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X-WR-CALDESC:Events for Brain
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DTSTART;TZID=America/Los_Angeles:20240312T100000
DTEND;TZID=America/Los_Angeles:20240312T110000
DTSTAMP:20260404T192006
CREATED:20240125T233026Z
LAST-MODIFIED:20240125T234220Z
UID:10000467-1710237600-1710241200@brain.uci.edu
SUMMARY:Keri Martinowich\, PhD
DESCRIPTION:Associate Professor\, Department of Psychiatry and Behavioral Sciences Keri Martinowich\, PhD from Johns Hopkins University Presents: \n“Cell type and spatially-resolved multiomic approaches for understanding human brain disorders” \nHybrid: ISEB 1200 & Zoom
URL:https://brain.uci.edu/event/keri-martinowich-phd/
LOCATION:Interdisciplinary Science and Engineering Building (ISEB) and Virtually Via Zoom\, 419 Physical Sciences Quad\, Irvine\, 92697\, United States
ATTACH;FMTTYPE=image/png:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Untitled-design-11.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240312T110000
DTEND;TZID=America/Los_Angeles:20240312T120000
DTSTAMP:20260404T192006
CREATED:20231009T215405Z
LAST-MODIFIED:20240130T163208Z
UID:10000433-1710241200-1710244800@brain.uci.edu
SUMMARY:Christian Bravo Rivera\, Ph.D.
DESCRIPTION:CNLM Colloquium Series \nJoin the Center for the Neurobiology of Learning and Memory (CNLM) for a hybrid event featuring Dr. Christian Bravo Rivera\, assistant professor of psychiatry\, anatomy\, and neurobiology. This event will be held in-person in the Herklotz Conference Center and virtually via Zoom. \nNeural circuits mediating reward approach and punishment avoidance conflict  \nReward is often present in risky environments\, requiring individuals to weigh the benefits of rewards against the associated risks. There are individuals that are unable to choose an appropriate response during risky reward opportunities and thus exhibit extreme avoidance or risky behaviors that can severely impair quality of life or endanger people. It is therefore necessary to characterize how neurons mediate reward approach and threat avoidance conflict. Here\, we adapted the platform-mediated avoidance conflict task (Bravo-Rivera et al 2014; Bravo-Rivera et al 2021)\, such that water-deprived mice could nose-poke for a light-signaled water reward and avoid a tone-signaled foot-shock by stepping onto a safety platform away from the reward port. Optogenetic activation of GABAergic neurons in the ventral pallidum invigorated reward approach at the expense of receiving shocks. Photometry recordings of glutamatergic neurons in the ventral pallidum and in the lateral habenula during conflict revealed that these structures promote avoidance and become inhibited during conflicted reward approach. These results suggest that a pallidal-habenula circuit mediates motivational conflict. We also compared behavioral conflict in male and female mice. Interestingly\, females stepped on the platform earlier than males after tone onset and took longer to leave the platform after tone offset. Males received more shocks than females and received more water reward than females by the end conflict training. Moreover\, females exhibited more tone-induced freezing and exhibited more frequent darting than males. These results suggest that females exhibit more avoidance behavior and less reward approach than males in the face of approach/avoidance conflict.
URL:https://brain.uci.edu/event/christian-bravo-rivera-ph-d/
LOCATION:CNLM Herklotz Conference Center and Virtually via Zoom
CATEGORIES:Faculty,Scientific,Staff,Students,Students, Faculty, Staff Only
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ORGANIZER;CN="UCI Center for the Neurobiology of Learning and Memory":MAILTO:memory@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240313T120000
DTEND;TZID=America/Los_Angeles:20240313T130000
DTSTAMP:20260404T192006
CREATED:20240307T161631Z
LAST-MODIFIED:20240307T163003Z
UID:10000511-1710331200-1710334800@brain.uci.edu
SUMMARY:Robert Zatorre\, PhD
DESCRIPTION:The Department of  Cognitive Sciences’ Colloquia Series presents guest speaker Dr. Robert Zatorre\, a professor in the Department of Psychology at Montreal Neurological Institute\, McGill University. \nFrom Perception to Pleasure. The Neuroscience of Music and Why We Love It \nMusic has existed in human societies since prehistory\, likely because it allows expression and regulation of emotion\, and evokes pleasure. In this lecture I will present findings from cognitive neuroscience that bear on the question of how we get from perception of sound patterns to pleasurable responses. I will first discuss evidence that corticocortical loops from and to the auditory cortex are responsible not only for perceptual processes but also for working memory\, sensory-motor\, and predictive functions that are essential to produce and perceive music. Then\, I will discuss neuroimaging and brain modulation studies from our lab focusing on the dopaminergic reward system\, its involvement in musical pleasure\, and what happens when that system is disrupted. I propose that pleasure in music arises from interactions between cortical loops that enable expectancies to emerge from perceived sound patterns\, and subcortical systems responsible for reward and valuation. This model integrates knowledge derived from basic neuroscience of reward mechanisms with independently derived concepts\, such as tension and anticipation\, from music theory. It may also serve as a way of thinking more broadly about aesthetic rewards.
URL:https://brain.uci.edu/event/robert-zatorre-phd/
LOCATION:Virtual via Zoom\, CA
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240314T110000
DTEND;TZID=America/Los_Angeles:20240314T120000
DTSTAMP:20260404T192006
CREATED:20240208T235302Z
LAST-MODIFIED:20240209T161652Z
UID:10000494-1710414000-1710417600@brain.uci.edu
SUMMARY:Krishna Jayant\, PhD
DESCRIPTION:The department of Anatomy & Neurobiology will host guest speaker Dr. Krishna Jayant\, an assistant professor from Purdue University. \nA translaminar space-time code supports touch-evoked traveling waves \nTraveling waves in mammalian cortex mediate vital aspects of animal cognition\, such as stimuli perception and working memory. Theoretical results suggest that these waves preserve timing and are critical for plasticity across long-range neural circuits. Therefore\, revealing the circuit mechanisms underlying sensory-evoked traveling waves is critical to understanding the neural basis of sensory perception. In this talk\, I will describe our recent efforts in using 2D nanotextured transparent ECoG style electrodes to map circuits orchestrating wave dynamics. Specifically\, by simultaneously mapping local-field-potentials and cellular ensemble dynamics (via 2P calcium imaging)\, we will describe the circuit features tied to traveling waves under active and passive whisker touch. We will show that in awake mice\, both passive and active whisker touch elicited traveling waves within and across barrels\, with both an early and late component lasting hundreds of milliseconds.  Strikingly\, wave dynamics reflected the value of the tactile stimulus\, and was found to be shaped by reinforcement learning. We will also describe how the late wave component is i) strongly modulated by motor feedback\, ii) complements a sparse ensemble pattern across layer 2/3 which we resolved via a balanced-state network model with distributed top-down feedback\, and iii) aligns with regenerative Layer 5 apical dendritic Ca2+ spikes. Our results establish a model in which translaminar spacetime patterns\, organized by motor cortical feedback\, sculpt touch-evoked traveling waves.
URL:https://brain.uci.edu/event/krishna-jayant-phd/
LOCATION:Plumwood House\, 1003 Health Sciences Rd\, Irvine\, CA 92617\, Irvine\, CA\, 92697\, United States
CATEGORIES:Community,Faculty,Scientific,Staff,Students
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240315T120000
DTEND;TZID=America/Los_Angeles:20240315T131500
DTSTAMP:20260404T192006
CREATED:20240131T220057Z
LAST-MODIFIED:20240131T220057Z
UID:10000472-1710504000-1710508500@brain.uci.edu
SUMMARY:Presidential Leadership and Disability
DESCRIPTION:The age of presidential candidates has become a salient concern\, but age is not the only physical factor that should concern citizens. Presidents can also suffer various forms of illness\, both physical and psychological. This talk highlights the nature of these concerns and how we might work to mitigate their impact on political outcomes. \nFree registration is open now: https://uci.zoom.us/webinar/register/WN_m5HtweYgSh6t9sGnAa_hOQ#/registration \nFor more details\, please visit: https://sites.uci.edu/centerforneuropolitics/
URL:https://brain.uci.edu/event/presidential-leadership-and-disability/
LOCATION:Zoom Webinar
CATEGORIES:All,Community,Faculty,Scientific,Staff,Students
ATTACH;FMTTYPE=image/jpeg:https://brain.uci.edu/wp-content/uploads/sites/49/2024/01/Neuropolitics-Social-Ad_FridayMarch5th2024_-scaled.jpg
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