BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Brain - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Brain X-ORIGINAL-URL:https://brain.uci.edu X-WR-CALDESC:Events for Brain REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/Los_Angeles BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20210314T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20211107T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20220313T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20221106T090000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT DTSTART:20230312T100000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0700 TZOFFSETTO:-0800 TZNAME:PST DTSTART:20231105T090000 END:STANDARD END:VTIMEZONE BEGIN:VTIMEZONE TZID:UTC BEGIN:STANDARD TZOFFSETFROM:+0000 TZOFFSETTO:+0000 TZNAME:UTC DTSTART:20210101T000000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220505T090000 DTEND;TZID=America/Los_Angeles:20220506T150000 DTSTAMP:20260417T161157 CREATED:20210824T213007Z LAST-MODIFIED:20220314T172921Z UID:10000262-1651741200-1651849200@brain.uci.edu SUMMARY:2022 CNLM Spring Conference DESCRIPTION:Since 1982\, the CNLM has hosted an annual scientific conference in the spring to discuss recent advances in the field and launch new collaborations and synergies. The conferences include several themed symposia\, short presentations by trainees\, panel discussions\, and keynote lectures. It is a crucial scientific development opportunity for students and postdocs as well as a faculty. Attendance is by invitation only (except for the triennial international conference – see 2018 below)\, and the program is developed by a committee of CNLM faculty fellows\, including external fellows. The conferences are highly renowned for their intellectual atmosphere\, use of the 50/50 discussion rule\, and the special edited volumes that result from them. Typical attendance at the annual conference is between 100-120 attendees. Attendance at the 2018 meeting exceeded 1\,000 scientists.  \nTo learn more about past conferences\, visit: https://cnlm.uci.edu/scientific-activities/spring-meeting/ URL:https://brain.uci.edu/event/2022-cnlm-spring-conference/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/SpringConferenceGraphics_FinalRevised-01.png ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220509T160000 DTEND;TZID=America/Los_Angeles:20220509T170000 DTSTAMP:20260417T161157 CREATED:20220415T235725Z LAST-MODIFIED:20220426T202011Z UID:10000316-1652112000-1652115600@brain.uci.edu SUMMARY:Conte Center Seminar Series - Mathias V. Schmidt - Max Planck Institute of Psychiatry DESCRIPTION:Mathias V. Schmidt\, Ph.D.\nResearch Group Leader\nMax Planck Institute of Psychiatry\n\n\n\nRoutes to Enhance Stress Resilience: Manipulation of Genes or Environment\nHost: Tallie Z. Baram\, MD\, PhD \nMonday\, May 9th\, 2022\, 4 – 5 p.m. PT \nIn-person at Gross Hall 4th Floor Conference Room \nRefreshments and Pastries to be provided \nAlso will be Telecast via Zoom \n \nEvent Contact: James Weinstock | jweinsto@hs.uci.edu URL:https://brain.uci.edu/event/conte-center-seminar-series-mathias-v-schmidt-max-planck-institute-of-psychiatry/ LOCATION:Virtual/Hybrid Event (In person at Gross Hall 4th Floor Conference Room)\, Irvine\, CA\, 92697\, United States CATEGORIES:All ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/Headshot.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220510T100000 DTEND;TZID=America/Los_Angeles:20220510T110000 DTSTAMP:20260417T161157 CREATED:20220420T212604Z LAST-MODIFIED:20220420T212604Z UID:10000317-1652176800-1652180400@brain.uci.edu SUMMARY:Jonathan Ting\, PhD DESCRIPTION:New opportunities for primate cellular neuroscience in the era of single cell genomics \nJoin the UCI Center for Neural Circuit Mapping for a hybrid seminar with Dr. Jonathan Ting from the Allen Institute for Brain Science. \nAbstract: \nHow many cell types exist in the brain and what are their unique functional properties?  Single cell transcriptomics provides a means to define discrete cell classes\, subclasses and types on the basis of gene expression signatures.  This approach has revolutionized neuroscience by providing foundational cell type taxonomies with unprecedented resolution and has led to the identification of previously unknown brain cell types.  In addition\, analytical tools enable precise alignment across diverse cell type taxonomies\, for example\, mapping of cell type homologies across species.  Such approaches will no doubt deepen our understanding of the evolution of brain cell types.  As a direct outcome of this progress\, a new challenge for the neuroscience field is to explore the unique cellular properties of these myriad brain cell types\, and to experimentally address whether transcriptomically distinct cell types serve functionally distinct roles in brain circuits.  Towards this aspirational goal\, how can we leverage the richness of single cell transcriptomics and epigenomics to target and manipulate this overwhelming diversity of brain cell types and across widely utilized mammalian model organisms?  In this talk I will describe the various projects and strategies my colleagues and I have developed at the Allen Institute to address these outstanding challenges\, with particular attention to creating new opportunities for primate cellular neuroscience.  I will focus on our published and unpublished biological discoveries coming from Patch-seq experiments exploring signature electrophysiological and morphological properties of transcripomically-identified primate neocortical cell types\, as well as the early implementation of first-in-class viral genetic tools for targeting brain cell types. \n  \nFor those registering for in-person there is a 22 max capacity. In addition\, to receiving your zoom virtual registration link\, you will receive a separate email reminder that you registered for the in-person. URL:https://brain.uci.edu/event/jonathan-ting-phd/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/image-1.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220510T190000 DTEND;TZID=America/Los_Angeles:20220510T200000 DTSTAMP:20260417T161157 CREATED:20220509T193505Z LAST-MODIFIED:20220509T193610Z UID:10000323-1652209200-1652212800@brain.uci.edu SUMMARY:Neuro-ophthalmology with Vivek R. Patel\, MD DESCRIPTION:Join the Gavin Herbert Eye Institute for a virtual community lecture in which Vivek R. Patel\, MD\, will talk about neuro-ophthalmology. URL:https://brain.uci.edu/event/neuro-ophthalmology/ LOCATION:Virtual Event CATEGORIES:All,Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-1.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220510T190000 DTEND;TZID=America/Los_Angeles:20220510T200000 DTSTAMP:20260417T161157 CREATED:20220509T192835Z LAST-MODIFIED:20220509T192835Z UID:10000322-1652209200-1652212800@brain.uci.edu SUMMARY:Craig Walsh\, PhD DESCRIPTION:The Impact of T Cells in Neurodegenerative Disease and Regenerative Therapies \nThis hybrid lecture will be held both in-person and online. If you would like to attend the lecture in person\, register here for the location details. \nCraig Walsh\, PhD\nDr. Walsh is a Professor of Molecular Biology and Biochemistry\, Co-Director of the Institute for Immunology\, Director of the Multiple Sclerosis Research Center and a Member of the Cancer Research Institute. \nHis research focuses on the role apoptotic signal transduction plays in the development\, activation and homeostasis of the immune system. Current interests include the study of death-receptors and the regulation of T cell activation. URL:https://brain.uci.edu/event/craig-walsh-phd/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220512T100000 DTEND;TZID=America/Los_Angeles:20220512T110000 DTSTAMP:20260417T161157 CREATED:20220420T213355Z LAST-MODIFIED:20220420T213355Z UID:10000318-1652349600-1652353200@brain.uci.edu SUMMARY:Thomas A. Blanpied\, PhD DESCRIPTION:Dynamic control of synaptic nanostructure and function \nThe 2021 – 2022 Anatomy & Neurobiology Seminar Series presents\, Thomas A. Blanpied\, PhD\, Professor of Physiology from the University of Maryland School of Medicine\, in a virtual seminar where he will present his latest research. \n  URL:https://brain.uci.edu/event/thomas-a-blanpied-phd/ CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/Blanpied_Thomas.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20220517T110000 DTEND;TZID=UTC:20220517T120000 DTSTAMP:20260417T161157 CREATED:20210810T003628Z LAST-MODIFIED:20210928T155150Z UID:10000261-1652785200-1652788800@brain.uci.edu SUMMARY:CNLM Colloquium with Juliet Davidow\, Ph.D. DESCRIPTION:Adolescent learning and goal-directed behavior \nThe CNLM will be hosting Juliet Davidow\, Ph.D.\,  Assistant Professor of Psychology at Northeastern University\, in a colloquium where she will present her latest research. \nAbstract:  \nAdolescence is a time of dynamic psychological and brain development. Previous research has shown that normative shifts in motivational processes during adolescence can relate to negative outcomes from risky actions\, driven by biased interactions among the brain’s striatocortical circuitry. However\, these brain systems support a range of functions\, including learning and goal-directed action selection. Could motivational and neurodevelopmental change during adolescence confer learning advantages? My work highlights how development of multiple learning and control systems in the brain contribute to different aspects of behavior\, associated with both benefits and costs in performance. Using fMRI and computational modeling approaches\, we revealed that adolescents can engage in better learning strategies compared to adults\, a behavioral profile that is supported by stronger interactions between the striatum and the hippocampus. However\, when contextual demands change\, stronger learning can become disadvantageous\, such as when previous learning interacts with inhibitory control – a set of processes supported by coordination among late-developing lateral and medial prefrontal cortical regions. Taken together\, we illustrate both the advantages and challenges that arise from emerging functional orchestration of the brain during adolescence. This work contributes to the characterization of this time of transition from childhood to adulthood. \nThis year\, the series will be held in a virtual format with some speakers presenting in-person as well. We will keep registered participants updated on the possibility of an in-person event as the situation with COVID-19 evolves. \n\n  URL:https://brain.uci.edu/event/cnlm-colloquium-with-juliet-davidow-ph-d/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:Scientific,Staff,Students,Students, Faculty, Staff Only ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2021/08/image-6.jpeg ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220524T110000 DTEND;TZID=America/Los_Angeles:20220524T120000 DTSTAMP:20260417T161157 CREATED:20220523T191520Z LAST-MODIFIED:20220523T191713Z UID:10000325-1653390000-1653393600@brain.uci.edu SUMMARY:Ted Abel\, PhD DESCRIPTION:James L. McGaugh Distinguished Lecture \nMolecular Mechanisms of Long-Term Memory Storage \nPlease join the UCI Department of Neurobiology and Behavior in a hybrid event featuring Dr. Ted Abel of the Iowa Neuroscience Institute from the University of Iowa. \n \nAbstract: Research in the Abel lab at the University of Iowa focuses on the molecular mechanisms underlying the persistence of memory.  New experiences are initially encoded as labile short-term memories\, which are converted into stable long-term memory by gene transcription-dependent processes during memory consolidation.  In the hours after learning\, the induction of gene expression follows a specific pattern that involves transient waves of transcriptional activity\, which are needed for memory consolidation. This transcriptional regulation is meditated by epigenomic mechanisms such as histone acetylation. These epigenetic modifications are critical for the long-lasting regulation of gene expression during development and may be a major mechanism of information storage in the brain. Changes in these epigenetic modifications contribute to impairments in synaptic plasticity and cognitive function associated with many neurodevelopmental and neuropsychiatric disorders. Histone acetylation in an important epigenetic mark\, and we have shown that the metabolic enzyme acetyl-CoA synthetase 2 (ACSS2) directly regulates histone acetylation important for long-term spatial memory. ACSS2 is present in the nucleus where it generates acetyl co-A ‘on-site’ at chromatin for histone acetylation and the transcription of key neuronal genes. A critical question has been to identify the genes targeted by these epigenetic regulatory processes. The NR4A “orphan” nuclear receptors are important targets of epigenetic mechanisms mediating memory storage\, and they act as molecular switches for long-term memory storage. In our recent work\, we have shown we have found that NR4A proteins regulate the transcription of genes encoding chaperones that localize to the endoplasmic reticulum (ER). These chaperones function to traffic plasticity-related proteins to the cell surface during long lasting forms of synaptic plasticity and memory. Our understanding of the transcriptional cascades that mediate the consolidation and storage of long- term memory may ultimately lead to the development of new treatments for the debilitating cognitive deficits associated with neuropsychiatric\, neurodevelopmental\, and neurodegenerative disorders. URL:https://brain.uci.edu/event/ted-abel-phd/ LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom CATEGORIES:All,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-3-scaled-e1653333376368.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220525T150000 DTEND;TZID=America/Los_Angeles:20220525T170000 DTSTAMP:20260417T161157 CREATED:20220207T185913Z LAST-MODIFIED:20220216T000055Z UID:10000296-1653490800-1653498000@brain.uci.edu SUMMARY:2022 CNLM Awards Ceremony DESCRIPTION:Join the Center for the Neurobiology of Learning and Memory (CNLM) for the 2021 CNLM Awards Ceremony The CNLM offers awards to exceptional postdoctoral researchers\, graduate trainees\, undergraduates students\, and faculty.  Awardees will be presented with a plaque and $1\,000 stipend and will be invited to present their work in brief Elevator Pitch format to the UCI academic community and the public at our annual CNLM Awards Ceremony. \n  \nApplications for the 2021 CNLM Awards are due in February. Stay tuned! \nFor more information\, please visit: https://cnlm.uci.edu/awards/ \n  URL:https://brain.uci.edu/event/2022-cnlm-awards-ceremony/ LOCATION:CNLM Herklotz Conference Center\, Irvine\, CA\, 92697\, United States CATEGORIES:All,Community,Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2022/02/cnlm-awards-slide-2022-01.png ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220525T160000 DTEND;TZID=America/Los_Angeles:20220525T170000 DTSTAMP:20260417T161157 CREATED:20220427T170241Z LAST-MODIFIED:20220427T170241Z UID:10000319-1653494400-1653498000@brain.uci.edu SUMMARY:Dr. Lim\, Stanford Neurosurgery Distinguished Lecture DESCRIPTION:The UCI Medical Scientist Training Program will be hosting the Chair of Neurosurgery at Stanford University\, Dr. Michael Lim\, for our final Distinguished Lecture of the year\, to present his research entitled “Overcoming Immune cell Exhaustion in Glioblastoma”. If you could distribute our attached fliers and info to your department’s faculty\, students\, and other members\, we would be very grateful. The lecture will available on May 25th in person at 4pm in Tamkin Hall  or on Zoom\, register here: https://uci.zoom.us/meeting/register/tJAtf-2vqj8pG9TUevwfkJf9fTKZ3coGH8ZQ. This information is also included in the attached HTML file. Thank you very much\, we are looking forward to learning from Dr. Lim and hope that members of your departments will be able to join the discussion. URL:https://brain.uci.edu/event/dr-lim-stanford-neurosurgery-distinguished-lecture/ LOCATION:Hybrid Event (In person at Tamkin Hall\, Telecast via Zoom)\, Irvine\, CA\, 92697\, United States CATEGORIES:All ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/052522-MSTP-Social-Ad_Michael.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220607T110000 DTEND;TZID=America/Los_Angeles:20220607T120000 DTSTAMP:20260417T161157 CREATED:20220517T152320Z LAST-MODIFIED:20220517T152320Z UID:10000324-1654599600-1654603200@brain.uci.edu SUMMARY:James L. McGaugh Distinguished Lecture: Kay Tye\, PhD DESCRIPTION:Neural Representations of Social Homeostasis \nJoin the UCI Department of Neurobiology and Behavior for a virtual seminar featuring\, Dr. Kay Tye of the Salk Institute. \nAbstract: \nHow does our brain rapidly determine if something is good or bad? How do we know our place within a social group? How do we know how to behave appropriately in dynamic environments with ever-changing conditions?\nThe Tye Lab is interested in understanding how neural circuits important for driving positive and negative motivational valence (seeking pleasure or avoiding punishment) are anatomically\, genetically and functionally arranged.  We study the neural mechanisms that underlie a wide range of behaviors ranging from learned to innate\, including social\, feeding\, reward-seeking and anxiety-related behaviors. We have also become interested in “social homeostasis” — how our brains establish a preferred set-point for social contact\, and how this maintains stability within a social group.  How are these circuits interconnected with one another\, and how are competing mechanisms orchestrated on a neural population level? We employ optogenetic\, electrophysiological\, electrochemical\, pharmacological and imaging approaches to probe these circuits during behavior. URL:https://brain.uci.edu/event/james-l-mcgaugh-distinguished-lecture-kay-tye-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-2.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220609T160000 DTEND;TZID=America/Los_Angeles:20220609T180000 DTSTAMP:20260417T161157 CREATED:20220524T152420Z LAST-MODIFIED:20220524T153522Z UID:10000326-1654790400-1654797600@brain.uci.edu SUMMARY:Society of Behavioral Medicine Information Event: Margaret Schneider\, PhD DESCRIPTION:An introduction to the Society of Behavioral Medicine: Professional development & networking opportunities for students & early-career scientists \nThe Society of Behavioral Medicine has the resources and tools you need to advance your career. SBM offers networking\, mentoring\, continuing education\, webinars\, presentation opportunities\, publication opportunities\, a Student Special Interest Group\, and much more. Join us for an information session organized by SBM leadership at UC Irvine featuring Dr. Margaret Schneider\, President of the Society of Behavioral Medicine. Come to learn and network with SBM members and fellow UCI scientists from all career stages. URL:https://brain.uci.edu/event/society-of-behavioral-medicine-information-event-margaret-schneider-phd/ LOCATION:Thorp Conference Center\, Gross Hall\, 4th Floor\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-5.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220614T100000 DTEND;TZID=America/Los_Angeles:20220614T110000 DTSTAMP:20260417T161157 CREATED:20220524T202757Z LAST-MODIFIED:20220525T214025Z UID:10000329-1655200800-1655204400@brain.uci.edu SUMMARY:Xiaoyu Shi\, PhD & Weian Zhao\, PhD DESCRIPTION:CNCM Seminar \nJoin the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Xiaoyu Shi and Dr. Weian Zhao of UC Irvine where they will be discussing: Molecular-resolution label-retention expansion microscopy (LR-ExM) and its application in brain mapping and Spatial omics using fluorescence spectral and lifetime imaging.  URL:https://brain.uci.edu/event/xiaoyu-shi-phd-weian-zhao-phd/ CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/Dr.-Zhao-and-Dr.-Shi.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220614T120000 DTEND;TZID=America/Los_Angeles:20220614T130000 DTSTAMP:20260417T161157 CREATED:20220602T201944Z LAST-MODIFIED:20220602T201944Z UID:10000331-1655208000-1655211600@brain.uci.edu SUMMARY:Albert La Spada\, PhD DESCRIPTION:Deconstructing Neurodegenerative Proteinopathies: From Pathology of Neuron Demise to Therapeutic Interventon \nJoin the Department of Neurobiology and Behavior in a hybrid seminar featuring Dr. Albert La Spada. \n \nAbstract:Both rare inherited neurodegenerative disorders and common sporadic neurodegenerative diseases are caused by misfolded proteins that accumulate in neurons and glia of affected patients.  The CAG – polyglutamine (PolyQ) repeat diseases are one category of inherited neurodegenerative disorders that are caused by the expansion of a CAG triplet repeat\, resulting in a protein with an abnormally extended polyglutamine (polyQ) tract.  The repeat expansions in these diseases occur in the coding region\, and lead to the production of aggregate-prone proteins.  Of the nine CAG-PolyQ diseases\, I have been studying the disease pathogenesis of three such disorders: X-linked spinal & bulbar muscular atrophy (SBMA/Kennedy’s disease)\, Huntington’s disease\, and spinocerebellar ataxia type 7.  To determine the cellular and molecular basis of these diseases\, I have relied upon mouse models and human stem cell models\, and through these efforts\, I have uncovered a central role for transcription dysregulation\, altered proteostasis\, and bioenergetic abnormalities in the pathogenesis of these disorders.  Unbiased transcriptome analysis and directed studies of cell-type contribution have yielded crucial insights into the nature of these diseases\, and have revealed targets and pathways likely amenable to therapeutic manipulation. \nHybrid Event\nThe seminar will be live-streamed via zoom and in person.\nPlease RSVP to let us know how you will attend and receive zoom link. \nIn-Person Meeting: Interdisciplinary Science and Engineering Building (ISEB) auditorium URL:https://brain.uci.edu/event/albert-la-spada-phd/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/06/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220614T130000 DTEND;TZID=America/Los_Angeles:20220614T140000 DTSTAMP:20260417T161157 CREATED:20220524T200759Z LAST-MODIFIED:20220524T201123Z UID:10000327-1655211600-1655215200@brain.uci.edu SUMMARY:C. Neill Epperson\, M.D. DESCRIPTION:Enduring Impact of Childhood Adversity: Multimodal Investigations Across the Lifespan \n\n\n\nJoin the Conte Center @ UCI in a virtual seminar featuring\, C. Neil Epperson\, M.D.\, Robert Freedman Endowed Chair and Professor of the Department of Psychiatry of the University of Colorado School of Medicine. URL:https://brain.uci.edu/event/c-neill-epperson-m-d/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-6.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220615T120000 DTEND;TZID=America/Los_Angeles:20220615T130000 DTSTAMP:20260417T161157 CREATED:20220524T203020Z LAST-MODIFIED:20220524T203148Z UID:10000330-1655294400-1655298000@brain.uci.edu SUMMARY:Virtual Lunch and Learn: Turning the Page as a Scientific Editor DESCRIPTION:  \n\n\n\n  \nGeorge Inglis\, PhD\nAssociate Editor at Communications Biology\n\n\n\nVirtual Lunch and Learn:\nTurning the Page as a Scientific Editor \nWednesday\, June 15\, 2022\n12 PM PT\nTelecast via Zoom \nFree to attend. Registration required. \n \nDr. Inglis is available for 1:1 meetings with any faculty or trainees interested in talking about their work. If interested\, please feel free to contact Dr. Inglis directly at george.inglis@us.nature.com or complete the journal’s meet-the-editor form via this link. \nSpeaker Bio:\nDr. George Inglis is an Associate Editor at Communications Biology\, an open-access journal in the Nature Portfolio that considers research articles\, reviews and commentary in all areas of the biological sciences. In this session\, Dr. Inglis will demystify the life science publishing landscape\, the role of an editor in the publication process\, and the career path to becoming an academic editor. He will also discuss the daily life of a research editor and ways to get involved in the editing or peer review process. Dr. Inglis received his BS in Biology from Pennsylvania State University in 2014\, and PhD in Genetics and Molecular Biology from Emory University in 2020. While at Emory\, he studied epigenomics\, mouse models of voltage-gated sodium channel dysfunction\, and in vitro models of neuronal development. George joined Communications Biology as an Associate Editor in September 2020 and is based in the New York office. \nEvent Contact: Robert Hunt\, PhD | robert.hunt@uci.edu \n  \nCo-Sponsored by URL:https://brain.uci.edu/event/virtual-lunch-and-learn-turning-the-page-as-a-scientific-editor/ LOCATION:Virtual Event CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/George-Inglis-PhD-06.15.22-1.jpg ORGANIZER;CN="UCI School of Medicine%2C Department of Anatomy &%3B Neurobiology":MAILTO:jdiazalo@uci.edu, lgng@hs.uci.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220621T100000 DTEND;TZID=America/Los_Angeles:20220621T110000 DTSTAMP:20260417T161157 CREATED:20220524T201753Z LAST-MODIFIED:20220627T220326Z UID:10000328-1655805600-1655809200@brain.uci.edu SUMMARY:Michael Wenzel\, PhD DESCRIPTION:EpiCenter Seminar Series\nJoin the UCI Epilepsy Research Center for a seminar featuring Michael Wenzel\, PhD\, Group Leader in the Department of Epileptology of the University Hospital Bonn. \n  URL:https://brain.uci.edu/event/michael-wenzel-phd/ LOCATION:Virtual Event CATEGORIES:Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/05/image-7.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220712T010000 DTEND;TZID=America/Los_Angeles:20220712T140000 DTSTAMP:20260417T161157 CREATED:20220629T162614Z LAST-MODIFIED:20220711T195039Z UID:10000332-1657587600-1657634400@brain.uci.edu SUMMARY:Canceled: “Why and how does early adversity influence development? Toward an integrated model of dimensions of environmental experience.” DESCRIPTION:Bruce J. Ellis\, Ph.D.\nProfessor of Psychology and Anthropology\nThe University of Utah\n\n\n\nCANCELED: “Why and how does early adversity influence development? Toward an integrated model of dimensions of environmental experience.”\nHost: Elysia Davis\, PhD\nTuesday\, July 12th\, 2022\n1 – 2 p.m. PT Telecast via Zoom \nEvent Contact: James Weinstock | jweinsto@hs.uci.edu URL:https://brain.uci.edu/event/why-and-how-does-early-adversity-influence-development-toward-an-integrated-model-of-dimensions-of-environmental-experience/ LOCATION:Telecast via Zoom CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/06/bruce_ellis.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220815T080000 DTEND;TZID=America/Los_Angeles:20220816T170000 DTSTAMP:20260417T161157 CREATED:20220428T230711Z LAST-MODIFIED:20220428T230711Z UID:10000320-1660550400-1660669200@brain.uci.edu SUMMARY:Linking Brain Function to Cell Types and Circuits DESCRIPTION:This two-day in-person conference will take place at the Beckman Center in Irvine\, CA. An in-person conference is not only an avenue for scientists to share their research with their peers\, but also an avenue for engaged discussions and networking. Such an event offers intellectual stimulation and rewarding experiences that a virtual\, online meeting can not offer. \nThere is a $175 fee for UCI affiliates and $189 fee for general admission required to cover the conference\, food and beverage expenses. Please register early due to our capacity of hosting ~120 attendees. Conference attendees are encouraged to submit a 1-page abstract (<500 words) by July 5. The attendee abstracts submitted will be selected for short talks or poster presentations. Use the link above to submit. \nWe will work with the Beckman staff to implement proper guidelines to ensure that this conference will be a safe and healthy event. This will involve social distancing\, temperature screens\, and masks inside the building (masks policy continue to change\, we will keep all attendees informed). All speakers and participants must show proof of a Covid-19 vaccination upon entering the building. Submit proof of vaccination here. URL:https://brain.uci.edu/event/linking-brain-function-to-cell-types-and-circuits/ LOCATION:Beckman Center of the National Academies of Sciences & Engineering\, 100 Academy Wy\, Irvine\, CA\, 92617\, United States CATEGORIES:Community ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/04/unnamed.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220909T080000 DTEND;TZID=America/Los_Angeles:20220909T153000 DTSTAMP:20260417T161157 CREATED:20220829T183218Z LAST-MODIFIED:20220829T184251Z UID:10000335-1662710400-1662737400@brain.uci.edu SUMMARY:33rd Annual Southern California Alzheimer’s Disease Research Conference DESCRIPTION:Dementia across the lifespan…\nJoin UCI MIND\, Alzheimer’s Orange County\, and Alzheimer’s Association for the 33rd Annual Southern California Alzheimer’s Disease Research Conference. This hybrid conference will cover a wide range of topics across the lifespan\, such as Down syndrome\, frontotemporal dementia\, early-onset Alzheimer’s\, the oldest-old\, and even more.To view the agenda\, see our exhibitors\, read about our esteemed speakers\, and more\, visit conference.mind.uci.edu. \nThis is a hybrid event\, taking place in person at the Irvine Marriott Hotel and virtually via Zoom.  \n  \n  URL:https://brain.uci.edu/event/33rd-annual-southern-california-alzheimers-disease-research-conference/ LOCATION:Irvine Marriott Hotel\, 18000 Von Karman Ave\, Irvine\, CA\, 92612 CATEGORIES:All,Community,Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/2022-Alzheimers-Conference.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220913T160000 DTEND;TZID=America/Los_Angeles:20220913T170000 DTSTAMP:20260417T161157 CREATED:20220829T181639Z LAST-MODIFIED:20220829T181834Z UID:10000334-1663084800-1663088400@brain.uci.edu SUMMARY:Susan B. Perlman\, PhD DESCRIPTION:Neuroscientific Evaluation of Risk in Early Childhood Psychopathology: Integrating Proximal and Distal Factors. \n\n\n\nJoin the Conte Center at UCI for a seminar featuring Dr. Susan B. Perlman\, Associate Professor of Psychiatry at the Washington University of St. Louis. \nTo learn more\, please visit: https://contecenter.uci.edu/seminar-series/ URL:https://brain.uci.edu/event/susan-b-perlman-phd/ LOCATION:Virtual/Hybrid Event (In person at Gross Hall 4th Floor Conference Room)\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/image-1-e1661797027822.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220920T100000 DTEND;TZID=America/Los_Angeles:20220920T110000 DTSTAMP:20260417T161157 CREATED:20220829T183851Z LAST-MODIFIED:20220829T184131Z UID:10000336-1663668000-1663671600@brain.uci.edu SUMMARY:Maurizio Taglialatela\, MD\, PhD DESCRIPTION:EpiCenter Seminar Series  \nJoin the UCI Epilepsy Research Center featuring Maurizio Taglialatela\, MD\, PhD\, Professor of Pharmacology\, University of Naples Federico II\, in a virtual seminar. URL:https://brain.uci.edu/event/maurizio-taglialatela-md-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/Maurizio-Taglialatela.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220920T100000 DTEND;TZID=America/Los_Angeles:20220920T110000 DTSTAMP:20260417T161157 CREATED:20220829T180611Z LAST-MODIFIED:20220829T180611Z UID:10000333-1663668000-1663671600@brain.uci.edu SUMMARY:Li Zhang\, Ph.D DESCRIPTION:CNCM Seminar  \nJoin the UCI Center for Neural Circuit Mapping in a seminar featuring Dr. Li Zhang\, Professor of Physiology & Neuroscience and Director of the Center for Neural Circuits and Sensory Processing Disorders of the Keck School of Medicine of USC. URL:https://brain.uci.edu/event/li-zhang-ph-d/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/08/image.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20220928T100000 DTEND;TZID=America/Los_Angeles:20220928T110000 DTSTAMP:20260417T161157 CREATED:20220913T183033Z LAST-MODIFIED:20220913T183033Z UID:10000338-1664359200-1664362800@brain.uci.edu SUMMARY:CNCM Seminar: Peyman Golshani\, MD\, PhD DESCRIPTION:New open-source tools for imaging neuronal activity in freely behaving animals \nJoin the UCI Center for Neural Circuit Mapping in a hybrid conference featuring Dr. Peyman Golshani\, Professor of Neurology at the David Geffen School of Medicine\, UCLA. \nAbstract: \nDr. Golshani obtained his MD/PhD from UC Irvine and UC Davis where he trained under the mentorship of Dr. Edward G. Jones on the development of corticothalamic synapse. He then completed his Neurology residency at UCLA and obtained postdoctoral training with Dr. Felix Schweizer and Dr. Guoping Fan where he studied the role of DNA methylation in development of cortical circuits. He then became faculty and in collaboration with Dr. Portera-Cailliau and Dr. Stelios Smirnakis studied the developmental desynchronization of internally generated activity in the cerebral cortex. His independent laboratory now investigates how cortical microcircuits in the awake behaving animal encode sensory input and how disorders such as autism and developmental epilepsies disrupt functional cortical connectivity. \nHybrid Seminar \nIn-Person: Interdisciplinary Science & Engineering Building ISEB 2020 \nVirtual: via Zoom URL:https://brain.uci.edu/event/cncm-seminar-peyman-golshani-md-phd/ LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/Peyman-Golshani-400x400-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221004T100000 DTEND;TZID=America/Los_Angeles:20221004T110000 DTSTAMP:20260417T161157 CREATED:20220929T153733Z LAST-MODIFIED:20220929T154020Z UID:10000350-1664877600-1664881200@brain.uci.edu SUMMARY:Rongxin Fang\, PhD DESCRIPTION:Analysis of Cortical Evolution with Specially Resolved Transcriptome Imaging \nJoin the UCI Center for Neural Circuit Mapping in a virtual seminar featuring Dr. Rongxin Fang. Dr. Fang is currently a Howard Hughes Medical Institute fellow of the Dameon Runyon Cancer Research Foundation at Harvard University. He received his Ph.D in Bioinformatics at the University of California\, San Diego. URL:https://brain.uci.edu/event/rongxin-fang-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-5.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221004T110000 DTEND;TZID=America/Los_Angeles:20221004T120000 DTSTAMP:20260417T161157 CREATED:20220913T175619Z LAST-MODIFIED:20220913T175640Z UID:10000337-1664881200-1664884800@brain.uci.edu SUMMARY:Neurobiology and Behavior Seminar with Dr. Alan Urban DESCRIPTION:How can functional ultrasound imaging (fUSI) impact your research\, and what’s next? \nJoin the UCI Department of Neurobiology and Behavior in a hybrid seminar featuring Dr. Alan Urban\, Assistant Professor of the Department of Neurosciences of KU Leuven Research. \nAbstract: \nFunctional ultrasound imaging (fUSI) is based on Doppler ultrasound to track changes in cerebral blood volume as an indirect readout of evoked neuronal activity. It is similar to fMRI but with better spatiotemporal resolution and fewer technical constraints. Indeed\, fUSI can be performed in head-fixed or freely behaving rodents and allows volumetric images of the entire mouse brain. Proof of concept studies has been conducted in many species\, including primates and humans. fUSI has reached maturity\, and open access hardware and software solutions developed at NERF contribute to a faster and broader adoption by the neuroscience community. This seminar aims to introduce the physical basis of fUSI and present state-of-the-art in the field while providing detailed examples of the most impactful fUSI research. I will also discuss the latest capabilities of fUSI and suggest routes for improving the fUSI technology in the next few years. \nHybrid Event\nThe seminar will be live-streamed via zoom and in person.\nPlease RSVP to let us know how you will attend and receive zoom link. \nIn-Person Meeting: Dale Melbourne Herklotz Conference Room\, the Center for the Neurobiology of Learning and Memory 300 Qureshey Research Lab URL:https://brain.uci.edu/event/neurobiology-and-behavior-seminar-with-dr-alan-urban/ LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/Alan-Urban.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221007T100000 DTEND;TZID=America/Los_Angeles:20221007T110000 DTSTAMP:20260417T161157 CREATED:20220929T160851Z LAST-MODIFIED:20220929T161201Z UID:10000353-1665136800-1665140400@brain.uci.edu SUMMARY:Serena M. Dudek\, PhD DESCRIPTION:Join the Department of Anatomy and Neurobiology in a virtual seminar featuring Dr. Serena M. Dudek \, Deputy Chief and Neurobiology Laboratory and Principal Investigator of the National Institute of Environmental Health Sciences. URL:https://brain.uci.edu/event/serena-m-dudek-phd/ LOCATION:Virtual Event CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-8-e1664467912680.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221007T120000 DTEND;TZID=America/Los_Angeles:20221007T130000 DTSTAMP:20260417T161157 CREATED:20221004T205910Z LAST-MODIFIED:20221004T210115Z UID:10000355-1665144000-1665147600@brain.uci.edu SUMMARY:BME Seminar Series: How does neuronal activity protect the cortex from stroke? DESCRIPTION:Abstract: Stroke is the fifth leading cause for death in the U.S. and No. 1 cause for long term disability. Traditionally\, stroke has been studied in animal models using cellular and molecular techniques\, but little attention has been paid to neuronal activity. In this talk\, I will describe surprising findings in a rat model of ischemic stroke relating sensory stimulation-evoked neuronal activity and stroke. Depending on delivery timing\, sensory stimulation-evoked neuronal activity can protect the cortex from impending damage or exacerbate the damage. I will further elucidate the neuronal and vascular mechanisms underlying the protection and exacerbation processes and describe our accumulating evidence that neuronal activity and cortical structure-function relationship are pivotal players in understanding ischemic stroke outcome. \nBiography: Ron D. Frostig is a professor of neurobiology and behavior and biomedical engineering at UCI. He received his bachelor’s degree in biology and his master’s degree in neurobiology from the Hebrew University\, Israel. He received his doctorate in neuroscience at UCLA\, and was a postdoctoral research scholar in neurobiology at the Rockefeller University. His lab’s major research interests include basic and pre-clinical studies of neocortical structure and function with an emphasis on plasticity. URL:https://brain.uci.edu/event/bme-seminar-series-how-does-neuronal-activity-protect-the-cortex-from-stroke/ LOCATION:McDonnell Douglas Engineering Auditorium\, 314 Los Trancos Drive\, Irvine\, CA\, 92697\, United States CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/FrostigLab-Logo-v7.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221011T100000 DTEND;TZID=America/Los_Angeles:20221011T110000 DTSTAMP:20260417T161157 CREATED:20220929T154800Z LAST-MODIFIED:20220929T154800Z UID:10000351-1665482400-1665486000@brain.uci.edu SUMMARY:Sean Foxley\, PhD DESCRIPTION:Join the UCI Center for Neural Circuit Mapping in a hybrid seminar featuring Dr. Sean Foxley of the University of Chicago. URL:https://brain.uci.edu/event/sean-foxley-phd/ CATEGORIES:Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/09/image-6.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/Los_Angeles:20221019T120000 DTEND;TZID=America/Los_Angeles:20221019T160000 DTSTAMP:20260417T161157 CREATED:20221005T155834Z LAST-MODIFIED:20221005T155935Z UID:10000356-1666180800-1666195200@brain.uci.edu SUMMARY:UC Irvine Neuropolitics Symposium DESCRIPTION:Cognitive Decline and Political Leadership \nJoin the UCI Center for Neuropolitics in a virtual symposium to discuss cognitive decline among politicians. \nCognitive deterioration of politicians (including diminished memory\, impaired decision-\nmaking\, mood alterations\, and dementia) is a critical emerging issue. This Symposium\nwill address the current state and future directions of assessment of cognitive function\nand decline among politicians. As professions such as law and medicine are addressing\ncognitive effects of age\, their insights may inform development of the proper strategy\nwithin politics. \n  \nClick here to view the symposium agenda URL:https://brain.uci.edu/event/uc-irvine-neuropolitics-symposium/ LOCATION:Virtual Event CATEGORIES:Community,Faculty,Scientific,Staff,Students ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2022/10/image.jpeg END:VEVENT END:VCALENDAR