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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230909T150000
DTEND;TZID=America/Los_Angeles:20230909T180000
DTSTAMP:20260419T224827
CREATED:20230621T181326Z
LAST-MODIFIED:20230621T181326Z
UID:10000413-1694271600-1694282400@brain.uci.edu
SUMMARY:Down Syndrome Showcase
DESCRIPTION:A celebration of the creative and artistic talents of children and adults with Down Syndrome and an opportunity to learn about the factors that impact the health and well-being of people with Down Syndrome \nTalent Show and Art Exhibits: Anyone with Down syndrome who would like to perform on stage or display their art/crafts should contactcoordinator@dsaoc.org. Sign-ups are on a first-come\, first-served basis. \nPoster Presentations: Any UCI student or scholar interested in presenting their scientific findings related to Down syndrome should contact ndiprosp@uci.edu. \nAdmission and parking: Free. Every guest\, performer\, and exhibitor must have a ticket. Order through the theater box office: www.thebarclay.org. \nFor more information: Visit cfar-ds.uci.edu or e-mail: cfar-ds@uci.edu  \nLight refreshments will be served. 
URL:https://brain.uci.edu/event/down-syndrome-showcase/
LOCATION:Irvine Barclay Theater\, 4242 Campus Drive\, Irvine\, CA\, 92612\, United States
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/06/down-syndrome-showcase.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230919T160000
DTEND;TZID=America/Los_Angeles:20230919T170000
DTSTAMP:20260419T224827
CREATED:20230901T182647Z
LAST-MODIFIED:20230901T205440Z
UID:10000421-1695139200-1695142800@brain.uci.edu
SUMMARY:UCI Conte Center Seminar Series with Alexander Shackman\, PhD
DESCRIPTION:Please joint the Conte Center for a lecture from Alexander Shackman\, PhD\, Associate Professor\, Department of Psychology\, University of Maryland. \nDate: September 19\, 2023\, Time: 4:00 – 5:00PM (PT)\nTitle: The Nature and Neurobiology of Anxiety\nLocation: Plumwood House (Across From Medical Education) and also Telecast via Zoom\, passcode: 764583 \nPlease reach out to James Weinstock if you have any questions (jweinsto@uci.edu).
URL:https://brain.uci.edu/event/uci-conte-center-seminar-series-with-alexander-shackman-phd/
LOCATION:Plumwood/Showa Denko Lecture Hall
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/Untitled-design-3.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231006T080000
DTEND;TZID=America/Los_Angeles:20231006T180000
DTSTAMP:20260419T224827
CREATED:20230921T172807Z
LAST-MODIFIED:20230929T192644Z
UID:10000423-1696579200-1696615200@brain.uci.edu
SUMMARY:2023 Inaugural Symposium for the UCI Center for Neurotherapeutics
DESCRIPTION:Dr. Al La Spada\, Director\, and Dr. Rob Spitale\, Associate Director\, of the UCI Center for Neurotherapeutics are delighted to announce our upcoming Inaugural Symposium: “Exploring the Future of Neurotherapeutics” \nThe goals of the Inaugural Symposium are as follows: \n\nIntroduce the center to campus. Learn about the vision that drives us\, the milestones we’ve achieved\, and our ongoing goals to further develop the center on campus.\nAn update on state-of-the-art translational neuroscience research. Internationally renowned faculty will delineate ongoing efforts to understand the complexities of the human brain and develop innovative models and solutions for neurological diseases.Lecture topics will include therapeutic drug discovery and high-throughput methods to identify novel drug targets. Experts from diverse disciplines will explain how they are tackling the challenge of delivering small molecules and biological agents across the blood-brain barrier.\nSpurring interdisciplinary collaboration across campus. One of the core values at the UCI Center for Neurotherapeutics is collaboration\, especially between faculty in the physical sciences and the biological sciences.This unique occasion will be a forum to highlight opportunities for cross-disciplinary interactions and explore potential collaborations. By combining our expertise and diverse perspectives\, we can unlock new avenues of discovery and accelerate progress toward developing novel solutions for therapy development.\n\nOur exceptional line-up of guest speakers and UCI faculty speakers include: \n\nChristopher Austin (former Director of NCATS)\nMichael Lin (Stanford University)\nJulia Schaletzky (UC Berkeley)\nRandy Ashton (University of Wisconsin)\nAnne Bang (Sanford-Burnham-Prebys Medical Research Institute)\nViviana Gradinaru (California Institute of Technology)\nAlexandre Chan (UC Irvine)\nBrian Paegel (UC Irvine)\nSzu Wang (UC Irvine)\nErrol Arkilic (UC Irvine)\n\nWhether you are a student\, postdoctoral trainee\, faculty member\, or staff member\, we encourage you to join us\, so please mark your calendars!
URL:https://brain.uci.edu/event/2023-inaugural-symposium-for-the-uci-center-for-neurotheraputics/
LOCATION:Beckman Center of the National Academies of Sciences & Engineering\, 100 Academy Wy\, Irvine\, CA\, 92617\, United States
CATEGORIES:All
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/Symposium-Email-Header.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231009T093000
DTEND;TZID=America/Los_Angeles:20231009T190000
DTSTAMP:20260419T224827
CREATED:20230804T180405Z
LAST-MODIFIED:20230804T181633Z
UID:10000416-1696843800-1696878000@brain.uci.edu
SUMMARY:AI & Biomedicine Symposium: AI and Neuroscience
DESCRIPTION:This year’s annual Southern California AI and Biomedicine Symposium will focus on AI and Neuroscience.  The event is co-sponsored by the UCI Institute for Genomics and Bioinformatics and the UCI Center for the Neurobiology of Learning and Memory. The free event includes a full day of talks\, lunch\, and reception. RSVP soon as space is limited. \nDownload Event Flyer
URL:https://brain.uci.edu/event/ai-biomedicine-symposium-ai-and-neuroscience/
LOCATION:Calit2 Auditorium\, 4100 Calit2 Building\, Irvine\, Irvine
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/08/ai-biomedical-symposium.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231017T110000
DTEND;TZID=America/Los_Angeles:20231017T120000
DTSTAMP:20260419T224827
CREATED:20230929T190105Z
LAST-MODIFIED:20231009T214316Z
UID:10000426-1697540400-1697544000@brain.uci.edu
SUMMARY:Mayank Mehta\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nHippocampus 2.0: Three simple rules \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Mayank Mehta\, professor of physics\, astronomy\, neurology\, and neurobiology at UCLA. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nThe hippocampus is implicated in many learning and memory disorders including Alzheimer’s. Dozens of drugs have cured these in mice but failed in humans. Hippocampal neurons in rodents show robust spatial selectivity. Hence\, the standard test of hippocampal function in mice is the Morris Water Maze\, an allocentric spatial memory task. However\, in freely behaving primates\, hippocampal neurons show very little spatial selectivity. Further\, hippocampal damage in humans causes profound non-spatial\, egocentric\, episodic memory deficits too\, whose neurophysiological analog in rodents is unclear. We propose a novel theory of hippocampal function\, Hippocampus 2.0\, which can reconcile these long-standing differences and provide several experimental tests of this theory. The results provide a unified framework for probing hippocampal function\, which could improve translation of therapies from mice to humans.
URL:https://brain.uci.edu/event/mayank-mehta-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/1516960566877.jpeg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231020T080000
DTEND;TZID=America/Los_Angeles:20231020T120000
DTSTAMP:20260419T224827
CREATED:20230813T233250Z
LAST-MODIFIED:20230929T190556Z
UID:10000418-1697788800-1697803200@brain.uci.edu
SUMMARY:Conspiracy Thinking in American Politics
DESCRIPTION:This Symposium will include the Annual Jerrold Post Lecture on Neuropolitics\, given by Keynote Speaker George Marcus. Psychiatrist Jerrold Post\, MD (1934-2020)\, who was Professor of Political Science at George Washington University\, was a founder of the field of political psychology and author of many influential books on the psychology of political leadership.
URL:https://brain.uci.edu/event/conspiracy-thinking-in-american-politics/
LOCATION:Virtual via Zoom\, CA
CATEGORIES:All
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/08/2023-Neuropolitics-Symposium-Header-v2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231020T150000
DTEND;TZID=America/Los_Angeles:20231020T160000
DTSTAMP:20260419T224827
CREATED:20231012T220819Z
LAST-MODIFIED:20231012T221033Z
UID:10000441-1697814000-1697817600@brain.uci.edu
SUMMARY:Samuel Barnes Science Discussion UCI Conte Center
DESCRIPTION:Join Samuel Barnes\, PhD for his discussion on “Mechanisms underlying flexible reward learning deficits in rodents” virtually with the UCI Conte Center. \nZoom Link \nPasscode: 764583
URL:https://brain.uci.edu/event/samuel-barnes-science-discussion-uci-conte-center/
LOCATION:Virtual via Zoom\, CA
CATEGORIES:All,Scientific
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/unnamed.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231024T110000
DTEND;TZID=America/Los_Angeles:20231024T120000
DTSTAMP:20260419T224827
CREATED:20230928T212745Z
LAST-MODIFIED:20231012T030909Z
UID:10000424-1698145200-1698148800@brain.uci.edu
SUMMARY:Roger Nicoll\, M.D.
DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) and the Department of Anatomy and Neurobiology for a hybrid event featuring Dr. Roger Nicoll\, professor of cellular and molecular pharmacology at the University of California\, San Francisco. \nThe Biochemistry of Memory: A (not so) New and Specific Hypothesis \nEvent is jointly sponsored through the CNLM Colloquium Series and the Anatomy and Neurobiology Seminar Series. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \n\nCaMKII and long-term potentiation (LTP) were discovered within a decade of each other and have been inextricably intertwined ever since. In 1984 Francis Crick proposed that a memory molecule should possess two properties. First\, it should be a multimeric protein with identical subunits that can phosphorylate one another. Second\, to address how memories outlast molecular turnover he proposed that naïve unphosphorylated subunits could exchange into the phosphorylated multimer and become phosphorylated. Within two years biochemical studies established that CaMKII satisfied the first prediction. Recent biochemical studies have shown that unphosphorylated CaMKII subunits can exchange into phosphorylated CaMKII multimers\, thus satisfying Crick’s second prediction. My talk will focus on linking the biochemical properties of CaMKII to LTP. I will show that the autophosphorylation of CaMKII maintains LTP (memory) by establishing a stable CaMKII/NMDA receptor complex\, resulting in the synaptic capture of AMPA receptors. LTP survives the protein turnover of CaMKII\, which is complete within 2 weeks\, by its phosphorylation of newly synthesized naïve CaMKII molecules.
URL:https://brain.uci.edu/event/roger-nicoll-m-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/09/Roger-Nicoll-464x464-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231025T120000
DTEND;TZID=America/Los_Angeles:20231025T130000
DTSTAMP:20260419T224827
CREATED:20231019T202107Z
LAST-MODIFIED:20231019T202107Z
UID:10000443-1698235200-1698238800@brain.uci.edu
SUMMARY:Effects of Narrative Structure and Agency on Memory
DESCRIPTION:The Department of Cognitive Sciences’\nColloquia Series presents: \nJanice Chen\, Ph.D.\nAssistant Professor\, Department of\nPsychological & Brain Sciences\nJohns Hopkins University \n  \nEffects of narrative structure and agency on memory \nThe world confronts our senses with a continuous stream of rapidly changing information. Yet\, we experience life as a series of episodes or events\, and in memory these pieces seem to become even further organized. How do we recall an give structure to this complex information? Recent studies have begun to examine these questions using naturalistic stimuli and behavior: subjects view audiovisual movies or read interactive stories\, then freely recount their memories of the events. Within the default network\, we find distinct brain activity patterns corresponding to individual events\, which reappear during verbal recollection; memories and neural patterns are influenced by the network structure of links between events in the narrative\, and these effects are modulated by agency. These observations construct a picture of how the brain supports our ability to comprehend and recall real-world events as they unfold continuously across time.
URL:https://brain.uci.edu/event/effects-of-narrative-structure-and-agency-on-memory/
LOCATION:Virtual via Zoom\, CA
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/Untitled-design-1-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231108T120000
DTEND;TZID=America/Los_Angeles:20231108T130000
DTSTAMP:20260419T224827
CREATED:20231103T152254Z
LAST-MODIFIED:20231103T152452Z
UID:10000447-1699444800-1699448400@brain.uci.edu
SUMMARY:Aniruddh Patel\, Ph.D.
DESCRIPTION:From the Department of Psychology at Tufts University\, Aniruddh Patel\, Ph.D. will be presenting “The Biology of the Beat: Motor Contributions to Auditory Cognitive Processing” at The Department of Cognitive Sciences’ Colloquia Series.
URL:https://brain.uci.edu/event/thethe-department-of-cognitive-sciences-colloquia-series-presents-aniruddh-patel-ph-d-the-biology-of-the-beat-motor-contributions-to-auditory-cognitive-processing/
LOCATION:Virtual via Zoom\, CA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231109T160000
DTEND;TZID=America/Los_Angeles:20231109T170000
DTSTAMP:20260419T224827
CREATED:20231027T200250Z
LAST-MODIFIED:20231027T201325Z
UID:10000445-1699545600-1699549200@brain.uci.edu
SUMMARY:Flavio Donato\, Ph.D.
DESCRIPTION:Conte Center @ UCI Seminar Series \nMemory dynamics through the divergent recruitment of developmentally-defined hippocampal traces \nJoin the Conte Center @ UCI for a seminar by Dr. Flavio Donato\, assistant professor of neurobiology at the University of Basel.
URL:https://brain.uci.edu/event/flavio-donato-ph-d/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Faculty,Scientific,Staff,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/falvio-donato.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231128T110000
DTEND;TZID=America/Los_Angeles:20231128T120000
DTSTAMP:20260419T224827
CREATED:20231009T211005Z
LAST-MODIFIED:20231009T214419Z
UID:10000429-1701169200-1701172800@brain.uci.edu
SUMMARY:Anna K. Gillespie\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nSteps toward exploring the therapeutic potential of hippocampal replay \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Anna Gillespie\, assistant professor of biological structure\, lab medicine\, and pathology at University of Washington. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \n \nDescription: \nExecuting memory-guided behavior requires storage of information about experience and later recall of that information to inform choices. Hippocampal sharp-wave ripple (SWR) events are associated with the time-compressed “replay” of representations of past experience\, and multiple correlative and causal studies have demonstrated that SWRs critically contribute to these cognitive functions. Consistent with its role in memory processes\, changes in SWRs have been reported concurrent with memory impairment in several rodent models of Alzheimer’s disease. Rescuing replay in Alzheimer’s could thus improve memory symptoms; however\, our current options for promoting physiologically relevant replay are quite limited. To address this gap\, we developed a neurofeedback paradigm for rats in which the real-time detection of SWRs triggers the delivery of positive reinforcement (food reward). In young adult animals\, this training protocol increased the prevalence of task-relevant replay during the targeted neurofeedback period by changing the temporal dynamics of SWR occurrence\, and was also associated with neural and behavioral forms of compensation after the targeted period. This work demonstrates that subjects can learn to use neurofeedback to modulate physiologically relevant patterns of hippocampal network activity and lays the foundation for future work in subjects with compromised replay\, such as rodent models of Alzheimer’s disease.
URL:https://brain.uci.edu/event/anna-k-gillespie-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/anna-gillespie-250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240116T100000
DTEND;TZID=America/Los_Angeles:20240116T110000
DTSTAMP:20260419T224827
CREATED:20240125T183718Z
LAST-MODIFIED:20240125T183828Z
UID:10000461-1705399200-1705402800@brain.uci.edu
SUMMARY:Donghui Zhu\, PhD
DESCRIPTION:SUNY Empire Innovation Professor Donghui Zhu\, PhD from Stony Brook University Presents: \n“Amyloid beta glycation leads to neuronal mitochondrial dysfunction and Alzheimer’s pathogenesis via VDAC1-dependent mtDNA efflux” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/donghui-zhu-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/donghui_zhu2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240116T160000
DTEND;TZID=America/Los_Angeles:20240116T170000
DTSTAMP:20260419T224827
CREATED:20231207T161611Z
LAST-MODIFIED:20231207T162001Z
UID:10000453-1705420800-1705424400@brain.uci.edu
SUMMARY:UCI Conte Center Seminar Series with Pat Levitt\, PhD
DESCRIPTION:“Functional Implications of Developmental Heterogeneity” by Pat Levitt\, PhD\, Chief Scientific Officer\, Senior Vice President and Director\, The Saban Research Institute\, Simms/Mann Chair in Developmental Neurogenetics\, Children’s Hospital Los Angeles\, WM Keck Provost Professor of Neurogenetics\, Keck School of Medicine of USC
URL:https://brain.uci.edu/event/uci-conte-center-seminar-series-with-pat-levitt-phd/
LOCATION:Plumwood/Showa Denko Lecture Hall
CATEGORIES:All
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2023/12/UCI-Conte-Center-Seminar-Series-with-Pat-Levitt-PhD.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240125T080000
DTEND;TZID=America/Los_Angeles:20240125T170000
DTSTAMP:20260419T224827
CREATED:20240125T235339Z
LAST-MODIFIED:20240125T235339Z
UID:10000470-1706169600-1706202000@brain.uci.edu
SUMMARY:Weizhe Hong\, PhD
DESCRIPTION:Professor of Biological Chemistry & Neurobiology Weizhe Hong\, PhD from the University of California\, Los Angeles Presents: \n“TBD” \nHybrid: ISEB 1200 & Zoom \n 
URL:https://brain.uci.edu/event/weizhe-hong-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-16.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240206T110000
DTEND;TZID=America/Los_Angeles:20240206T120000
DTSTAMP:20260419T224827
CREATED:20231009T213853Z
LAST-MODIFIED:20231205T181600Z
UID:10000431-1707217200-1707220800@brain.uci.edu
SUMMARY:Elizabeth A. Buffalo\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Elizabeth A. Buffalo\, professor and chair of physiology and biophysics at the University of Washington. \nThis event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nNeural Dynamics of Memory Formation in the Primate Hippocampus  \n \nDescription:  \nOur understanding of the hippocampus has been framed by two landmark discoveries: the discovery by Scoville and Millner that hippocampal damage causes profound and persistent amnesia and the discovery by O’Keefe and Dostrovsky of hippocampal place cells in rodents. However\, it has been unclear to what extent spatial representations are present in the primate brain and how to reconcile these representations with the known mnemonic function of this region. I will discuss a series of experiments that have examined neural activity in the hippocampus in monkeys performing behavioral tasks including foraging and spatial memory tasks in a virtual environment. These data demonstrate that behavioral task structure has a significant influence on hippocampal activity\, with neurons responding to all salient events within the task. Taken together\, these data are consistent with the idea that activity in the hippocampus tracks ongoing experience in support of memory formation.
URL:https://brain.uci.edu/event/elizabeth-buffalo-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/beth-buffalo-250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240213T110000
DTEND;TZID=America/Los_Angeles:20240213T120000
DTSTAMP:20260419T224827
CREATED:20240124T220420Z
LAST-MODIFIED:20240125T233901Z
UID:10000459-1707822000-1707825600@brain.uci.edu
SUMMARY:Katalin Gothard\, Ph.D.
DESCRIPTION:Join Dr. Katalin Gothard in the James L. McGaugh Distinguished Seminar Series In-Person or over Zoom! \n“A context-dependent switch from sensing to feeling in the primate amygdala”\n\nKatalin M. Gothard\, M.D.\, Ph.D.\nProfessor of Physiology\, Neurology\, and Neuroscience The University of Arizona College of Medicine Department of Physiology \nAbstract: \nTactile signals elicited in the periphery by social and affective touch acquire emotional significance in the brain. As the amygdala processes the valence of all sensory stimuli\, we predicted that the positive valence of grooming would strongly activate the monkey amygdala. To test this hypothesis\, we compared neural activity in the amygdala and the primary somatosensory cortex in response to social grooming and gentle airflow delivered to the same areas of the skin. Neurons in the somatosensory cortex responded to both types of tactile stimuli. In the amygdala\, however\, neurons did not respond to individual grooming sweeps even though grooming elicited autonomic states indicative of positive affect. Instead of responses to individual touch stimuli\, a large proportion of neurons showed enhanced or suppressed baseline firing rates that persisted throughout a grooming bout. These changes were attributed to social context because the presence of the groomer alone could account for increases or decreases in baseline firing rates. It appears\, therefore\, that during grooming\, the amygdala stops responding to external inputs on a short time scale but remains responsive to social context\, and the associated affective states\, on longer time scales.
URL:https://brain.uci.edu/event/james-l-mcgaugh-distinguished-seminar-series/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-6.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240215T100000
DTEND;TZID=America/Los_Angeles:20240215T110000
DTSTAMP:20260419T224827
CREATED:20240125T184404Z
LAST-MODIFIED:20240125T234347Z
UID:10000462-1707991200-1707994800@brain.uci.edu
SUMMARY:Sandeep Robert Datta\, MD\, PhD
DESCRIPTION:Professor of Neurobiology Sandeep Robert Datta\, MD\, PhD from Harvard Medical School presents: \n“Using Machine Learning to Discover How the Brain Builds Behavior” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/sandeep-robert-datta-md-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-13.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240215T110000
DTEND;TZID=America/Los_Angeles:20240215T120000
DTSTAMP:20260419T224827
CREATED:20240202T182333Z
LAST-MODIFIED:20240202T182333Z
UID:10000477-1707994800-1707998400@brain.uci.edu
SUMMARY:Garret Anderson\, PhD
DESCRIPTION:The department of Anatomy & Neurobiology will host guest speaker Garret Anderson from UC Riverside\, who will give a talk on ““Latrophilin cell-type specific expression and implications for neural circuit development”
URL:https://brain.uci.edu/event/garret-anderson-phd/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/02/Capture.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240220T100000
DTEND;TZID=America/Los_Angeles:20240220T110000
DTSTAMP:20260419T224827
CREATED:20240125T191348Z
LAST-MODIFIED:20240125T235133Z
UID:10000463-1708423200-1708426800@brain.uci.edu
SUMMARY:Michelle Jones-London\, PhD
DESCRIPTION:Chief of Office of Programs to Enhance Neuroscience Workforce Diversity Michelle Jones-London\, PhD from NIH/NINDS presents: \n“An OPEN Conversation: NINDS Strategies for Enhancing the Diversity of Neuroscience Researchers” \nHybrid: ISEB 1200 & Zoom \n 
URL:https://brain.uci.edu/event/michelle-jones-london-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-12.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240223T110000
DTEND;TZID=America/Los_Angeles:20240223T120000
DTSTAMP:20260419T224827
CREATED:20240129T160947Z
LAST-MODIFIED:20240129T161317Z
UID:10000471-1708686000-1708689600@brain.uci.edu
SUMMARY:Frances Wiseman\, PhD
DESCRIPTION:The CFAR-DS Research Seminar Series hosts scientists from UC Irvine and beyond who conduct research focused on Down syndrome\, including research ranging from human participants to animal models. This seminar series is intended for scientists\, although all are welcome to attend. \nOn Friday\, February 23\, 2024 at 11:00 am Pacific Time please join us via Zoom for a presentation by Frances Wiseman\, PhD titled “Understanding differences in Down syndrome – Alzheimer’s disease: a focus on amyloid-β formation and response.” \nFrances Wiseman\, PhD is Programme Leader for Animal Models at the UK Dementia Research Institute. Dr Wiseman will discuss her group’s recent research using combinations of Down syndrome and amyloid-β accumulation mouse models; to understand how additional copies of chromosome 21 genes other than APP may modulate Alzheimer’s disease development in people who have Down syndrome. This will include a discussion of Mumford et al 2022\, PMID: 35835549 and recent follow-up unpublished data examining the interferon amyloid-β response in a new mouse model of Down syndrome-Alzheimer’s disease.
URL:https://brain.uci.edu/event/uci-center-for-aging-research-in-down-syndrome-seminar/
LOCATION:Zoom\, Irvine\, CA\, 92697\, United States
CATEGORIES:Scientific
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/CFAR_DS-_Seminar_Wiseman_Feb2024_.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240227T100000
DTEND;TZID=America/Los_Angeles:20240227T110000
DTSTAMP:20260419T224827
CREATED:20240125T201508Z
LAST-MODIFIED:20240125T234503Z
UID:10000464-1709028000-1709031600@brain.uci.edu
SUMMARY:Yimin Zou\, PhD
DESCRIPTION:Professor in the Department of Neurobiology of UCSD Yimin Zou\, PhD presents: \n“Planar cell polarity proteins in glutamatergic synapse formation and maintenance” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/yimin-zou-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-14.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240227T160000
DTEND;TZID=America/Los_Angeles:20240227T170000
DTSTAMP:20260419T224827
CREATED:20240125T215546Z
LAST-MODIFIED:20240125T233826Z
UID:10000466-1709049600-1709053200@brain.uci.edu
SUMMARY:Seth Pollak\, PhD
DESCRIPTION:Join Seth Pollak\, PhD for his talk at the UCI Conte Center Seminar Series \n“Re-thinking Adversity: Early Life Stress from the Child’s Perspective” by Seth Pollak\, PhD\, Vaughan-Bascom Distinguished Professor\, Department of Psychology\, Pediatrics\, Anthropology; LaFollette School of Public Affairs\, University of Wisconsin – Madison
URL:https://brain.uci.edu/event/uci-conte-center-seminar-series-with-seth-pollak-phd/
LOCATION:Plumwood/Showa Denko Lecture Hall
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-9.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240305T110000
DTEND;TZID=America/Los_Angeles:20240305T120000
DTSTAMP:20260419T224827
CREATED:20231009T215006Z
LAST-MODIFIED:20240229T212335Z
UID:10000432-1709636400-1709640000@brain.uci.edu
SUMMARY:J. David Jentsch\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. J. David Jentsch\, Distinguished Professor and Chair of psychology at Binghamton University. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nDiversity to the rescue: Identifying novel molecular regulators of addiction liability
URL:https://brain.uci.edu/event/j-david-jentsch-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/jjentsch-2.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240312T100000
DTEND;TZID=America/Los_Angeles:20240312T110000
DTSTAMP:20260419T224827
CREATED:20240125T233026Z
LAST-MODIFIED:20240125T234220Z
UID:10000467-1710237600-1710241200@brain.uci.edu
SUMMARY:Keri Martinowich\, PhD
DESCRIPTION:Associate Professor\, Department of Psychiatry and Behavioral Sciences Keri Martinowich\, PhD from Johns Hopkins University Presents: \n“Cell type and spatially-resolved multiomic approaches for understanding human brain disorders” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/keri-martinowich-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-11.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240312T110000
DTEND;TZID=America/Los_Angeles:20240312T120000
DTSTAMP:20260419T224827
CREATED:20231009T215405Z
LAST-MODIFIED:20240130T163208Z
UID:10000433-1710241200-1710244800@brain.uci.edu
SUMMARY:Christian Bravo Rivera\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Christian Bravo Rivera\, assistant professor of psychiatry\, anatomy\, and neurobiology. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nNeural circuits mediating reward approach and punishment avoidance conflict  \nReward is often present in risky environments\, requiring individuals to weigh the benefits of rewards against the associated risks. There are individuals that are unable to choose an appropriate response during risky reward opportunities and thus exhibit extreme avoidance or risky behaviors that can severely impair quality of life or endanger people. It is therefore necessary to characterize how neurons mediate reward approach and threat avoidance conflict. Here\, we adapted the platform-mediated avoidance conflict task (Bravo-Rivera et al 2014; Bravo-Rivera et al 2021)\, such that water-deprived mice could nose-poke for a light-signaled water reward and avoid a tone-signaled foot-shock by stepping onto a safety platform away from the reward port. Optogenetic activation of GABAergic neurons in the ventral pallidum invigorated reward approach at the expense of receiving shocks. Photometry recordings of glutamatergic neurons in the ventral pallidum and in the lateral habenula during conflict revealed that these structures promote avoidance and become inhibited during conflicted reward approach. These results suggest that a pallidal-habenula circuit mediates motivational conflict. We also compared behavioral conflict in male and female mice. Interestingly\, females stepped on the platform earlier than males after tone onset and took longer to leave the platform after tone offset. Males received more shocks than females and received more water reward than females by the end conflict training. Moreover\, females exhibited more tone-induced freezing and exhibited more frequent darting than males. These results suggest that females exhibit more avoidance behavior and less reward approach than males in the face of approach/avoidance conflict.
URL:https://brain.uci.edu/event/christian-bravo-rivera-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2023/10/christian-bravo-rivera250.jpg
ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240313T120000
DTEND;TZID=America/Los_Angeles:20240313T130000
DTSTAMP:20260419T224827
CREATED:20240307T161631Z
LAST-MODIFIED:20240307T163003Z
UID:10000511-1710331200-1710334800@brain.uci.edu
SUMMARY:Robert Zatorre\, PhD
DESCRIPTION:The Department of  Cognitive Sciences’ Colloquia Series presents guest speaker Dr. Robert Zatorre\, a professor in the Department of Psychology at Montreal Neurological Institute\, McGill University. \nFrom Perception to Pleasure. The Neuroscience of Music and Why We Love It \nMusic has existed in human societies since prehistory\, likely because it allows expression and regulation of emotion\, and evokes pleasure. In this lecture I will present findings from cognitive neuroscience that bear on the question of how we get from perception of sound patterns to pleasurable responses. I will first discuss evidence that corticocortical loops from and to the auditory cortex are responsible not only for perceptual processes but also for working memory\, sensory-motor\, and predictive functions that are essential to produce and perceive music. Then\, I will discuss neuroimaging and brain modulation studies from our lab focusing on the dopaminergic reward system\, its involvement in musical pleasure\, and what happens when that system is disrupted. I propose that pleasure in music arises from interactions between cortical loops that enable expectancies to emerge from perceived sound patterns\, and subcortical systems responsible for reward and valuation. This model integrates knowledge derived from basic neuroscience of reward mechanisms with independently derived concepts\, such as tension and anticipation\, from music theory. It may also serve as a way of thinking more broadly about aesthetic rewards.
URL:https://brain.uci.edu/event/robert-zatorre-phd/
LOCATION:Virtual via Zoom\, CA
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240314T110000
DTEND;TZID=America/Los_Angeles:20240314T120000
DTSTAMP:20260419T224827
CREATED:20240208T235302Z
LAST-MODIFIED:20240209T161652Z
UID:10000494-1710414000-1710417600@brain.uci.edu
SUMMARY:Krishna Jayant\, PhD
DESCRIPTION:The department of Anatomy & Neurobiology will host guest speaker Dr. Krishna Jayant\, an assistant professor from Purdue University. \nA translaminar space-time code supports touch-evoked traveling waves \nTraveling waves in mammalian cortex mediate vital aspects of animal cognition\, such as stimuli perception and working memory. Theoretical results suggest that these waves preserve timing and are critical for plasticity across long-range neural circuits. Therefore\, revealing the circuit mechanisms underlying sensory-evoked traveling waves is critical to understanding the neural basis of sensory perception. In this talk\, I will describe our recent efforts in using 2D nanotextured transparent ECoG style electrodes to map circuits orchestrating wave dynamics. Specifically\, by simultaneously mapping local-field-potentials and cellular ensemble dynamics (via 2P calcium imaging)\, we will describe the circuit features tied to traveling waves under active and passive whisker touch. We will show that in awake mice\, both passive and active whisker touch elicited traveling waves within and across barrels\, with both an early and late component lasting hundreds of milliseconds.  Strikingly\, wave dynamics reflected the value of the tactile stimulus\, and was found to be shaped by reinforcement learning. We will also describe how the late wave component is i) strongly modulated by motor feedback\, ii) complements a sparse ensemble pattern across layer 2/3 which we resolved via a balanced-state network model with distributed top-down feedback\, and iii) aligns with regenerative Layer 5 apical dendritic Ca2+ spikes. Our results establish a model in which translaminar spacetime patterns\, organized by motor cortical feedback\, sculpt touch-evoked traveling waves.
URL:https://brain.uci.edu/event/krishna-jayant-phd/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/02/Untitled-design-48.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240315T120000
DTEND;TZID=America/Los_Angeles:20240315T131500
DTSTAMP:20260419T224827
CREATED:20240131T220057Z
LAST-MODIFIED:20240131T220057Z
UID:10000472-1710504000-1710508500@brain.uci.edu
SUMMARY:Presidential Leadership and Disability
DESCRIPTION:The age of presidential candidates has become a salient concern\, but age is not the only physical factor that should concern citizens. Presidents can also suffer various forms of illness\, both physical and psychological. This talk highlights the nature of these concerns and how we might work to mitigate their impact on political outcomes. \nFree registration is open now: https://uci.zoom.us/webinar/register/WN_m5HtweYgSh6t9sGnAa_hOQ#/registration \nFor more details\, please visit: https://sites.uci.edu/centerforneuropolitics/
URL:https://brain.uci.edu/event/presidential-leadership-and-disability/
LOCATION:Zoom Webinar
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Neuropolitics-Social-Ad_FridayMarch5th2024_-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240319T100000
DTEND;TZID=America/Los_Angeles:20240319T110000
DTSTAMP:20260419T224827
CREATED:20240125T233442Z
LAST-MODIFIED:20240125T234139Z
UID:10000468-1710842400-1710846000@brain.uci.edu
SUMMARY:Anubhuti Goel\, PhD
DESCRIPTION:Assistant Professor of the Department of Psychology Anubhuti Goel\, PhD from UC Riverside Presents: \n“TBD” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/anubhuti-goel-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-10.png
END:VEVENT
END:VCALENDAR