM Awards Ceremony The CNLM offers awards to exceptional postdoctoral researchers\, graduate trainees\, undergraduates students\, and faculty.  Awardees will be presented with a plaque and $1\,000 stipend and will be invited to present their work in brief Elevator Pitch format to the UCI academic community and the public at our annual CNLM Awards Ceremony. \n  \nApplications for the 2021 CNLM Awards are due in February. Stay tuned! \nFor more information\, please visit: https://cnlm.uci.edu/awards/ \n 
URL:https://brain.uci.edu/event/2022-cnlm-awards-ceremony/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/cnlm-awards-slide-2022-01.png
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220607T110000
DTEND;TZID=America/Los_Angeles:20220607T120000
DTSTAMP:20260421T133739
CREATED:20220517T152320Z
LAST-MODIFIED:20220517T152320Z
UID:10000324-1654599600-1654603200@brain.uci.edu
SUMMARY:James L. McGaugh Distinguished Lecture: Kay Tye\, PhD
DESCRIPTION:Neural Representations of Social Homeostasis \nJoin the UCI Department of Neurobiology and Behavior for a virtual seminar featuring\, Dr. Kay Tye of the Salk Institute. \nAbstract: \nHow does our brain rapidly determine if something is good or bad? How do we know our place within a social group? How do we know how to behave appropriately in dynamic environments with ever-changing conditions?\nThe Tye Lab is interested in understanding how neural circuits important for driving positive and negative motivational valence (seeking pleasure or avoiding punishment) are anatomically\, genetically and functionally arranged.  We study the neural mechanisms that underlie a wide range of behaviors ranging from learned to innate\, including social\, feeding\, reward-seeking and anxiety-related behaviors. We have also become interested in “social homeostasis” — how our brains establish a preferred set-point for social contact\, and how this maintains stability within a social group.  How are these circuits interconnected with one another\, and how are competing mechanisms orchestrated on a neural population level? We employ optogenetic\, electrophysiological\, electrochemical\, pharmacological and imaging approaches to probe these circuits during behavior.
URL:https://brain.uci.edu/event/james-l-mcgaugh-distinguished-lecture-kay-tye-phd/
LOCATION:Virtual Event
CATEGORIES:Faculty,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-2.jpeg
END:VEVENT
END:VCALENDAR