BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Brain - ECPv6.15.18//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Brain
X-ORIGINAL-URL:https://brain.uci.edu
X-WR-CALDESC:Events for Brain
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/Los_Angeles
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20220313T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20221106T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20230312T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20231105T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20240310T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20241103T090000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20250309T100000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0700
TZOFFSETTO:-0800
TZNAME:PST
DTSTART:20251102T090000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240312T100000
DTEND;TZID=America/Los_Angeles:20240312T110000
DTSTAMP:20260419T081558
CREATED:20240125T233026Z
LAST-MODIFIED:20240125T234220Z
UID:10000467-1710237600-1710241200@brain.uci.edu
SUMMARY:Keri Martinowich\, PhD
DESCRIPTION:Associate Professor\, Department of Psychiatry and Behavioral Sciences Keri Martinowich\, PhD from Johns Hopkins University Presents: \n“Cell type and spatially-resolved multiomic approaches for understanding human brain disorders” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/keri-martinowich-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-11.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240305T110000
DTEND;TZID=America/Los_Angeles:20240305T120000
DTSTAMP:20260419T081558
CREATED:20231009T215006Z
LAST-MODIFIED:20240229T212335Z
UID:10000432-1709636400-1709640000@brain.uci.edu
SUMMARY:J. David Jentsch\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. J. David Jentsch\, Distinguished Professor and Chair of psychology at Binghamton University. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nDiversity to the rescue: Identifying novel molecular regulators of addiction liability
URL:https://brain.uci.edu/event/j-david-jentsch-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/jjentsch-2.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240227T160000
DTEND;TZID=America/Los_Angeles:20240227T170000
DTSTAMP:20260419T081558
CREATED:20240125T215546Z
LAST-MODIFIED:20240125T233826Z
UID:10000466-1709049600-1709053200@brain.uci.edu
SUMMARY:Seth Pollak\, PhD
DESCRIPTION:Join Seth Pollak\, PhD for his talk at the UCI Conte Center Seminar Series \n“Re-thinking Adversity: Early Life Stress from the Child’s Perspective” by Seth Pollak\, PhD\, Vaughan-Bascom Distinguished Professor\, Department of Psychology\, Pediatrics\, Anthropology; LaFollette School of Public Affairs\, University of Wisconsin – Madison
URL:https://brain.uci.edu/event/uci-conte-center-seminar-series-with-seth-pollak-phd/
LOCATION:Plumwood/Showa Denko Lecture Hall
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-9.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240227T100000
DTEND;TZID=America/Los_Angeles:20240227T110000
DTSTAMP:20260419T081558
CREATED:20240125T201508Z
LAST-MODIFIED:20240125T234503Z
UID:10000464-1709028000-1709031600@brain.uci.edu
SUMMARY:Yimin Zou\, PhD
DESCRIPTION:Professor in the Department of Neurobiology of UCSD Yimin Zou\, PhD presents: \n“Planar cell polarity proteins in glutamatergic synapse formation and maintenance” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/yimin-zou-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-14.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240223T110000
DTEND;TZID=America/Los_Angeles:20240223T120000
DTSTAMP:20260419T081558
CREATED:20240129T160947Z
LAST-MODIFIED:20240129T161317Z
UID:10000471-1708686000-1708689600@brain.uci.edu
SUMMARY:Frances Wiseman\, PhD
DESCRIPTION:The CFAR-DS Research Seminar Series hosts scientists from UC Irvine and beyond who conduct research focused on Down syndrome\, including research ranging from human participants to animal models. This seminar series is intended for scientists\, although all are welcome to attend. \nOn Friday\, February 23\, 2024 at 11:00 am Pacific Time please join us via Zoom for a presentation by Frances Wiseman\, PhD titled “Understanding differences in Down syndrome – Alzheimer’s disease: a focus on amyloid-β formation and response.” \nFrances Wiseman\, PhD is Programme Leader for Animal Models at the UK Dementia Research Institute. Dr Wiseman will discuss her group’s recent research using combinations of Down syndrome and amyloid-β accumulation mouse models; to understand how additional copies of chromosome 21 genes other than APP may modulate Alzheimer’s disease development in people who have Down syndrome. This will include a discussion of Mumford et al 2022\, PMID: 35835549 and recent follow-up unpublished data examining the interferon amyloid-β response in a new mouse model of Down syndrome-Alzheimer’s disease.
URL:https://brain.uci.edu/event/uci-center-for-aging-research-in-down-syndrome-seminar/
LOCATION:Zoom\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/CFAR_DS-_Seminar_Wiseman_Feb2024_.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240220T100000
DTEND;TZID=America/Los_Angeles:20240220T110000
DTSTAMP:20260419T081558
CREATED:20240125T191348Z
LAST-MODIFIED:20240125T235133Z
UID:10000463-1708423200-1708426800@brain.uci.edu
SUMMARY:Michelle Jones-London\, PhD
DESCRIPTION:Chief of Office of Programs to Enhance Neuroscience Workforce Diversity Michelle Jones-London\, PhD from NIH/NINDS presents: \n“An OPEN Conversation: NINDS Strategies for Enhancing the Diversity of Neuroscience Researchers” \nHybrid: ISEB 1200 & Zoom \n 
URL:https://brain.uci.edu/event/michelle-jones-london-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-12.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240215T110000
DTEND;TZID=America/Los_Angeles:20240215T120000
DTSTAMP:20260419T081558
CREATED:20240202T182333Z
LAST-MODIFIED:20240202T182333Z
UID:10000477-1707994800-1707998400@brain.uci.edu
SUMMARY:Garret Anderson\, PhD
DESCRIPTION:The department of Anatomy & Neurobiology will host guest speaker Garret Anderson from UC Riverside\, who will give a talk on ““Latrophilin cell-type specific expression and implications for neural circuit development”
URL:https://brain.uci.edu/event/garret-anderson-phd/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/02/Capture.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240215T100000
DTEND;TZID=America/Los_Angeles:20240215T110000
DTSTAMP:20260419T081558
CREATED:20240125T184404Z
LAST-MODIFIED:20240125T234347Z
UID:10000462-1707991200-1707994800@brain.uci.edu
SUMMARY:Sandeep Robert Datta\, MD\, PhD
DESCRIPTION:Professor of Neurobiology Sandeep Robert Datta\, MD\, PhD from Harvard Medical School presents: \n“Using Machine Learning to Discover How the Brain Builds Behavior” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/sandeep-robert-datta-md-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-13.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240213T110000
DTEND;TZID=America/Los_Angeles:20240213T120000
DTSTAMP:20260419T081558
CREATED:20240124T220420Z
LAST-MODIFIED:20240125T233901Z
UID:10000459-1707822000-1707825600@brain.uci.edu
SUMMARY:Katalin Gothard\, Ph.D.
DESCRIPTION:Join Dr. Katalin Gothard in the James L. McGaugh Distinguished Seminar Series In-Person or over Zoom! \n“A context-dependent switch from sensing to feeling in the primate amygdala”\n\nKatalin M. Gothard\, M.D.\, Ph.D.\nProfessor of Physiology\, Neurology\, and Neuroscience The University of Arizona College of Medicine Department of Physiology \nAbstract: \nTactile signals elicited in the periphery by social and affective touch acquire emotional significance in the brain. As the amygdala processes the valence of all sensory stimuli\, we predicted that the positive valence of grooming would strongly activate the monkey amygdala. To test this hypothesis\, we compared neural activity in the amygdala and the primary somatosensory cortex in response to social grooming and gentle airflow delivered to the same areas of the skin. Neurons in the somatosensory cortex responded to both types of tactile stimuli. In the amygdala\, however\, neurons did not respond to individual grooming sweeps even though grooming elicited autonomic states indicative of positive affect. Instead of responses to individual touch stimuli\, a large proportion of neurons showed enhanced or suppressed baseline firing rates that persisted throughout a grooming bout. These changes were attributed to social context because the presence of the groomer alone could account for increases or decreases in baseline firing rates. It appears\, therefore\, that during grooming\, the amygdala stops responding to external inputs on a short time scale but remains responsive to social context\, and the associated affective states\, on longer time scales.
URL:https://brain.uci.edu/event/james-l-mcgaugh-distinguished-seminar-series/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-6.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240206T110000
DTEND;TZID=America/Los_Angeles:20240206T120000
DTSTAMP:20260419T081558
CREATED:20231009T213853Z
LAST-MODIFIED:20231205T181600Z
UID:10000431-1707217200-1707220800@brain.uci.edu
SUMMARY:Elizabeth A. Buffalo\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Elizabeth A. Buffalo\, professor and chair of physiology and biophysics at the University of Washington. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nNeural Dynamics of Memory Formation in the Primate Hippocampus  \n \nDescription:  \nOur understanding of the hippocampus has been framed by two landmark discoveries: the discovery by Scoville and Millner that hippocampal damage causes profound and persistent amnesia and the discovery by O’Keefe and Dostrovsky of hippocampal place cells in rodents. However\, it has been unclear to what extent spatial representations are present in the primate brain and how to reconcile these representations with the known mnemonic function of this region. I will discuss a series of experiments that have examined neural activity in the hippocampus in monkeys performing behavioral tasks including foraging and spatial memory tasks in a virtual environment. These data demonstrate that behavioral task structure has a significant influence on hippocampal activity\, with neurons responding to all salient events within the task. Taken together\, these data are consistent with the idea that activity in the hippocampus tracks ongoing experience in support of memory formation.
URL:https://brain.uci.edu/event/elizabeth-buffalo-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/beth-buffalo-250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240125T080000
DTEND;TZID=America/Los_Angeles:20240125T170000
DTSTAMP:20260419T081558
CREATED:20240125T235339Z
LAST-MODIFIED:20240125T235339Z
UID:10000470-1706169600-1706202000@brain.uci.edu
SUMMARY:Weizhe Hong\, PhD
DESCRIPTION:Professor of Biological Chemistry & Neurobiology Weizhe Hong\, PhD from the University of California\, Los Angeles Presents: \n“TBD” \nHybrid: ISEB 1200 & Zoom \n 
URL:https://brain.uci.edu/event/weizhe-hong-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-16.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240116T160000
DTEND;TZID=America/Los_Angeles:20240116T170000
DTSTAMP:20260419T081558
CREATED:20231207T161611Z
LAST-MODIFIED:20231207T162001Z
UID:10000453-1705420800-1705424400@brain.uci.edu
SUMMARY:UCI Conte Center Seminar Series with Pat Levitt\, PhD
DESCRIPTION:“Functional Implications of Developmental Heterogeneity” by Pat Levitt\, PhD\, Chief Scientific Officer\, Senior Vice President and Director\, The Saban Research Institute\, Simms/Mann Chair in Developmental Neurogenetics\, Children’s Hospital Los Angeles\, WM Keck Provost Professor of Neurogenetics\, Keck School of Medicine of USC
URL:https://brain.uci.edu/event/uci-conte-center-seminar-series-with-pat-levitt-phd/
LOCATION:Plumwood/Showa Denko Lecture Hall
CATEGORIES:All
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/12/UCI-Conte-Center-Seminar-Series-with-Pat-Levitt-PhD.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240116T100000
DTEND;TZID=America/Los_Angeles:20240116T110000
DTSTAMP:20260419T081558
CREATED:20240125T183718Z
LAST-MODIFIED:20240125T183828Z
UID:10000461-1705399200-1705402800@brain.uci.edu
SUMMARY:Donghui Zhu\, PhD
DESCRIPTION:SUNY Empire Innovation Professor Donghui Zhu\, PhD from Stony Brook University Presents: \n“Amyloid beta glycation leads to neuronal mitochondrial dysfunction and Alzheimer’s pathogenesis via VDAC1-dependent mtDNA efflux” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/donghui-zhu-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/donghui_zhu2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231128T110000
DTEND;TZID=America/Los_Angeles:20231128T120000
DTSTAMP:20260419T081558
CREATED:20231009T211005Z
LAST-MODIFIED:20231009T214419Z
UID:10000429-1701169200-1701172800@brain.uci.edu
SUMMARY:Anna K. Gillespie\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nSteps toward exploring the therapeutic potential of hippocampal replay \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Anna Gillespie\, assistant professor of biological structure\, lab medicine\, and pathology at University of Washington. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nExecuting memory-guided behavior requires storage of information about experience and later recall of that information to inform choices. Hippocampal sharp-wave ripple (SWR) events are associated with the time-compressed “replay” of representations of past experience\, and multiple correlative and causal studies have demonstrated that SWRs critically contribute to these cognitive functions. Consistent with its role in memory processes\, changes in SWRs have been reported concurrent with memory impairment in several rodent models of Alzheimer’s disease. Rescuing replay in Alzheimer’s could thus improve memory symptoms; however\, our current options for promoting physiologically relevant replay are quite limited. To address this gap\, we developed a neurofeedback paradigm for rats in which the real-time detection of SWRs triggers the delivery of positive reinforcement (food reward). In young adult animals\, this training protocol increased the prevalence of task-relevant replay during the targeted neurofeedback period by changing the temporal dynamics of SWR occurrence\, and was also associated with neural and behavioral forms of compensation after the targeted period. This work demonstrates that subjects can learn to use neurofeedback to modulate physiologically relevant patterns of hippocampal network activity and lays the foundation for future work in subjects with compromised replay\, such as rodent models of Alzheimer’s disease.
URL:https://brain.uci.edu/event/anna-k-gillespie-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/anna-gillespie-250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231109T160000
DTEND;TZID=America/Los_Angeles:20231109T170000
DTSTAMP:20260419T081558
CREATED:20231027T200250Z
LAST-MODIFIED:20231027T201325Z
UID:10000445-1699545600-1699549200@brain.uci.edu
SUMMARY:Flavio Donato\, Ph.D.
DESCRIPTION:Conte Center @ UCI Seminar Series \nMemory dynamics through the divergent recruitment of developmentally-defined hippocampal traces \nJoin the Conte Center @ UCI for a seminar by Dr. Flavio Donato\, assistant professor of neurobiology at the University of Basel.
URL:https://brain.uci.edu/event/flavio-donato-ph-d/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/falvio-donato.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231108T120000
DTEND;TZID=America/Los_Angeles:20231108T130000
DTSTAMP:20260419T081558
CREATED:20231103T152254Z
LAST-MODIFIED:20231103T152452Z
UID:10000447-1699444800-1699448400@brain.uci.edu
SUMMARY:Aniruddh Patel\, Ph.D.
DESCRIPTION:From the Department of Psychology at Tufts University\, Aniruddh Patel\, Ph.D. will be presenting “The Biology of the Beat: Motor Contributions to Auditory Cognitive Processing” at The Department of Cognitive Sciences’ Colloquia Series.
URL:https://brain.uci.edu/event/thethe-department-of-cognitive-sciences-colloquia-series-presents-aniruddh-patel-ph-d-the-biology-of-the-beat-motor-contributions-to-auditory-cognitive-processing/
LOCATION:Virtual via Zoom\, CA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231025T120000
DTEND;TZID=America/Los_Angeles:20231025T130000
DTSTAMP:20260419T081558
CREATED:20231019T202107Z
LAST-MODIFIED:20231019T202107Z
UID:10000443-1698235200-1698238800@brain.uci.edu
SUMMARY:Effects of Narrative Structure and Agency on Memory
DESCRIPTION:The Department of Cognitive Sciences’\nColloquia Series presents: \nJanice Chen\, Ph.D.\nAssistant Professor\, Department of\nPsychological & Brain Sciences\nJohns Hopkins University \n  \nEffects of narrative structure and agency on memory \nThe world confronts our senses with a continuous stream of rapidly changing information. Yet\, we experience life as a series of episodes or events\, and in memory these pieces seem to become even further organized. How do we recall an give structure to this complex information? Recent studies have begun to examine these questions using naturalistic stimuli and behavior: subjects view audiovisual movies or read interactive stories\, then freely recount their memories of the events. Within the default network\, we find distinct brain activity patterns corresponding to individual events\, which reappear during verbal recollection; memories and neural patterns are influenced by the network structure of links between events in the narrative\, and these effects are modulated by agency. These observations construct a picture of how the brain supports our ability to comprehend and recall real-world events as they unfold continuously across time.
URL:https://brain.uci.edu/event/effects-of-narrative-structure-and-agency-on-memory/
LOCATION:Virtual via Zoom\, CA
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/Untitled-design-1-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231024T110000
DTEND;TZID=America/Los_Angeles:20231024T120000
DTSTAMP:20260419T081558
CREATED:20230928T212745Z
LAST-MODIFIED:20231012T030909Z
UID:10000424-1698145200-1698148800@brain.uci.edu
SUMMARY:Roger Nicoll\, M.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) and the Department of Anatomy and Neurobiology for a hybrid event featuring Dr. Roger Nicoll\, professor of cellular and molecular pharmacology at the University of California\, San Francisco. \nThe Biochemistry of Memory: A (not so) New and Specific Hypothesis \nEvent is jointly sponsored through the CNLM Colloquium Series and the Anatomy and Neurobiology Seminar Series. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \n\nCaMKII and long-term potentiation (LTP) were discovered within a decade of each other and have been inextricably intertwined ever since. In 1984 Francis Crick proposed that a memory molecule should possess two properties. First\, it should be a multimeric protein with identical subunits that can phosphorylate one another. Second\, to address how memories outlast molecular turnover he proposed that naïve unphosphorylated subunits could exchange into the phosphorylated multimer and become phosphorylated. Within two years biochemical studies established that CaMKII satisfied the first prediction. Recent biochemical studies have shown that unphosphorylated CaMKII subunits can exchange into phosphorylated CaMKII multimers\, thus satisfying Crick’s second prediction. My talk will focus on linking the biochemical properties of CaMKII to LTP. I will show that the autophosphorylation of CaMKII maintains LTP (memory) by establishing a stable CaMKII/NMDA receptor complex\, resulting in the synaptic capture of AMPA receptors. LTP survives the protein turnover of CaMKII\, which is complete within 2 weeks\, by its phosphorylation of newly synthesized naïve CaMKII molecules.
URL:https://brain.uci.edu/event/roger-nicoll-m-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/Roger-Nicoll-464x464-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231020T150000
DTEND;TZID=America/Los_Angeles:20231020T160000
DTSTAMP:20260419T081558
CREATED:20231012T220819Z
LAST-MODIFIED:20231012T221033Z
UID:10000441-1697814000-1697817600@brain.uci.edu
SUMMARY:Samuel Barnes Science Discussion UCI Conte Center
DESCRIPTION:Join Samuel Barnes\, PhD for his discussion on “Mechanisms underlying flexible reward learning deficits in rodents” virtually with the UCI Conte Center. \nZoom Link \nPasscode: 764583
URL:https://brain.uci.edu/event/samuel-barnes-science-discussion-uci-conte-center/
LOCATION:Virtual via Zoom\, CA
CATEGORIES:All,Scientific
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/unnamed.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231020T080000
DTEND;TZID=America/Los_Angeles:20231020T120000
DTSTAMP:20260419T081558
CREATED:20230813T233250Z
LAST-MODIFIED:20230929T190556Z
UID:10000418-1697788800-1697803200@brain.uci.edu
SUMMARY:Conspiracy Thinking in American Politics
DESCRIPTION:This Symposium will include the Annual Jerrold Post Lecture on Neuropolitics\, given by Keynote Speaker George Marcus. Psychiatrist Jerrold Post\, MD (1934-2020)\, who was Professor of Political Science at George Washington University\, was a founder of the field of political psychology and author of many influential books on the psychology of political leadership.
URL:https://brain.uci.edu/event/conspiracy-thinking-in-american-politics/
LOCATION:Virtual via Zoom\, CA
CATEGORIES:All
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/08/2023-Neuropolitics-Symposium-Header-v2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231017T110000
DTEND;TZID=America/Los_Angeles:20231017T120000
DTSTAMP:20260419T081558
CREATED:20230929T190105Z
LAST-MODIFIED:20231009T214316Z
UID:10000426-1697540400-1697544000@brain.uci.edu
SUMMARY:Mayank Mehta\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nHippocampus 2.0: Three simple rules \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Mayank Mehta\, professor of physics\, astronomy\, neurology\, and neurobiology at UCLA. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nThe hippocampus is implicated in many learning and memory disorders including Alzheimer’s. Dozens of drugs have cured these in mice but failed in humans. Hippocampal neurons in rodents show robust spatial selectivity. Hence\, the standard test of hippocampal function in mice is the Morris Water Maze\, an allocentric spatial memory task. However\, in freely behaving primates\, hippocampal neurons show very little spatial selectivity. Further\, hippocampal damage in humans causes profound non-spatial\, egocentric\, episodic memory deficits too\, whose neurophysiological analog in rodents is unclear. We propose a novel theory of hippocampal function\, Hippocampus 2.0\, which can reconcile these long-standing differences and provide several experimental tests of this theory. The results provide a unified framework for probing hippocampal function\, which could improve translation of therapies from mice to humans.
URL:https://brain.uci.edu/event/mayank-mehta-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/1516960566877.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231009T093000
DTEND;TZID=America/Los_Angeles:20231009T190000
DTSTAMP:20260419T081558
CREATED:20230804T180405Z
LAST-MODIFIED:20230804T181633Z
UID:10000416-1696843800-1696878000@brain.uci.edu
SUMMARY:AI & Biomedicine Symposium: AI and Neuroscience
DESCRIPTION:This year’s annual Southern California AI and Biomedicine Symposium will focus on AI and Neuroscience.  The event is co-sponsored by the UCI Institute for Genomics and Bioinformatics and the UCI Center for the Neurobiology of Learning and Memory. The free event includes a full day of talks\, lunch\, and reception. RSVP soon as space is limited. \nDownload Event Flyer
URL:https://brain.uci.edu/event/ai-biomedicine-symposium-ai-and-neuroscience/
LOCATION:Calit2 Auditorium\, 4100 Calit2 Building\, Irvine\, Irvine
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/08/ai-biomedical-symposium.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231006T080000
DTEND;TZID=America/Los_Angeles:20231006T180000
DTSTAMP:20260419T081558
CREATED:20230921T172807Z
LAST-MODIFIED:20230929T192644Z
UID:10000423-1696579200-1696615200@brain.uci.edu
SUMMARY:2023 Inaugural Symposium for the UCI Center for Neurotherapeutics
DESCRIPTION:Dr. Al La Spada\, Director\, and Dr. Rob Spitale\, Associate Director\, of the UCI Center for Neurotherapeutics are delighted to announce our upcoming Inaugural Symposium: “Exploring the Future of Neurotherapeutics” \nThe goals of the Inaugural Symposium are as follows: \n\nIntroduce the center to campus. Learn about the vision that drives us\, the milestones we’ve achieved\, and our ongoing goals to further develop the center on campus.\nAn update on state-of-the-art translational neuroscience research. Internationally renowned faculty will delineate ongoing efforts to understand the complexities of the human brain and develop innovative models and solutions for neurological diseases.Lecture topics will include therapeutic drug discovery and high-throughput methods to identify novel drug targets. Experts from diverse disciplines will explain how they are tackling the challenge of delivering small molecules and biological agents across the blood-brain barrier.\nSpurring interdisciplinary collaboration across campus. One of the core values at the UCI Center for Neurotherapeutics is collaboration\, especially between faculty in the physical sciences and the biological sciences.This unique occasion will be a forum to highlight opportunities for cross-disciplinary interactions and explore potential collaborations. By combining our expertise and diverse perspectives\, we can unlock new avenues of discovery and accelerate progress toward developing novel solutions for therapy development.\n\nOur exceptional line-up of guest speakers and UCI faculty speakers include: \n\nChristopher Austin (former Director of NCATS)\nMichael Lin (Stanford University)\nJulia Schaletzky (UC Berkeley)\nRandy Ashton (University of Wisconsin)\nAnne Bang (Sanford-Burnham-Prebys Medical Research Institute)\nViviana Gradinaru (California Institute of Technology)\nAlexandre Chan (UC Irvine)\nBrian Paegel (UC Irvine)\nSzu Wang (UC Irvine)\nErrol Arkilic (UC Irvine)\n\nWhether you are a student\, postdoctoral trainee\, faculty member\, or staff member\, we encourage you to join us\, so please mark your calendars!
URL:https://brain.uci.edu/event/2023-inaugural-symposium-for-the-uci-center-for-neurotheraputics/
LOCATION:Beckman Center of the National Academies of Sciences & Engineering\, 100 Academy Wy\, Irvine\, CA\, 92617\, United States
CATEGORIES:All
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/Symposium-Email-Header.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230919T160000
DTEND;TZID=America/Los_Angeles:20230919T170000
DTSTAMP:20260419T081558
CREATED:20230901T182647Z
LAST-MODIFIED:20230901T205440Z
UID:10000421-1695139200-1695142800@brain.uci.edu
SUMMARY:UCI Conte Center Seminar Series with Alexander Shackman\, PhD
DESCRIPTION:Please joint the Conte Center for a lecture from Alexander Shackman\, PhD\, Associate Professor\, Department of Psychology\, University of Maryland. \nDate: September 19\, 2023\, Time: 4:00 – 5:00PM (PT)\nTitle: The Nature and Neurobiology of Anxiety\nLocation: Plumwood House (Across From Medical Education) and also Telecast via Zoom\, passcode: 764583 \nPlease reach out to James Weinstock if you have any questions (jweinsto@uci.edu).
URL:https://brain.uci.edu/event/uci-conte-center-seminar-series-with-alexander-shackman-phd/
LOCATION:Plumwood/Showa Denko Lecture Hall
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/Untitled-design-3.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230909T150000
DTEND;TZID=America/Los_Angeles:20230909T180000
DTSTAMP:20260419T081558
CREATED:20230621T181326Z
LAST-MODIFIED:20230621T181326Z
UID:10000413-1694271600-1694282400@brain.uci.edu
SUMMARY:Down Syndrome Showcase
DESCRIPTION:A celebration of the creative and artistic talents of children and adults with Down Syndrome and an opportunity to learn about the factors that impact the health and well-being of people with Down Syndrome \nTalent Show and Art Exhibits: Anyone with Down syndrome who would like to perform on stage or display their art/crafts should contactcoordinator@dsaoc.org. Sign-ups are on a first-come\, first-served basis. \nPoster Presentations: Any UCI student or scholar interested in presenting their scientific findings related to Down syndrome should contact ndiprosp@uci.edu. \nAdmission and parking: Free. Every guest\, performer\, and exhibitor must have a ticket. Order through the theater box office: www.thebarclay.org. \nFor more information: Visit cfar-ds.uci.edu or e-mail: cfar-ds@uci.edu  \nLight refreshments will be served. 
URL:https://brain.uci.edu/event/down-syndrome-showcase/
LOCATION:Irvine Barclay Theater\, 4242 Campus Drive\, Irvine\, CA\, 92612\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/06/down-syndrome-showcase.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230825T080000
DTEND;TZID=America/Los_Angeles:20230825T151500
DTSTAMP:20260419T081558
CREATED:20230814T165820Z
LAST-MODIFIED:20230814T165820Z
UID:10000419-1692950400-1692976500@brain.uci.edu
SUMMARY:Register Today – Annual Alzheimer’s Disease Research Conference: Sex and Gender in Dementia Research and Care
DESCRIPTION:Did you know that women are at an increased risk of developing Alzheimer’s disease?\n\n\n\nAttend the Annual Southern California Alzheimer’s Disease Research Conference to learn more about this and other important topics related to sex and gender in dementia research and care.  The event is hosted by UCI MIND\, Alzheimer’s Orange County and the Alzheimer’s Association Orange County Chapter.\n\n\nAbout the Conference \n\nFriday\, August 25\, 2023\, 8:00 am – 3:15 pm PT\nHilton Irvine & Virtual\nCEUs can be added onto your registration for in-person attendees\n\n  \nWho should attend? \n\nFaculty\nResearchers\nStudents\nPeople living with dementia and their families\nHealthcare providers\nSenior and social service providers\nAnyone interested!\n\n\n\n\nClick here to visit our website to learn more about registration. \n  \nPlease note that CEUs are offered at a discounted rate this year. \n  \nTo register for this hybrid event\, click the button below.\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nRegister Now\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nFor questions\, please call Megan Witbracht at 949-824-9896.
URL:https://brain.uci.edu/event/register-today-annual-alzheimers-disease-research-conference-sex-and-gender-in-dementia-research-and-care/
LOCATION:Hilton Irvine and Virtual\, 18800 MacArthur Blvd\, Irvine\, CA\, 92612\, United States
CATEGORIES:All,Community,Scientific
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/08/Annual-Alzheimers-Disease-Research-Conference-Sex-and-Gender-in-Dementia-Research-and-Care.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230711T160000
DTEND;TZID=America/Los_Angeles:20230711T170000
DTSTAMP:20260419T081558
CREATED:20230630T170936Z
LAST-MODIFIED:20230630T171020Z
UID:10000414-1689091200-1689094800@brain.uci.edu
SUMMARY:Read Montague\, Ph.D.
DESCRIPTION:Reinforcement Learning\, Monoamines and the effort to connect neurochemical dynamics to Human Perception\n\nJoin the Conte Center @ UCI for their seminar series featuring Dr. Read Montague\, Virginia Tech Carilion Vernon Mountcastle Research Professor and director of the Center for Human Neuroscience Research at the Franlin Biomedical Research Institute.
URL:https://brain.uci.edu/event/read-montague-ph-d/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/06/read-montegue.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230630T110000
DTEND;TZID=America/Los_Angeles:20230630T120000
DTSTAMP:20260419T081558
CREATED:20230613T180620Z
LAST-MODIFIED:20230613T181255Z
UID:10000411-1688122800-1688126400@brain.uci.edu
SUMMARY:Hiruy Meharena\, PhD. - UCI Center for Aging Research in Down Syndrome (CFAR-DS) Seminar Series
DESCRIPTION:Please join us for the UCI Center for Aging Research in Down Syndrome (CFAR-DS) Seminar Series on Friday\, June 30 at 11 am Pacific Time \nHiruy Meharena\, PhD is an Assistant Professor in the Departments of Neurobiology and Molecular Biology in the School of Biological Sciences at UC San Diego. Hiruy’s group focuses on understanding how the brain develops at the molecular and cellular level to accomplish cognitive tasks. The overarching goal is to establish a comprehensive molecular map of the developing human brain in order to identify the cell-type specific gene-networks driving neurodevelopmental disorders associated with intellectual disability\, including Autism Spectrum Disorder and Down syndrome. Mouse models and human derived induced pluripotent stem cells (iPSCs) are utilized to decode the genomic and molecular signatures of intellectual disability during neurodevelopment and cognitive processing. \nPlease register here and you will be emailed the event details.
URL:https://brain.uci.edu/event/hiruy-meharena-phd-uci-center-for-aging-research-in-down-syndrome-cfar-ds-seminar-series/
LOCATION:Zoom\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/06/Hiruy-Meharena.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230601T110000
DTEND;TZID=America/Los_Angeles:20230601T120000
DTSTAMP:20260419T081558
CREATED:20230530T195435Z
LAST-MODIFIED:20230530T195453Z
UID:10000406-1685617200-1685620800@brain.uci.edu
SUMMARY:Natalie E. Zlebnik – ICAN Seminar Series
DESCRIPTION:ICAN Seminar Series\nThursday\, June 1\, 2023 at 11:00am\nThe seminar will be live streamed via Zoom and In-Person.\nZOOM LINK HERE \n \nNatalie E. Zlebnik\, PhD\nDivision of Biomedical Sciences\, University of California\, Riverside School of Medicine \n“Adolescent cannabinoid exposure: effects on dopamine system development and cocaine-motivated behavior”\nAbstract: Cannabis is the most commonly abused illicit drug among adolescents\, and excessive use in this population is associated with the development of psychiatric conditions\, including drug addiction. Adolescence is a critical period for the refinement and organization of neuronal connectivity\, especially within the mesocorticolimbic dopamine circuity. In particular\, dysregulation of the guidance cue receptor\, Dcc\, in ventral tegmental area (VTA) dopamine neurons disrupts spatiotemporal targeting of dopamine axons to the nucleus accumbens (NAc) and the medial prefrontal cortex (mPFC). We have previously demonstrated that exposure to amphetamine in early adolescence disrupts the development of dopamine circuitry development\, leading to alterations in cognitive processing and drug seeking in adulthood. Here\, we examine whether exposure to the synthetic cannabinoid 1 receptor (CB1R) agonist WIN-55\,212-2 (WIN) in early adolescence regulates Dcc mRNA expression in the VTA and induces alterations in drug-motivated behaviors and in dopamine function in adulthood. Preliminary findings demonstrate that adolescent exposure to WIN downregulates the Dcc receptor in the VTA and disrupts organization of mesocorticolimbic dopamine circuitry. Additionally\, WIN-treated mice display aberrant self-administration of cocaine in the absence of other behavioral impairments. Ongoing experiments will elucidate functional changes in cocaine-evoked phasic dopamine release in the NAc and mPFC. Overall\, these findings support that repeated exposure to a CB1R agonist in adolescence impacts mesocorticolimbic dopamine system maturation and may have important implications for dopamine-mediated learning and psychostimulant-motivated behavior later in life. \nBio: Natalie Zlebnik\, PhD\, is an Assistant Professor in the Division of Biomedical Sciences in the School of Medicine. She earned her doctorate in Neuroscience from the University of Minnesota\, and her postdoctoral fellowship was completed at the University of Maryland School of Medicine\, where her investigations focused on the role of the endocannabinoid system in normal reward-motivated behaviors and its therapeutic role in disorders of reward seeking. Her independent research program examines how drugs of abuse exploit neural mechanisms of motivated behavior to promote relapse and facilitate the transition to drug addiction. The goal is to identify molecular and circuit-level targets for the development of novel therapeutics to reduce drug craving and minimize the propensity to relapse.
URL:https://brain.uci.edu/event/natalie-e-zlebnik-ican-seminar-series/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:All
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/05/Natalie-E.-Zlebnik-–-ICAN-Seminar-Series.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230526T110000
DTEND;TZID=America/Los_Angeles:20230526T120000
DTSTAMP:20260419T081558
CREATED:20230420T165211Z
LAST-MODIFIED:20230420T165211Z
UID:10000399-1685098800-1685102400@brain.uci.edu
SUMMARY:UCI CFAR-DS Seminar Series - Dr. Beau Ances
DESCRIPTION:Please join us for the UCI Center for Aging Research in Down Syndrome (CFAR-DS) Seminar Series on May 26 at 11 am PT. We are thankful to have Dr. Beau Ances from Washington University in St. Louis visiting the University of California\, Irvine for this seminar. Over the past 15 years\, the Ances Bioimaging Laboratory (ABL) has focused on developing novel biomarkers for neurodegenerative diseases including HIV associated neurocognitive disorders (HAND)\, Alzheimer’s disease (AD)\, autoimmune encephalitis\, and Down syndrome. Dr. Ances will give a talk titled “Alzheimer Disease in Down Syndrome: One extra chromosome\, two extra hugs.” The presentation will be held in the Herklotz Conference Room but if you are not able to make it to the UCI campus\, you can attend through Zoom.
URL:https://brain.uci.edu/event/uci-cfar-ds-seminar-series-dr-beau-ances/
LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/04/CFAR_DS-_Seminar_Ances-_May-2023.png
END:VEVENT
END:VCALENDAR