BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Brain - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Brain X-ORIGINAL-URL:https://brain.uci.edu X-WR-CALDESC:Events for Brain REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/Los_Angeles BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20200308T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20201101T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20210314T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20211107T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20220313T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20221106T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20230312T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20231105T090000 END:STANDARD END:VTIMEZONE BEGIN:VTIMEZONE TZID:UTC BEGIN:STANDARD TZOFFSETFROM:+0000 TZOFFSETTO:+0000 TZNAME:UTC DTSTART:20200101T000000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20210921T110000 DTEND;TZID=America/Los_Angeles:20210921T120000 DTSTAMP:20260420T181343 CREATED:20210831T220649Z LAST-MODIFIED:20210831T220649Z UID:10000265-1632222000-1632225600@brain.uci.edu SUMMARY:CNCM Seminar: Hong Wei Dong\, PhD DESCRIPTION:Join the UCI Center for Neural Circuit Mapping in a seminar featuring Dr. Hong Wei Dong of UCLA. URL:https://brain.uci.edu/event/cncm-seminar-hong-wei-dong-phd/ LOCATION:CA CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-8.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20210923T120000 DTEND;TZID=America/Los_Angeles:20210923T130000 DTSTAMP:20260420T181343 CREATED:20210928T185802Z LAST-MODIFIED:20210928T185933Z UID:10000268-1632398400-1632402000@brain.uci.edu SUMMARY:LAMP Seminar - Dr. Andy Shih DESCRIPTION:Optical Dissection of Brain Capillary Function \nJoin the UCI Beckman Laser Institute & Medical Clinic for a virtual seminar featuring Dr. Andy Shih\, Assistant Professor at the Seattle Children’s Research Institute & University of Washington. \nAbstract \nMy laboratory uses in vivo multiphoton imaging and rodent models to shed light (quite literally) on regulation of cerebral blood flow. In particular\, we have focused recent attention on the vast capillary networks that distribute blood throughout the brain. We use light to both visualize capillary structure and flow\, as well as noninvasively manipulate neurovascular cells that control capillary flow. We specialize in the application and development of in vivo multi-photon imaging approaches to study brain microvascular structure and function in rodents. Our recent findings include the construction of capillary networks during early postnatal development\, regulation of blood flow in adulthood by capillary pericytes\, and capillary changes in gray and white matter that may contribute to metabolic insufficiencies during aging and dementia. I firmly believe that our efforts will provide a unique and physiologically relevant view of microvascular function\, dysfunction\, and repair\, and will yield strategies for protecting vascular function in diseases that degrade the brain’s microvasculature.  URL:https://brain.uci.edu/event/lamp-seminar-dr-andy-shih/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/09/image-1-e1632855563344.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20210928T110000 DTEND;TZID=UTC:20210928T120000 DTSTAMP:20260420T181343 CREATED:20210810T002522Z LAST-MODIFIED:20210820T214910Z UID:10000256-1632826800-1632830400@brain.uci.edu SUMMARY:CNLM Colloquium with Nii Addy\, Ph.D DESCRIPTION:The CNLM will be hosting Dr. Nii Addy\,Associate Professor  of Psychiatry at the Yale School of Medicine\, in a colloquium where he will present his latest research. \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n\n  URL:https://brain.uci.edu/event/cnlm-colloquium-with-nii-addy-ph-d/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-2-e1628530020745.jpeg ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211005T110000 DTEND;TZID=America/Los_Angeles:20211005T120000 DTSTAMP:20260420T181343 CREATED:20210929T165153Z LAST-MODIFIED:20210929T170905Z UID:10000272-1633431600-1633435200@brain.uci.edu SUMMARY:Dr. Eid Lien -Neurobiology and Behavior Seminar DESCRIPTION:Join the UCI Department of Neurobiology and Behavior for a virtual seminar featuring Dr. Eid Lien. URL:https://brain.uci.edu/event/dr-eid-lien-neurobiology-and-behavior-seminar/ LOCATION:CA CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/09/Dr-Eid-Lien-01-e1632934359635.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211007T100000 DTEND;TZID=America/Los_Angeles:20211007T230000 DTSTAMP:20260420T181343 CREATED:20210915T154353Z LAST-MODIFIED:20210915T154600Z UID:10000267-1633600800-1633647600@brain.uci.edu SUMMARY:Insights into Hippocampal Function from Studies of Area CA2\, Guest Speaker: Serena M. Dudek\, Ph.D. DESCRIPTION: URL:https://brain.uci.edu/event/insights-into-hippocampal-function-from-studies-of-area-ca2-guest-speaker-serena-m-dudek-ph-d/ LOCATION:Virtual Event CATEGORIES:All ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/09/Serena-M.-Dudek-PhD.jpg ORGANIZER;CN="UCI School of Medicine%2C Department of Anatomy &%3B Neurobiology":MAILTO:jdiazalo@uci.edu, lgng@hs.uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211007T110000 DTEND;TZID=America/Los_Angeles:20211007T120000 DTSTAMP:20260420T181343 CREATED:20211005T152910Z LAST-MODIFIED:20211005T152910Z UID:10000273-1633604400-1633608000@brain.uci.edu SUMMARY:UCI MIND Seminar Series: Jessica Rexach\, MD\, PhD DESCRIPTION:Functional Genomics Approach to Neuronal-Glial Mechanisms in Neurodegenerative Dementias \nJoin UCI MIND for an in-person seminar featuring Jessica Rexach\, M.D.\, Ph.D. \nJessica Rexach\, MD\, PhD \nDr. Rexach is an Assistant Professor and board certified neurologist at University of California Los Angeles. She currently holds the John Douglas French Alzheimer’s Foundation Endowed chair. Dr. Rexach studies how molecules of the immune system contribute to neurodegenerative disease. Different neurodegenerative dementias have different causal genes\, suggesting they result from distinct causal mechanisms. This includes glial and immune genes\, whose roles in the CNS are unclear. In this talk\, Dr. Rexach will highlight her recent ongoing works with the tools of functional genomics and how her lab leverages dementia genetics and genome-wide molecular disease phenotypes to generate unbiased\, data-driven models of neural-glial mechanisms of disease.  Dr. Rexach and her team use experimental systems\, including iPSC-derived spheroids and glia\, to test data-driven hypotheses in order to advance disease mechanisms and identify candidate drug targets. \nFor questions\, contact vswarup@uci.edu and bmander@hs.uci.edu URL:https://brain.uci.edu/event/uci-mind-seminar-series-jessica-rexach-md-phd/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211008T170000 DTEND;TZID=America/Los_Angeles:20211008T183000 DTSTAMP:20260420T181343 CREATED:20210929T165146Z LAST-MODIFIED:20210929T181601Z UID:10000271-1633712400-1633717800@brain.uci.edu SUMMARY:5th Annual John A. Kusske Lecture Series (Virtual) DESCRIPTION:Please join us at the 5th Annual John A. Kusske Lecture Series in honor of Dr. Kusske’s legacy.\nThe John A. Kusske Lecture was established in 2017 to honor Dr. John Kusske\, one of the former chairs of UCI School of Medicine Department of Neurological Surgery. Kusske’s dedication and valuable contributions have been instrumental in transforming the Department of Neurological Surgery into a well-established program of major national and international recognition. \n\n\n\n\n\nKeynote Speaker: \nWilliam T. Couldwell\, MD\, PhD\, FACS\,\nProfessor and Chair\, Department of Neurosurgery\nAdjunct Professor of surgery University of Utah\nPast President\, American Association of Neurological Surgeons (AANS)\nand American Academy of Neurological Surgery (AAcNS)\nLecture Title: Evolution of Skull Based Surgery\n\n\n\n  \nFree to attend but registration required\, to learn more about this event\, please visit: http://www.neurosurgery.uci.edu/kusske-lecture-series/index.asp URL:https://brain.uci.edu/event/5th-annual-john-a-kusske-lecture-series-virtual/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/09/image-5.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211012T120000 DTEND;TZID=America/Los_Angeles:20211012T130000 DTSTAMP:20260420T181343 CREATED:20210929T162728Z LAST-MODIFIED:20210929T171229Z UID:10000270-1634040000-1634043600@brain.uci.edu SUMMARY:NextGen Epilepsy Seminar: Michelle Kloc\, PhD and Megh Marathe\, PhD DESCRIPTION:Join the Department of Anatomy and Neurobiology in their NextGen Epilepsy Seminar featuring postdocs\, Michelle Kloc\, PhD\, of the University of Vermont\, and Megh Marathe\, PhD\, of UC Irvine\, who will present their latest research. \nFor more information and to RSVP please visit: https://uci.zoom.us/meeting/register/tJ0pdu6vqDoqEtR–n9oUh-DdLM9E0TpXX_0 \n  URL:https://brain.uci.edu/event/nextgen-epilepsy-seminar/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/09/image-3.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211021T130000 DTEND;TZID=America/Los_Angeles:20211021T140000 DTSTAMP:20260420T181343 CREATED:20211018T191631Z LAST-MODIFIED:20211018T211212Z UID:10000276-1634821200-1634824800@brain.uci.edu SUMMARY:NBB Graduate Student Wellness first meeting DESCRIPTION:First meeting for NBB Graduate Student Wellness. All NBB graduate students are welcome. This is an informal meeting as the committee wants to consolidate ideas on the topics and workshops to be discussed from the NBB graduate student community. Feel free to bring your lunch and coffee/tea/water/juice! URL:https://brain.uci.edu/event/nbb-graduate-student-wellness-first-meeting/ LOCATION:CNLM Courtyard\, 320 Qureshey Research Lab Irvine\, CA 92697-3800\, Irvine\, 92697-3800\, United States CATEGORIES:All,Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/hal-gatewood-OgvqXGL7XO4-unsplash-scaled.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211026T110000 DTEND;TZID=America/Los_Angeles:20211026T120000 DTSTAMP:20260420T181343 CREATED:20210929T161854Z LAST-MODIFIED:20210929T161854Z UID:10000269-1635246000-1635249600@brain.uci.edu SUMMARY:CNCM Seminar: Dr. Cris Niell DESCRIPTION:Neural circuits for natural vision \nPlease join the UCI Center for Neural Circuit Mapping in a seminar featuring Dr. Cris Niell\, Associate Professor in the Department of Biology of the University of Oregon. URL:https://brain.uci.edu/event/cncm-seminar-dr-cris-niell/ LOCATION:CA CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/09/image-2.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211102T110000 DTEND;TZID=America/Los_Angeles:20211102T120000 DTSTAMP:20260420T181343 CREATED:20211029T202712Z LAST-MODIFIED:20211029T202712Z UID:10000278-1635850800-1635854400@brain.uci.edu SUMMARY:Eve Marder\, Ph.D. DESCRIPTION:Perturbations Reveal that Degenerate Circuits Hide Cryptic Individual Variability \nThe Department of Neurobiology and Behavior will be hosting Eve Marder\, professor of biology at Brandeis University\, for a James L. McGaugh Distinguished Lecture. \nAbstract: \nMore than 40 years of work on the crustacean stomatogastric nervous system on the cardiac sac\, gastric mill\, and pyloric rhythms have described numerous instances of circuit reconfiguration by neuromodulation and sensory inputs. These reconfigurations can involve alterations in the frequency and phases relationships of rhythms\, and switching of neurons from participating in one circuit to another. Computational works shows clearly that there are multiple\, degenerate sets of parameters that can result in similar output patterns. Motivated by this\, we have studied the effects of several different perturbations on STG networks\, revealing animal-to animal differences in their responses that are not evident without extreme perturbation URL:https://brain.uci.edu/event/eve-marder-ph-d/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/marder-400.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211104T100000 DTEND;TZID=America/Los_Angeles:20211104T110000 DTSTAMP:20260420T181343 CREATED:20211012T155517Z LAST-MODIFIED:20211012T160006Z UID:10000274-1636020000-1636023600@brain.uci.edu SUMMARY:Anatomy & Neurobiology Seminar Series with Nicholas DiPatrizio\, Ph.D. DESCRIPTION:Pretty Gutsy: Endocannabinoids in the Periphery Tell Us to Eat \nHosted by Daniele Piomelli\, PhD \nThursday\, November 4\, 2021\n10 AM PT\nTelecast via Zoom\nFree to attend. Registration required. \n  URL:https://brain.uci.edu/event/anatomy-neurobiology-seminar-series-with-nicholas-dipatrizio-ph-d/ LOCATION:Virtual Event CATEGORIES:Community,Scientific ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/Nicholas-DiPatrizio-PhD.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211104T110000 DTEND;TZID=America/Los_Angeles:20211104T120000 DTSTAMP:20260420T181343 CREATED:20211101T161446Z LAST-MODIFIED:20211101T161754Z UID:10000279-1636023600-1636027200@brain.uci.edu SUMMARY:UCI MIND Seminar Series: Elizabeth Mormino\, Ph.D. DESCRIPTION:Subtyping Preclinical Alzheimer’s Disease: Typical\, Atypical\, and Resilient \nDr. Mormino is an assistant professor of Neurology at Stanford University\, and is currently serving on the Imaging Core Steering committee for the National Alzheimer’s Coordinating Center. She completed her PhD in Neuroscience at UC Berkeley in the laboratory of Dr. William Jagust\, where she performed some of the initial studies applying Amyloid PET with the tracer PIB to clinically normal older individuals. During her postdoctoral fellowship with Drs. Reisa Sperling and Keith Johnson at Massachusetts General Hospital she used multimodal imaging techniques to understand longitudinal cognitive changes among individuals classified as preclinical AD. Although amyloid abnormalities are common among clinically normal older adults\, and associated with elevated risk of future progression to clinical impairment\, we remain unable to predict future risk at the individual participant level. Although group level effects related to amyloid status are present\, trajectories of cognitive decline vary across individuals. In this talk\, Dr. Mormino will highlight her tau PET work\, which has emphasized more heterogeneity in the spatial patterns of tau PET uptake than expected. This pattern suggests that multiple subtypes exist within preclinical AD\, and that these subtypes are likely associated with distinct risk profiles (typical\, atypical\, and resilient). Subtyping preclinical AD is critical for the design of prevention trials\, as well as to establish a more complete understanding of mechanisms related to early AD processes. \nFor questions\, contact vswarup@uci.edu and bmander@hs.uci.edu URL:https://brain.uci.edu/event/uci-mind-seminar-series-elizabeth-mormino-ph-d/ LOCATION:Natural Sciences I\, 1114 Natural Sciences\, Irvine\, CA\, 92647\, United States CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/beth-mormino-hai-award.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211115T033000 DTEND;TZID=America/Los_Angeles:20211115T163000 DTSTAMP:20260420T181343 CREATED:20211110T200433Z LAST-MODIFIED:20211110T200433Z UID:10000281-1636947000-1636993800@brain.uci.edu SUMMARY:UCI MSTP Distinguished Lecture Series Talk\, Speaker: Jack Clifford\, M.D. DESCRIPTION:The Medical Scientist Training Program will be hosting an exciting talk with an accomplished clinician-scientist\, Dr. Jack Clifford on Monday\, November 15th\, 2021. Event details are below: \n  \nClifford R. Jack\, Jr.\, MD\nProfessor of Radiology\nMayo Clinic College of Medicine and Science \nA Biological Definition of Alzheimer’s Disease: NIA-AA Research Framework Present and Future \n  \nMonday\, November 15\, 2021\n3:30 – 4:30 p.m. PT \nTelecast via Zoom \n \nOrganized by: MSTP students Dhruba Banerjee\, Jacob Deyell\, Gianna Fote\, John Hong\, Heechul Jun\, Cassandra Kooiker and Yueqi Ren \nEvent Contacts: Yueqi Ren | yueqir@uci.edu\nHeechul Jun | heechulj@hs.uci.edu \nmstp.uci.edu URL:https://brain.uci.edu/event/uci-mstp-distinguished-lecture-series-talk-speaker-jack-clifford-m-d/ LOCATION:CA CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/UCI-MSTP-Distinguished-Lecture-Series-Talk-Speaker_-Jack-Clifford-M.D.-on-Monday-November-15th-2021.jpg ORGANIZER;CN="UCI School of Medicine%2C Department of Anatomy &%3B Neurobiology":MAILTO:jdiazalo@uci.edu, lgng@hs.uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211119T161000 DTEND;TZID=America/Los_Angeles:20211119T170000 DTSTAMP:20260420T181343 CREATED:20211026T165823Z LAST-MODIFIED:20211026T165823Z UID:10000277-1637338200-1637341200@brain.uci.edu SUMMARY:Conte Center Seminar: Greg Duncan\, PhD and Sonya Troller-Renfree\, PhD DESCRIPTION:The Conte Center@UCI will be hosting\, Dr. Duncan\, Distinguished Professor of Education at UCI\, and Dr. Troller-Renfree\, Postdoctoral Research Associate at Columbia University\, where they will be presenting their latest research on the impact of a poverty reduction intervention on infant brain activity. The series will be held in a virtual format. Zoom Link: https://ucihealth.zoom.us/j/91917001244?pwd=R1NRaGE0Q01RYnpqay9LWm04OWcxZz09 URL:https://brain.uci.edu/event/conte-center-seminar-greg-duncan-phd-and-sonya-troller-renfree-phd/ LOCATION:Virtual Event CATEGORIES:Community ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/Conte-Center-Seminar-Greg-Duncan-PhD-and-Sonya-Troller-Renfree-PhD.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211123T130000 DTEND;TZID=America/Los_Angeles:20211123T140000 DTSTAMP:20260420T181343 CREATED:20211015T221204Z LAST-MODIFIED:20211029T200808Z UID:10000275-1637672400-1637676000@brain.uci.edu SUMMARY:Alcohol and the Adolescent Brain\, Guest Speaker: Susan Tapert DESCRIPTION:Seminar Topic: “Alcohol & the Adolescent Brain” Host: Victoria Risbrough Tuesday\, November 23\, 2021 1:00 – 2:15PM (PDT) \n \nSusan Tapert\, Ph.D.\nProfessor and Vice Chair of Academic Affairs Department of Psychiatry UC San Diego \n  \nView the flyer below for event details. \nTapert-Flyer_Final URL:https://brain.uci.edu/event/alcohol-and-the-adolescent-brain-guest-speaker-susan-tapert/ LOCATION:Virtual Event CATEGORIES:All,Community,Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/10/Taper-Ph.D..jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211202T110000 DTEND;TZID=America/Los_Angeles:20211202T120000 DTSTAMP:20260420T181343 CREATED:20211103T213904Z LAST-MODIFIED:20211103T214548Z UID:10000280-1638442800-1638446400@brain.uci.edu SUMMARY:UCI MIND Seminar Series: Omonigho M. Bubu\, PhD DESCRIPTION:Obstructive Sleep Apnea\, Amyloid and Tau Burden\, and Alzheimer’s Disease Time-Dependent Progression \nGuest Speaker: Omonigho M. Bubu\, PhD \n\n\n\n\nDr. Bubu is an Assistant Professor and physician scientist at NYU Grossman School of Medicine\, in the Departments of Psychiatry and Population Health\, with a highly impactful programmatic research focus on sleep\, aging and Alzheimer’s disease (AD) in blacks. He did his Ph.D. from University of South Florida and a postdoctoral fellow at NYU. Dr. Bubu was awarded an NIA funded Columbia Center for Interdisciplinary Research on Alzheimer’s disease Disparities Pilot grant to conduct original research on the interaction of obstructive sleep apnea and race on plasma tau\, and neurofilament light protein. Dr. Bubu’s research focuses on examining how micro-and-macro architectural sleep changes\, and vascular risk\, impact AD risk in blacks. Alzheimer’s Disease (AD) is a neurodegenerative disease with multifactorial risk factors. Recent evidence implicates disturbed sleep as an important risk factor. This presentation will include evidence implicating obstructive sleep apnea (OSA) as a risk factor for AD\, as a physiologic marker associated with AD pathology/biomarkers (i.e. amyloid and tau)\, and as a modifier of AD risk. Results from our recent study examining whether OSA has a direct neurotoxic effect that is independent of amyloid or tau\, sufficient to induce a prospective clinical diagnosis of cognitive decline\, and whether OSA’s indirect effect that promotes amyloid or tau accumulation\, combine with OSA to act synergistically to significantly increase AD progression risk will be presented. OSA’s association with novel plasma AD biomarkers\, race and sex specific mechanisms underlying OSA-AD risk as well as future research directions will also be discussed. \n\n\nFor questions\, contact vswarup@uci.edu and bmander@hs.uci.edu URL:https://brain.uci.edu/event/obstructive-sleep-apnea-amyloid-and-tau-burden-and-alzheimers-disease-time-dependent-progression-omonigho-m-bubu-phd/ LOCATION:Virtual Event CATEGORIES:Community,Scientific ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/Obstructive-Sleep-Apnea-Amyloid-and-Tau-Burden-and-Alzheimers-Disease-Time-Dependent-Progression-Omonigho-M.-Bubu-PhD.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211202T120000 DTEND;TZID=America/Los_Angeles:20211202T130000 DTSTAMP:20260420T181343 CREATED:20211129T232932Z LAST-MODIFIED:20211129T232932Z UID:10000283-1638446400-1638450000@brain.uci.edu SUMMARY:UCI MINDcast | What is Parkinson's Disease? DESCRIPTION:Join Claire Henchcliffe\, MD\, DPhil\, Stanley van den Noort Professor and Chair of Neurology\, UCI School of Medicine on Thursday\, December 2 @ 12 PM PT for a live discussion and Q&A. Bring your questions! See you this Thursday on Facebook & YouTube LIVE. URL:https://brain.uci.edu/event/uci-mindcast-what-is-parkinsons-disease/ LOCATION:Virtual Event CATEGORIES:Community ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/Screen-Shot-2021-11-29-at-3.28.40-PM.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211202T130000 DTEND;TZID=America/Los_Angeles:20211202T203000 DTSTAMP:20260420T181343 CREATED:20211130T002728Z LAST-MODIFIED:20211130T003728Z UID:10000284-1638450000-1638477000@brain.uci.edu SUMMARY:Embodiology®: From Ancestral Movement-Music Practices to Phenomenal Being DESCRIPTION:Embodiology®: From Ancestral Movement-Music Practices to Phenomenal Being\nA Neuro-Arts Symposium Led by Professor S. Ama Wray and Professor Michael Yassa \nWhen: Dec. 2\, 1-2:15 pm and 7-8:30 pm PDT\nWhere: The Herklotz Conference Center URL:https://brain.uci.edu/event/embodiology-from-ancestral-movement-music-practices-to-phenomenal-being/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/Neuro-Arts-Symposium.jpeg ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211207T110000 DTEND;TZID=America/Los_Angeles:20211207T120000 DTSTAMP:20260420T181343 CREATED:20211112T182614Z LAST-MODIFIED:20211112T182614Z UID:10000282-1638874800-1638878400@brain.uci.edu SUMMARY:James L. McGaugh Distinguished Lecture: "A Motor Theory of Sleep Control"\, Guest Speaker: Yang Dan Ph.D. DESCRIPTION:Join us Tuesday\, December 7th\, 2021 for a James L. McGaugh Distinguished Lecture: “A Motor Theory of Sleep Control”\, Guest Speaker: Yang Dan Ph.D. from the Department of Molecular & Cell Biology at University of California Berkeley. \nHybrid Event\nNote: this event will be held virtually via Zoom and In-Person in the Herkltoz Conference Room\n \nAbstract \nTo identify neurons involved in sleep generation\, we have performed whole-brain screening for sleep active and sleep promoting neurons.  Sleep is controlled by a highly distributed network spanning the forebrain\, midbrain\, and hindbrain\, and most sleep neurons are part of the central somatic and autonomic motor circuits. The intimate association between the sleep and the two motor control networks suggests that a primary function of sleep is to promote biological processes incompatible with movement. URL:https://brain.uci.edu/event/james-l-mcgaugh-distinguished-lecture-a-motor-theory-of-sleep-control-guest-speaker-yang-dan-ph-d/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/Yang-Dan-3x2-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20211207T110000 DTEND;TZID=America/Los_Angeles:20211207T120000 DTSTAMP:20260420T181343 CREATED:20211130T195754Z LAST-MODIFIED:20211130T195754Z UID:10000285-1638874800-1638878400@brain.uci.edu SUMMARY:CNCM Seminar: Dr. Guang Yang DESCRIPTION:In vivo studies of pain-related changes of neuronal activity in the peripheral and central nervous system \nPlease join the UCI Center for Neural Circuit Mapping in a virtual seminar featuring\, Dr. Guang Yang of Columbia University. URL:https://brain.uci.edu/event/cncm-seminar-dr-guang-yang/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220111T130000 DTEND;TZID=America/Los_Angeles:20220111T140000 DTSTAMP:20260420T181343 CREATED:20211207T184944Z LAST-MODIFIED:20211207T190340Z UID:10000289-1641906000-1641909600@brain.uci.edu SUMMARY:Conte Center Seminar Series - Thomas Kash PhD DESCRIPTION:Join us Tuesday\, January 11th\, 2022 for a Conte Center@UCI Seminar: “Probing the Role of Serotonin in Alcohol Use Disorders”\, Guest Speaker: Thomas L. Kash PhD from the Department of Pharmacology at the University of North Carolina Chapel Hill. URL:https://brain.uci.edu/event/conte-center-seminar-series-thomas-kash-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/12/kash_Headshot.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220113T100000 DTEND;TZID=America/Los_Angeles:20220113T110000 DTSTAMP:20260420T181343 CREATED:20211130T202411Z LAST-MODIFIED:20211130T202411Z UID:10000287-1642068000-1642071600@brain.uci.edu SUMMARY:Pascal Kaeser\, MD DESCRIPTION:Mechanisms for Fast Dopamine Signaling \nPlease join the UCI School of Medicine Department of Anatomy and Neurobiology for a virtual seminar featuring\, Pascal Kaeser\, MD\, Associate Professor of Neurobiology of Harvard Medical School. URL:https://brain.uci.edu/event/pascal-kaeser-md/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/image-2.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20220125T110000 DTEND;TZID=UTC:20220125T120000 DTSTAMP:20260420T181343 CREATED:20210810T002846Z LAST-MODIFIED:20211018T213414Z UID:10000257-1643108400-1643112000@brain.uci.edu SUMMARY:CNLM Colloquium with Melissa Sharpe\, Ph.D. DESCRIPTION:The CNLM will be hosting\, Dr. Melissa Sharpe\, Assistant Professor of Behavioral Neuroscience at the University of California\, Los Angeles in a colloquium where she will be presenting her latest research. \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n\n\n\n\n\nThe finding that dopamine neurons support intracranial self-stimulation (ICSS) has been taken to suggest that phasic firing of dopamine neurons is reinforcing. This is one of the last findings preventing a move away from the value hypothesis of dopamine. Yet there are almost no studies investigating the cognitive basis of ICSS. We tested how dopamine stimulation is represented in the brain during ICSS. We found that physiological frequencies did not support robust ICSS or promote behavior that would indicate the stimulation was represented as a meaningful reward in a specific or general sense. However\, supraphysiological frequencies supported robust ICSS and this was associated with a representation of the stimulation as a specific sensory event that was capable of acting as a goal to motivate behavior. This demonstrates that dopamine neurons only support ICSS at supraphysiological frequencies\, and in a manner that does not reflect our subjective experience with endogenous firing of dopamine neurons during learning. These data provide important considerations for the interpretation of ICSS when used to interrogate the physiological function of dopamine and other neuronal populations. URL:https://brain.uci.edu/event/cnlm-colloquium-with-melissa-sharpe-ph-d/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-3.jpeg ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220125T110000 DTEND;TZID=America/Los_Angeles:20220125T120000 DTSTAMP:20260420T181343 CREATED:20211130T200220Z LAST-MODIFIED:20211130T200220Z UID:10000286-1643108400-1643112000@brain.uci.edu SUMMARY:CNCM Seminar: Dr. Joshua Trachtenberg DESCRIPTION:Please join the UCI Center for Neural Circuit Mapping in a seminar featuring Dr. Joshua Trachtenberg of UCLA. \nFor more information\, please visit: https://cncm.som.uci.edu/seminars/ URL:https://brain.uci.edu/event/cncm-seminar-dr-joshua-trachtenberg/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/11/image-1.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220125T120000 DTEND;TZID=America/Los_Angeles:20220125T130000 DTSTAMP:20260420T181343 CREATED:20220113T170017Z LAST-MODIFIED:20220113T170017Z UID:10000291-1643112000-1643115600@brain.uci.edu SUMMARY:What Matters to Me & Why: Leslie M. Thompson\, PhD DESCRIPTION:2021-22 UCI Health Series \nLeslie M. Thompson\, PhD\, is a Donald Bren and Chancellor’s Professor in the Departments of Psychiatry and Human Behavior and Neurobiology and Behavior at the University of California\, Irvine. \nFor more information on Dr. Thompson and the What Matters to Me & Why program\, please visit:\nhttps://chancellor.uci.edu/campus-climate/wmmw/index.php URL:https://brain.uci.edu/event/what-matters-to-me-why-leslie-m-thompson-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20220201T110000 DTEND;TZID=UTC:20220201T120000 DTSTAMP:20260420T181343 CREATED:20210810T003024Z LAST-MODIFIED:20220128T173525Z UID:10000258-1643713200-1643716800@brain.uci.edu SUMMARY:CNLM Colloquium with Barry Setlow\, Ph.D. DESCRIPTION:Sex\, drugs\, and getting old; influences on decision making and executive functions \nThe CNLM will host Dr. Barry Setlow\, professor of psychiatry at the University of Florida College of Medicine\, in a colloquium where he will present his latest research. URL:https://brain.uci.edu/event/cnlm-colloquium-with-barry-setlow-ph-d/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-4.jpeg ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220208T090000 DTEND;TZID=America/Los_Angeles:20220208T123000 DTSTAMP:20260420T181343 CREATED:20220125T220206Z LAST-MODIFIED:20220128T171840Z UID:10000292-1644310800-1644323400@brain.uci.edu SUMMARY:19th Annual EpiCenter Symposium DESCRIPTION:19th Annual EpiCenter Symposium Brain Development & Epilepsy \nThe 19th Annual EpCenter Symposium includes keynote speaker Bina Santoro\, PhD\, assistant research scientist at the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University. URL:https://brain.uci.edu/event/19th-annual-epicenter-symposium/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/image-2.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220208T110000 DTEND;TZID=America/Los_Angeles:20220208T120000 DTSTAMP:20260420T181343 CREATED:20220128T195043Z LAST-MODIFIED:20220128T214210Z UID:10000295-1644318000-1644321600@brain.uci.edu SUMMARY:Carlos Portera Cailliau\, MD DESCRIPTION:Cortical interneuron hypofunction in Fragile X Syndrome \nThe Department of Neurobiology and Behavior will host Carlos Portera Cailliau\, from the Department of Neurology & Neurobiology of the University of California\, Los Angeles\, for a James L. McGaugh Distinguished Lecture. \n  \n\nAbstract \n\nCortical circuit dysfunction is a primary pathophysiology in neurodevelopmental disorders (NDDs). Considering how symptoms in NDDs/autism become apparent in toddlers\, circuit changes must emerge very early in cortical development.  Over the last decade\, developmental differences in cortical synaptic dynamics\, neuronal adaptation\, and network synchrony have been reported in the Fmr1 knockout (KO) mouse model of Fragile X Syndrome (FXS)\, a prototypical NDD.  In addition\, the density\, maturity and activity of parvalbumin (PV) cortical interneurons are all reduced in Fmr1 KO mice and in other autism mouse models.  We find that the density of PV neurons in S1 is reduced in both juvenile and adult Fmr1 KO mice\, as well as in post-mortem tissue from human FXS cases.  Furthermore\, the density and the firing of Nkx2.1-expressing interneuron precursors are also reduced in early Fmr1 KO mice. Increasing MGE-derived interneuron activity using excitatory DREADDs significantly increases the density of PV cells at P15. Moreover\, increasing PV cell firing in Fmr1 KO mice with a novel allosteric modulator of Kv3.1 channels improves deficits in the tuning and the adaptation of excitatory neurons in S1 to repetitive whisker stimulation. URL:https://brain.uci.edu/event/carlos-portera-cailliau-md/ LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/image-4.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220210T100000 DTEND;TZID=America/Los_Angeles:20220210T110000 DTSTAMP:20260420T181344 CREATED:20220125T221957Z LAST-MODIFIED:20220128T214002Z UID:10000293-1644487200-1644490800@brain.uci.edu SUMMARY:Bruce Herring\, Ph.D. DESCRIPTION:Cell-specific expression of SAP97 links augmented glutamatergic synapse function to Schizophrenia \nJoin the Department of Anatomy & Neurobiology for a virtual seminar featuring Bruce Herring\, PhD\, assistant professor of neurobiology at the University of Southern California. URL:https://brain.uci.edu/event/bruce-herring-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/01/image-3.jpeg END:VEVENT END:VCALENDAR