ASK THE DOC: Malcolm Dick, Ph.D.
2019-10-04 09:00 - 10:00 (America/Los_Angeles) | Irvine, CA, 92697, United States
ASK THE DOC: Alzheimer’s Research Today is an informative Facebook Live video series focused on the most pressing questions and latest research in the fight against Alzheimer’s disease. Presented by a panel of experts from UCI MIND, this series is scheduled for the first Friday of each month from 9:00-9:30AM PST at @UCIrvineMIND on Facebook.

Southern California Biomedical Imaging and Machine Learning Symposium
2019-10-04 09:30 - 17:00 | Irvine, CA, 92697, United States
This free, one-day symposium includes talks by UCI, UCLA and USC speakers. The Southern California Biomedical Imaging and Machine Learning Symposium is sponsored by UCI’s Institute for Genomics and Bioinformatics.

ASK THE DOC @ Fullerton Public Library
2019-10-07 18:00 - 19:00 | Irvine, CA, 92697, United States
Do you have questions about brain health, memory changes, and Alzheimer’s disease? Ask the experts from UCI MIND, Orange County’s only congressionally designated Alzheimer’s Disease Research Center. Panelists will answer your most pressing questions during this free community Q&A session.

The Irvine Center for Addiction Neuroscience Symposium
2019-10-14 08:00 - 17:00 | Irvine, CA, 92697, United States
Join us for the Irvine Center for Addiction Neuroscience (ICAN) Symposium on October 14th, 2019. Over a billion individuals have substance use disorders across the world .ICAN aims to reduce substance use disorders through the promotion and development of sustained translational addiction research.

Kendall Lee, MD, PhD
2019-10-14 16:00 - 17:00 | Irvine, CA, 92697, United States
Dr. Kendall Lee, Professor and Director at the Neural Engineering Laboratory in the Department of Neurosurgery at the Mayo Clinic, will present ‘Neural Engineering: Next Generation of Electroceuticals.’

McGaugh-Gerard Lecture on Learning and Memory 2019
2019-10-14 19:30 - 20:30 | Irvine, CA, 92697, United States
Daniel L. Schacter is the William R. Kenan, Jr. Professor of Psychology at Harvard University. Schacter’s research explores the relation between conscious and unconscious forms of memory, the nature of memory distortions, how individuals use memory to imagine possible future events, enhancement of online learning, as well as the effects of aging on memory.
The McGaugh-Gerard lectures are made possible by the McGaugh-Gerard Endowment that was established by Dr. James L. McGaugh and the family trust of the late Dr. Ralph W. Gerard. The lectures are free to the public and are intended to encourage public education, scientific discourse and exposure to world class science.

Juan Fortea, M.D., Ph.D.
2019-10-24 11:00 - 12:00 | Irvine, CA, 92697, United States
“Alzheimer’s disease in Down syndrome and familial Alzheimer’s disease: Unique opportunities to understand and prevent a devastating disease”
Juan Fortea, M.D., Ph.D.
Alzheimer Down Unit Director
Hospital of Sant Pau and Catalan Foundation for Down Syndrome

30th Annual SoCal Alzheimer’s Disease Research Conference
2019-10-25 07:30 - 16:00 | Irvine, CA, 92697, United States
Join national experts for the 30th Annual SoCal Alzheimer’s Disease Research Conference on Friday, October 25th at the Irvine Marriott Hotel.How close are we to solving Alzheimer’s disease? What have we learned so far? Where do we go from here? For 30 years, the Annual SoCal Alzheimer’s Disease Research Conference has delivered the latest knowledge in dementia research and care to the Orange County community. In its Pearl Anniversary, join national experts as they explore what we have discovered and charge forward with hope for solutions!

UCI Interdisciplinary Research Showcase and Workshop
2019-10-25 13:00 - 18:00 | Irvine, CA, 92697, United States
Faculty and graduate students are invited to join in this new workshop designed to celebrate and promote effective collaboration in interdisciplinary research.
Workshop sessions will address a wide range of topics of interest to UCI researchers, including hands-on tools for promoting effective cross-disciplinary collaboration and best practices for leading and sustaining interdisciplinary research and training programs.

Learning and Using Two Languages May Change Your Mind
2019-10-28 12:00 - 13:00 | Irvine, CA, 92697, United States
Judith F. Kroll

Distinguished Professor
Department of Language Science
University of California, Irvine
Monday, October 28, 2019 12:00 – 1:15 pm, Education 2010

ASK THE DOC: Maria Corrada, ScM, ScD
2019-11-01 09:00 - 10:00 | CA
ASK THE DOC: Alzheimer’s Research Today is an informative Facebook Live video series focused on the most pressing questions and latest research in the fight against Alzheimer’s disease. Presented by a panel of experts from UCI MIND, this series is scheduled for the first Friday of each month from 9:00-9:30AM PST at @UCIrvineMIND on Facebook.

Will I Get Alzheimer’s If I Live Long Enough?
with Maria Corrada

Shreesh P. Mysore, Ph.D.
2019-11-06 12:00 - 13:00 | Irvine, CA, 92697, United States
Despite the rich literature on the consequences of selective attention to behavior and to neural responses, as well as a wealth of models of competitive selection, little is known about the circuit mechanisms by which the brain actually selects the highest priority stimulus as the next target of spatial attention. Following a first principles approach that breaks down selection into computational primitives, and with experiments in the barn owl midbrain selection network, Dr. Mysore and team recently discovered neural circuit mechanisms for categorical (robust-to-noise) selection as well as location-invariant selection (selection at all possible pairs of locations). Dr. Mysore shall describe these findings, and in doing so, highlight (a) the identification of a new form of population coding in the brain, namely, combinatorially optimized coding (relating to classic np-hard optimization problems), as well as of (b) a novel, multi-holed donut-like organization of inhibition in the brain. He shall then switch gears and describe their development of primate-like behavioral paradigms for the study of endogenous as well as exogenous control of visuospatial selective attention in freely behaving mice. He shall end with early results from their efforts involving endoscopic calcium imaging and optogenetic manipulations in mice that are aimed at identifying circuit mechanisms of selection for spatial attention in mammals.

Davide Dulcis, Ph.D.
2019-11-07 11:00 - 12:00 | Irvine, CA, 92697, United States
Dr. Dulcis is an Associate Professor of Psychiatry at UCSD. He is a faculty member of the Neurosciences graduate program and the Center for Circadian Biology at UCSD. He received his B.S. from University of Cagliari (Italy) double majoring in Physiology and Biology. While earning his Ph.D. from University of Arizona in Neuroscience, he illustrated the role of neurotransmitters in cardiac function of neurogenic invertebrate hearts. During his post-doctoral training in Neurobiology at UCSD, he discovered that neurotransmitters can be respecified by sensory stimuli, with matching respecification of postsynaptic receptor expression and associated changes in behavior (Nature, 2008; Science, 2013; Neuron, 2017).

Robert Hunt, Ph.D.
2019-11-12 11:00 - 12:00 | Irvine, CA, 92697, United States
Interneurons and the control of memory precision
Inhibitory interneurons govern the sparse activation of principal cells that permits appropriate behaviors, and they are activated during specific memory processes. Our recent work has demonstrated important roles for interneurons in disorders of brain development and injury. These studies have motivated our ongoing efforts to understand how these cells operate at the synaptic, circuit and behavioral levels and in designing new technologies targeting specific populations of interneurons for therapy. I will discuss our recent efforts examining the role of interneurons in memory disorders and in designing cell-based therapies that enable precise manipulation of inhibitory circuits in the brain.

Francesco Battaglia, Ph.D.
2019-11-14 11:00 - 12:00 | Irvine, CA, 92697, United States
Cortico-hippocampal interactions for memory
Francesco Battaglia, PhD, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen
Memory representations are evolving objects through the lifetime of a memory. The recording of large groups of neurons from behaving animals has been instrumental for investigating brain network dynamics supporting memory encoding consolidation and retrieval. Classically, upon memory encoding during active behavior, hippocampal activity is dominated by theta oscillations. During inactivity, hippocampal neurons burst synchronously, constituting sharp waves, which can propagate to other structures, theoretically supporting memory consolidation. The PFC is one prominent target. This ‘two-stage’ model has been updated by new data from high-density electrophysiological recordings in animals that shed light on how information is encoded and exchanged between hippocampus and PFC. I will present an overview of this field focusing on results from my lab on cortico-hippocampal dynamics, including new theoretical and experimental developments. I will show how functional connectivity reconstruction based on Maximum Entropy methods can uncover changes in the prefrontal neural network that are linked to learning, and how these cortical functional network responds to hippocampal sharp waves. The link between cortical functional networks and hippocampal sharp waves correlates with animal’s performance in the behavioral task. In order to better delineate this link, we designed a novel behavioral task, the “object-space” task, which allows to compare episodic-like memory acquisition, with memory acquired by accumulation across multiple episodes, while the basic behavioral sequence is very similar and comparable across conditions.

Richard G. Ellenbogen, MD, FACS
2019-11-15 17:00 - 19:30 | Irvine, CA, 92697, United States
The 3rd Annual John A. Kusske Lecture Series
Richard G. Ellenbogen, MD, FACS
The Myth of Equipoise
Theodore S. Roberts Professor
Chair and Residency Program Director Department of Neurological Surgery University of Washington
RSVP to Cindy Wang at ucineurosurgery@hs.uci.edu or 714-456-3402. Seating is limited.

The 9th Annual Arnold Starr Lecture and Exhibition
2019-11-20 17:00 - 20:30 | Irvine, CA, 92697, United States
Mechanisms of Auditory Neuropathy
Guest Lecture by Maoli Duan, MD, PhD, Karolinska Institute, Sweden
Lecture (6:00 – 7:00 p.m.) will be live-streamed and has been approved for AMA PRA Category 1 Credit
Artists & Friends Dinner (7:00 – 8:30 p.m.) $100 single; $150 couple

UCI Brain Initiative Launch Event
2019-11-21 08:00 - 20:00 | Irvine, CA, 92697, United States
UCI faculty, staff, and students are invited to join UCI Brain for a day of discussions about team science, presentations by groups of UCI faculty and students, along with a special keynote presentation by Dr. Ralph Greenspan, associate director of the Kavli Institute for the Brain and Mind.
During this event, UCI Brain will be sharing two new opportunities for UCI faculty:

Pilot Grants of up to $25,000
Dimensions Team Science Development Tool

In the evening, the community will be invited to a fireside chat with UCI’s most distinguished neuroscience faculty.
Invite your friends on Facebook!

Michael Halassa, M.D., Ph.D.
2019-11-21 16:00 - 17:00 | Irvine, CA, 92697, United States
Networks Underlying Cognitive Control & Flexibility
Michael Halassa is a MIT neuroscientist who aims to understand the basic circuit mechanisms of how information is routed in the brain and how disruptions in these circuits can lead to neurological and psychiatric disorders. As a practicing psychiatrist he aims to develop novel approaches to diagnosing and treating these illnesses guided by insights both from the lab and clinic.

How Will Brain Science Shape Your Future?
2019-11-21 18:00 - 20:00 | Irvine, CA, 92697, United States
How Will Brain Science Shape Your Future?
Fireside chat with UCI’s leading brain scientists
6-8 p.m. with a reception beginning at 5 p.m.
The Beckman Center of the National Academies of Sciences and Engineering (directions)
Please note that registering online does not guarantee a seat. Early arrival is strongly encouraged.

2019 Parkinson’s Symposium
2019-11-23 08:00 - 13:00 | Irvine, CA, 92697, United States
Treatment Options in Parkinson’s Disease: From Behavior to Movement
Join UCI Health for a special symposium about Parkinson’s disease, including a discussion
on behavioral symptoms, current and recent developments in medical and surgical therapies for Parkinson’s Disease. Visit ucihealth.org/parkinsonsevent to register.

Elena Blanco-Suárez, PhD
2019-11-25 09:00 - 10:00 | Irvine, CA, 92697, United States

Javier Diaz Alonso, PhD
2019-11-25 10:00 - 11:30 | Irvine, CA, 92697, United States

Gucan Dai, PhD
2019-11-25 11:30 - 12:30 | Irvine, CA, 92697, United States

Distinguished Language Scientist Colloquium
2019-12-02 11:00 - 12:30 | Irvine, CA, 92697, United States
The Neurobiology of reading in deaf and hearing adults
The UCI Program in Language Science will host Karen Emmorey from the School of Speech, Language, and Hearing Sciences at San Diego State University.
Recent neuroimaging and neurophysiological evidence reveals how the reading system successfully adapts when phonological codes are relatively coarse-grained due to reduced or distorted auditory input. Our research focuses on deaf adults who have achieved reading success and how use sign language in their everyday lives.

ASK THE DOC: Ira Lott, MD
2019-12-06 09:00 - 09:30 | CA
ASK THE DOC: Alzheimer’s Research Today is an informative Facebook Live video series focused on the most pressing questions and latest research in the fight against Alzheimer’s disease. Presented by a panel of experts from UCI MIND, this series is scheduled for the first Friday of each month from 9:00-9:30AM PST at @UCIrvineMIND on Facebook.
What Is the Link Between Down Syndrome and Alzheimer’s?
with Ira Lott, MD

Stem Cell and Regenerative Medicine Symposium
2019-12-09 09:00 - 16:30 | Irvine, CA, 92697, United States

Stephan Feske, MD.
2019-12-12 16:00 - 17:00 | Irvine, CA, 92697, United States
UCI Medical Scientist Training Program Distinguished Lecture Series
Ion Channels as Critical Regulators of Immunity
Dr. Stephan Feske’s research focuses on signaling pathways in cells of the immune system, particularly store-operated calcium entry (SOCE), mediated by the calcium release–activated calcium (CRAC) channel, and other ion channels.
The Feske lab investigates how CRAC channels are activated, how they affect cell physiology, and how calcium signals control immune function in the contexts of infection, autoimmunity, and cancer.

Why do Alzheimer's disease clinical trials fail?
2020-01-10 11:00 - 11:30 | Irvine, CA, 92697, United States
Live online Q&A with Joshua Grill, PhD, Associate Professor of Psychiatry & Human Behavior and Neurobiology & Behavior. Attend the video live on our Facebook page or view archived episodes on our YouTube channel.

MSTP 35th Annual Distinguished Lecture Series
2020-01-13 16:00 - 17:00 | Irvine, CA, 92697, United States
A critical role for lysomes in neurodegenerative disease.
The 35th MSTP Annual Distinguished Lecture will feature Aimee Kao, MD, PhD, a professor of neurobiology at the University of California, San Francisco.
